An unexpected journey: conceptual evolution of mechanoregulated potassium transport in the distal nephron

WNK1 Activates Large-Conductance Ca2+-Activated K+ Channels through Modulation of ERK1/2 Signaling

(2014) Y. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Emerging Role of the Calcium-Activated, Small Conductance, SK3 K+ Channel in Distal Tubule Function: Regulation by TRPV4

(2014) Jonathan Berrout et al.   PLoS One

S-acylation dependent post-translational cross-talk regulates large conductance calcium- and voltage- activated potassium (BK) channels

(2014) Michael J. Shipston   Frontiers in Physiology

Regulation of BK channels by auxiliary γ subunits

(2014) Jiyuan Zhang et al.   Frontiers in Physiology

Regulation of large-conductance Ca2+-activated K+ channels by WNK4 kinase

(2013) Zhijian Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

WNK4 inhibits Ca2+-activated big-conductance potassium channels (BK) via mitogen-activated protein kinase-dependent pathway

(2013) Peng Yue et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mineralocorticoid Receptor Phosphorylation Regulates Ligand Binding and Renal Response to Volume Depletion and Hyperkalemia

(2013) Shigeru Shibata et al.   Cell Metabolism

Renal β-intercalated cells maintain body fluid and electrolyte balance

(2013) Victor Gueutin et al.   JOURNAL OF CLINICAL INVESTIGATION

Rapid dephosphorylation of the renal sodium chloride cotransporter in response to oral potassium intake in mice

(2013) Mads V. Sorensen et al.   KIDNEY INTERNATIONAL

Primary cilia are specialized calcium signalling organelles

(2013) Markus Delling et al.   NATURE

Genetically encoded calcium indicator illuminates calcium dynamics in primary cilia

(2013) Steven Su et al.   NATURE METHODS

Renal intercalated cells are rather energized by a proton than a sodium pump

(2013) R. Chambrey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Function of Transient Receptor Potential Cation Channel Subfamily V Member 4 (TRPV4) as a Mechanical Transducer in Flow-sensitive Segments of Renal Collecting Duct System

(2012) Jonathan Berrout et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Primary cilium-dependent sensing of urinary flow and paracrine purinergic signaling

(2012) Helle A. Praetorius et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

An Integrative Review of Mechanotransduction in Endothelial, Epithelial (Renal) and Dendritic Cells (Osteocytes)

(2011) Sheldon Weinbaum et al.   Cellular and Molecular Bioengineering

The WNK Kinase Network Regulating Sodium, Potassium, and Blood Pressure

(2011) E. J. Hoorn et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Purinergic Activation of Ca2+-Permeable TRPV4 Channels Is Essential for Mechano-Sensitivity in the Aldosterone-Sensitive Distal Nephron

(2011) Mykola Mamenko et al.   PLoS One

Conserved BK Channel-Protein Interactions Reveal Signals Relevant to Cell Death and Survival

(2011) Bernd Sokolowski et al.   PLoS One

Serum and Glucocorticoid-induced Kinase (SGK) 1 and the Epithelial Sodium Channel Are Regulated by Multiple with No Lysine (WNK) Family Members

(2010) Charles J. Heise et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Na+-dependent chloride-bicarbonate exchanger SLC4A8 mediates an electroneutral Na+ reabsorption process in the renal cortical collecting ducts of mice

(2010) Françoise Leviel et al.   JOURNAL OF CLINICAL INVESTIGATION

Intercalated Cell BK- / 4 Channels Modulate Sodium and Potassium Handling During Potassium Adaptation

(2010) J. D. Holtzclaw et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Multigene kinase network, kidney transport, and salt in essential hypertension

(2010) Paul A. Welling et al.   KIDNEY INTERNATIONAL

LRRC26 auxiliary protein allows BK channel activation at resting voltage without calcium

(2010) Jiusheng Yan et al.   NATURE

Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension

(2010) J. Hadchouel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WNK4 Diverts the Thiazide-sensitive NaCl Cotransporter to the Lysosome and Stimulates AP-3 Interaction

(2009) Arohan R. Subramanya et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Connexin 30 Deficiency Impairs Renal Tubular ATP Release and Pressure Natriuresis

(2009) A. Sipos et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Hypertension of Kcnmb1−/−is linked to deficient K secretion and aldosteronism

(2009) P. Richard Grimm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

K restriction inhibits protein phosphatase 2B (PP2B) and suppression of PP2B decreases ROMK channel activity in the CCD

(2008) Yan Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

TRPP2 and TRPV4 form a polymodal sensory channel complex

(2008) Michael Köttgen et al.   JOURNAL OF CELL BIOLOGY

Epoxyeicosatrienoic Acid Activates BK Channels in the Cortical Collecting Duct

(2008) P. Sun et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Basolateral Na+/H+ exchange maintains potassium secretion during diminished sodium transport in the rabbit cortical collecting duct

(2008) Shigeaki Muto et al.   KIDNEY INTERNATIONAL

Profiling the Phospho-status of the BKCaChannel α Subunit in Rat Brain Reveals Unexpected Patterns and Complexity

(2008) Jiusheng Yan et al.   MOLECULAR & CELLULAR PROTEOMICS