Do porcine Sertoli cells represent an opportunity for Duchenne muscular dystrophy?

Exon skipping for Duchenne muscular dystrophy: a systematic review and meta-analysis

(2018) Yuko Shimizu-Motohashi et al.   Orphanet Journal of Rare Diseases

Why was PERV not transmitted during preclinical and clinical xenotransplantation trials and after inoculation of animals?

(2018) Joachim Denner   Retrovirology

Sertoli cells for cell transplantation: pre-clinical studies and future perspectives

(2018) G. Luca et al.   Andrology

The potential of utrophin modulators for the treatment of Duchenne muscular dystrophy

(2018) Simon Guiraud et al.   Expert Opinion on Orphan Drugs

Induced Pluripotent Stem Cells for Duchenne Muscular Dystrophy Modeling and Therapy

(2018) Lubos Danisovic et al.   Cells

Production of Macrophage Inhibitory Factor (MIF) by Primary Sertoli Cells; Its Possible Involvement in Migration of Spermatogonial Cells

(2017) Mahmoud Huleihel et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Application of Quantitative Pharmacology Approaches in Bridging Pharmacokinetics and Pharmacodynamics of Domagrozumab From Adult Healthy Subjects to Pediatric Patients With Duchenne Muscular Disease

(2017) Indranil Bhattacharya et al.   JOURNAL OF CLINICAL PHARMACOLOGY

Ataluren in patients with nonsense mutation Duchenne muscular dystrophy (ACT DMD): a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial

(2017) Craig M McDonald et al.   LANCET

Progress toward Gene Therapy for Duchenne Muscular Dystrophy

(2017) Joel R. Chamberlain et al.   MOLECULAR THERAPY

A phase 3 randomized placebo-controlled trial of tadalafil for Duchenne muscular dystrophy

(2017) Ronald G. Victor et al.   NEUROLOGY

Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9

(2017) Dong Niu et al.   SCIENCE

FDA Approves Eteplirsen for Duchenne Muscular Dystrophy: The Next Chapter in the Eteplirsen Saga

(2017) Annemieke Aartsma-Rus et al.   Nucleic Acid Therapeutics

Intraperitoneal injection of microencapsulated Sertoli cells restores muscle morphology and performance in dystrophic mice

(2016) Sara Chiappalupi et al.   BIOMATERIALS

Terapeutic Potential of Microencapsulated Sertoli Cells in Huntington Disease

(2016) Giovanni Luca et al.   CNS Neuroscience & Therapeutics

Translational Pharmacokinetic/Pharmacodynamic Analysis of MYO-029 Antibody for Muscular Dystrophy

(2016) P Singh et al.   CTS-Clinical and Translational Science

Exon skipping: a first in class strategy for Duchenne muscular dystrophy

(2016) Erik H. Niks et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Idebenone reduces respiratory complications in patients with Duchenne muscular dystrophy

(2016) Craig M. McDonald et al.   NEUROMUSCULAR DISORDERS

Histological effects of givinostat in boys with Duchenne muscular dystrophy

(2016) Paolo Bettica et al.   NEUROMUSCULAR DISORDERS

Xenograft of microencapsulated Sertoli cells restores glucose homeostasis in db/db mice with spontaneous diabetes mellitus

(2016) Giovanni Luca et al.   XENOTRANSPLANTATION

Safety, Tolerability, and Pharmacokinetics of SMT C1100, a 2-Arylbenzoxazole Utrophin Modulator, following Single- and Multiple-Dose Administration to Pediatric Patients with Duchenne Muscular Dystrophy

(2016) Valeria Ricotti et al.   PLoS One

Intra-arterial transplantation of HLA-matched donor mesoangioblasts in Duchenne muscular dystrophy

(2015) G. Cossu et al.   EMBO Molecular Medicine

Safe and bodywide muscle transduction in young adult Duchenne muscular dystrophy dogs with adeno-associated virus

(2015) Yongping Yue et al.   HUMAN MOLECULAR GENETICS

The TREAT-NMD DMD Global Database: Analysis of More than 7,000 Duchenne Muscular Dystrophy Mutations

(2015) Catherine L. Bladen et al.   HUMAN MUTATION

Efficacy of idebenone on respiratory function in patients with Duchenne muscular dystrophy not using glucocorticoids (DELOS): a double-blind randomised placebo-controlled phase 3 trial

(2015) Gunnar M Buyse et al.   LANCET

Duchenne Muscular Dystrophy: From Diagnosis to Therapy

(2015) Maria Falzarano et al.   MOLECULES

In vivo gene editing in dystrophic mouse muscle and muscle stem cells

(2015) M. Tabebordbar et al.   SCIENCE

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

(2015) C. E. Nelson et al.   SCIENCE

Long-term stability, functional competence, and safety of microencapsulated specific pathogen-free neonatal porcine Sertoli cells: a potential product for cell transplant therapy

