Encapsulation of the Dinuclear Trithiolato-Bridged Arene Ruthenium Complex Diruthenium-1 in an Apoferritin Nanocage: Structure and Cytotoxicity

Caged noble metals: Encapsulation of a cytotoxic platinum(II)-gold(I) compound within the ferritin nanocage

(2018) Giarita Ferraro et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Characterizing metal-binding sites in proteins with X-ray crystallography

(2018) Katarzyna B Handing et al.   Nature Protocols

Cisplatin Binding Sites in Human H-Chain Ferritin

(2017) Giarita Ferraro et al.   INORGANIC CHEMISTRY

Principles and methods used to grow and optimize crystals of protein–metallodrug adducts, to determine metal binding sites and to assign metal ligands

(2017) Irene Russo Krauss et al.   Metallomics

X-ray Structure of the Carboplatin-Loaded Apo-Ferritin Nanocage

(2017) Nicola Pontillo et al.   ACS Medicinal Chemistry Letters

Observation of gold sub-nanocluster nucleation within a crystalline protein cage

(2017) Basudev Maity et al.   Nature Communications

Protein Nanocages for Delivery and Release of Luminescent Ruthenium(II) Polypyridyl Complexes

(2016) Xiao Li et al.   ACS Applied Materials & Interfaces

In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [(η6-p-MeC6H4Pri)2Ru2(μ-S-p-C6H4OH)3]Cl

(2016) Darina Muthná et al.   ANTI-CANCER DRUGS

Design of a confined environment using protein cages and crystals for the development of biohybrid materials

(2016) Satoshi Abe et al.   CHEMICAL COMMUNICATIONS

Immobilization of two organometallic complexes into a single cage to construct protein-based microcompartments

(2016) Basudev Maity et al.   CHEMICAL COMMUNICATIONS

Gold-based drug encapsulation within a ferritin nanocage: X-ray structure and biological evaluation as a potential anticancer agent of the Auoxo3-loaded protein

(2016) Giarita Ferraro et al.   CHEMICAL COMMUNICATIONS

Cisplatin encapsulation within a ferritin nanocage: a high-resolution crystallographic study

(2016) Nicola Pontillo et al.   CHEMICAL COMMUNICATIONS

Insights into the in vitro Anticancer Effects of Diruthenium-1

(2016) Aneta Koceva-Chyła et al.   ChemMedChem

Thiolato-bridged dinuclear arene ruthenium complexes and their potential as anticancer drugs

(2016) Julien Furrer et al.   COORDINATION CHEMISTRY REVIEWS

Interactions between proteins and Ru compounds of medicinal interest: A structural perspective

(2016) Antonello Merlino   COORDINATION CHEMISTRY REVIEWS

Thirty Years of the Drug Candidate NAMI-A and the Myths in the Field of Ruthenium Anticancer Compounds: A Personal Perspective

(2016) Enzo Alessio   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Apoferritin nanocage as drug reservoir: is it a reliable drug delivery system?

(2016) Giovanni Tosi et al.   Expert Opinion on Drug Delivery

Dinuclear arene ruthenium thiolato complexes with fluorous side-chains

(2016) David Stíbal et al.   INORGANICA CHIMICA ACTA

Effect of temperature on the interaction of cisplatin with the model protein hen egg white lysozyme

(2016) Giarita Ferraro et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

X-ray Structure Analysis of Indazolium trans-[Tetrachlorobis(1H-indazole)ruthenate(III)] (KP1019) Bound to Human Serum Albumin Reveals Two Ruthenium Binding Sites and Provides Insights into the Drug Binding Mechanism

(2016) Aleksandar Bijelic et al.   JOURNAL OF MEDICINAL CHEMISTRY

Carotenoids in fresh and processed tomato (Solanum lycopersicum) fruits protect cells from oxidative stress injury

(2016) Rita Del Giudice et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Hydrolytic behaviour of mono- and dithiolato-bridged dinuclear arene ruthenium complexes and their interactions with biological ligands

