Tetramethylpyrazine exerts a protective effect against injury from acute myocardial ischemia by regulating the PI3K/Akt/GSK-3β signaling pathway

Recombinant human brain natriuretic peptide regulates PI3K/AKT/mTOR pathway through lncRNA EGOT to attenuate hypoxia-induced injury in H9c2 cardiomyocytes

(2018) Chengxi Zhang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Shikonin protects H9C2 cardiomyocytes against hypoxia/reoxygenation injury through activation of PI3K/Akt signaling pathway

(2018) Shuang Wang et al.   BIOMEDICINE & PHARMACOTHERAPY

Acute transient myocardial ischemia: A common pathophysiological mechanism in takotsubo syndrome. Is it still a cardiomyopathy?

(2018) Michael Spartalis et al.   Journal of Cardiology

GSK3β inhibitor promotes myelination and mitigates muscle atrophy after peripheral nerve injury

(2018) Dian-ying Zhang et al.   Neural Regeneration Research

Isoproterenol-induced cardiac ischemia and fibrosis: Plant-based approaches for intervention

(2018) Prince Allawadhi et al.   PHYTOTHERAPY RESEARCH

FTI-277 inhibits smooth muscle cell calcification by up-regulating PI3K/Akt signaling and inhibiting apoptosis

(2018) Arvind Ponnusamy et al.   PLoS One

Metabolomic Profiling in Acute ST‐Segment–Elevation Myocardial Infarction Identifies Succinate as an Early Marker of Human Ischemia–Reperfusion Injury

(2018) Matthias Kohlhauer et al.   Journal of the American Heart Association

Cardioprotective role of FA against isoproterenol induced cardiac toxicity

(2018) Pankaj G. Jain et al.   MOLECULAR BIOLOGY REPORTS

Inflammageing: chronic inflammation in ageing, cardiovascular disease, and frailty

(2018) Luigi Ferrucci et al.   Nature Reviews Cardiology

Involvement of Endothelin 1 in Remote Preconditioning-Induced Cardioprotection through connexin 43 and Akt/GSK-3β Signaling Pathway

(2018) Min Zhang et al.   Scientific Reports

Protective effect of diethylcarbamazine inhibits NF-κB activation in isoproterenol-induced acute myocardial infarction rat model through the PARP pathway

(2017) Guowei Jia et al.   Molecular Medicine Reports

Tetramethylpyrazine reduces blood-brain barrier permeability associated with enhancement of peripheral cholinergic anti-inflammatory effects for treating traumatic brain injury

(2017) Aimin Wang et al.   Experimental and Therapeutic Medicine

PI3K/SGK1/GSK3β signaling pathway is involved in inhibition of autophagy in neonatal rat cardiomyocytes exposed to hypoxia/reoxygenation by hydrogen sulfide

(2016) Huan Jiang et al.   EXPERIMENTAL CELL RESEARCH

Remote Liver Ischemic Preconditioning Protects against Sudden Cardiac Death via an ERK/GSK-3β-Dependent Mechanism

(2016) Zhaoyang Hu et al.   PLoS One

Apigenin attenuates heart injury in lipopolysaccharide-induced endotoxemic model by suppressing sphingosine kinase 1/sphingosine 1-phosphate signaling pathway

(2015) Tianzhu Zhang et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Cardioprotective effects of timosaponin B II from Anemarrhenae asphodeloides Bge on isoproterenol-induced myocardial infarction in rats

(2015) Xue-Yang Deng et al.   CHEMICO-BIOLOGICAL INTERACTIONS

MicroRNA-181c targets Bcl-2 and regulates mitochondrial morphology in myocardial cells

(2015) Hongjiang Wang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

bFGF regulates autophagy and ubiquitinated protein accumulation induced by myocardial ischemia/reperfusion via the activation of the PI3K/Akt/mTOR pathway

(2015) Zhou-Guang Wang et al.   Scientific Reports

Regulation of signal transducer and activator of transcription 3 and apoptotic pathways by betaine attenuates isoproterenol-induced acute myocardial injury in rats

(2014) P Zheng et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Regulation of antioxidant system, lipids and fatty acid β-oxidation contributes to the cardioprotective effect of sodium tanshinone IIA sulphonate in isoproterenol-induced myocardial infarction in rats

(2013) Bo Wei et al.   ATHEROSCLEROSIS

Protective effects of naringenin on carbon tetrachloride-induced acute nephrotoxicity in mouse kidney

(2013) Anca Hermenean et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Editorial [Hot Topic: Cardiovascular Risk and Inflammation: Pathophysiological Mechanisms, Drug Design, and Targets Executive (Guest Editor: Armen Yuri Gasparyan)]

(2012) Armen Yuri Gasparyan   CURRENT PHARMACEUTICAL DESIGN

Synergistic protective effect of astragaloside IV–tetramethylpyrazine against cerebral ischemic-reperfusion injury induced by transient focal ischemia

(2011) Jiehong Yang et al.   JOURNAL OF ETHNOPHARMACOLOGY

SOD1 overexpression in paraventricular nucleus improves post-infarct myocardial remodeling and ventricular function

(2011) Juan Gao et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The cellular and molecular origin of reactive oxygen species generation during myocardial ischemia and reperfusion

(2011) Koen Raedschelders et al.   PHARMACOLOGY & THERAPEUTICS