(2016) David Stíbal et al.   RSC Advances

Use of the confined spaces of apo-ferritin and virus capsids as nanoreactors for catalytic reactions

(2015) Basudev Maity et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

[( p- MeC 6 H 4 Pr i ) 2 Ru 2 (SC 6 H 4 - p -Bu t ) 3 ]Cl ( diruthenium-1 ), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study

(2015) Pavel Tomšík et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Interactions of arene ruthenium metallaprisms with human proteins

(2015) Lydia E. H. Paul et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

(2015) András Micsonai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

H-Chain Ferritin: A Natural Nuclei Targeting and Bioactive Delivery Nanovector

(2015) Lianbing Zhang et al.   Advanced Healthcare Materials

Mixed-ligand ruthenium polypyridyl complexes as apoptosis inducers in cancer cells, the cellular translocation and the important role of ROS-mediated signaling

(2014) Zhennan Zhao et al.   DALTON TRANSACTIONS

Intracellular CO Release from Composite of Ferritin and Ruthenium Carbonyl Complexes

(2014) Kenta Fujita et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

RGD-Modified Apoferritin Nanoparticles for Efficient Drug Delivery to Tumors

(2013) Zipeng Zhen et al.   ACS Nano

A ruthenium(II) β-carboline complex induced p53-mediated apoptosis in cancer cells

(2013) Yu Chen et al.   BIOCHIMIE

Apoferritin Modified Magnetic Particles as Doxorubicin Carriers for Anticancer Drug Delivery

(2013) Iva Blazkova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

MTT assay for cell viability: Intracellular localization of the formazan product is in lipid droplets

(2012) Juan C. Stockert et al.   ACTA HISTOCHEMICA

Highly cytotoxic trithiophenolatodiruthenium complexes of the type [(η6-p-MeC6H4Pr i )2Ru2(SC6H4-p-X)3]+: synthesis, molecular structure, electrochemistry, cytotoxicity, and glutathione oxidation potential

(2012) Federico Giannini et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Construction of nanometer cisplatin core-ferritin (NCC-F) and proteomic analysis of gastric cancer cell apoptosis induced with cisplatin released from the NCC-F

(2012) Xue-Tao Ji et al.   Journal of Proteomics

CaSeO4·0.625H2O – water channel occupation in a bassanite related structure

(2011) Susanne Fritz et al.   ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE

Thiolato-Bridged Arene-Ruthenium Complexes: Synthesis, Molecular Structure, Reactivity, and Anticancer Activity of the Dinuclear Complexes [(arene)2Ru2(SR)2Cl2]

(2011) Anne-Flore Ibao et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Efficient Oxidation of Cysteine and Glutathione Catalyzed by a Dinuclear Areneruthenium Trithiolato Anticancer Complex

(2011) Federico Giannini et al.   INORGANIC CHEMISTRY

Organometallic Ruthenium(II) Arene Compounds with Antiangiogenic Activity

(2011) Patrycja Nowak-Sliwinska et al.   JOURNAL OF MEDICINAL CHEMISTRY

Thiophenolato-bridged dinuclear arene ruthenium complexes: a new family of highly cytotoxic anticancer agents

(2010) Michaël Gras et al.   DALTON TRANSACTIONS

Incorporation of organometallic Ru complexes into apo-ferritin cage

(2010) Yusuke Takezawa et al.   DALTON TRANSACTIONS

Structure and flexibility in cold-adapted iron superoxide dismutases: The case of the enzyme isolated from Pseudoalteromonas haloplanktis

(2010) Antonello Merlino et al.   JOURNAL OF STRUCTURAL BIOLOGY

Areneruthenium complexes as anticancer agents

(2009) Georg Süss-Fink   DALTON TRANSACTIONS

Characterization and cellular uptake of platinum anticancer drugs encapsulated in apoferritin

(2009) Ruimin Xing et al.   JOURNAL OF INORGANIC BIOCHEMISTRY