(2015) Giovanni Luca et al.   XENOTRANSPLANTATION

PW1/Peg3 expression regulates key properties that determine mesoangioblast stem cell competence

(2015) Chiara Bonfanti et al.   Nature Communications

Gene therapy for Duchenne muscular dystrophy

(2015) Julian Ramos et al.   Expert Opinion on Orphan Drugs

Halofuginone improves muscle-cell survival in muscular dystrophies

(2014) Anna Bodanovsky et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mouse Sertoli Cells Sustain De Novo Generation of Regulatory T Cells by Triggering the Notch Pathway Through Soluble JAGGED11

(2014) Antonio Francesco Campese et al.   BIOLOGY OF REPRODUCTION

Ataluren treatment of patients with nonsense mutation dystrophinopathy

(2014) Katharine Bushby et al.   MUSCLE & NERVE

PDE5 inhibition alleviates functional muscle ischemia in boys with Duchenne muscular dystrophy

(2014) M. D. Nelson et al.   NEUROLOGY

Sertoli cells – Immunological sentinels of spermatogenesis

(2014) Gurvinder Kaur et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Xenograft of Microencapsulated Sertoli Cells for the Cell Therapy of Type 2 Diabetes Mellitus in Spontaneously Diabetic Nonhuman Primates: Preliminary Data

(2014) G. Luca et al.   TRANSPLANTATION PROCEEDINGS

What Can We Learn From Clinical Trials of Exon Skipping for DMD?

(2014) Qi-long Lu et al.   Molecular Therapy-Nucleic Acids

VBP15, a novel anti-inflammatory and membrane-stabilizer, improves muscular dystrophy without side effects

(2013) Christopher R. Heier et al.   EMBO Molecular Medicine

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(2013) Silvia Consalvi et al.   MOLECULAR MEDICINE

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Prolongation of skin allograft survival in rats by the transplantation of microencapsulated xenogeneic neonatal porcine Sertoli cells

(2012) Giovanni Bistoni et al.   BIOMATERIALS

Human ES- and iPS-Derived Myogenic Progenitors Restore DYSTROPHIN and Improve Contractility upon Transplantation in Dystrophic Mice

(2012) Radbod Darabi et al.   Cell Stem Cell

Infection Barriers to Successful Xenotransplantation Focusing on Porcine Endogenous Retroviruses

(2012) J. Denner et al.   CLINICAL MICROBIOLOGY REVIEWS

Reversal of experimental Laron Syndrome by xenotransplantation of microencapsulated porcine Sertoli cells

(2012) Giovanni Luca et al.   JOURNAL OF CONTROLLED RELEASE

Gene and cell-mediated therapies for muscular dystrophy

(2012) Patryk Konieczny et al.   MUSCLE & NERVE

Effects of glucocorticoids and idebenone on respiratory function in patients with duchenne muscular dystrophy

(2012) Gunnar M. Buyse et al.   PEDIATRIC PULMONOLOGY

Correlation between insulin requirements and anti-galactose antibodies in patients with type 1 diabetes transplanted with neonatal pig islets

(2011) R. Esquivel-Pérez et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases

(2011) G. Basta et al.   DIABETES CARE

Rat resident testicular macrophages have an alternatively activated phenotype and constitutively produce interleukin-10 in vitro

(2011) W. R. Winnall et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Transplanted Myoblasts Can Migrate Several Millimeters to Fuse With Damaged Myofibers in Nonhuman Primate Skeletal Muscle

(2011) Daniel Skuk et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Current Status of Pharmaceutical and Genetic Therapeutic Approaches to Treat DMD

(2011) Christophe Pichavant et al.   MOLECULAR THERAPY

Phase 1 Gene Therapy for Duchenne Muscular Dystrophy Using a Translational Optimized AAV Vector

(2011) Dawn E Bowles et al.   MOLECULAR THERAPY

Immunological, paracrine and endocrine aspects of testicular immune privilege

(2010) Andreas Meinhardt et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Aromatase gene expression in immature rat Sertoli cells: age-related changes in the FSH signalling pathway

(2010) Hélène Bouraïma-Lelong et al.   REPRODUCTION FERTILITY AND DEVELOPMENT

Xenograft of Microencapsulated Sertoli Cells Reverses T1DM in NOD Mice by Inducing Neogenesis of Beta-Cells

(2010) Giovanni Luca et al.   TRANSPLANTATION

Theoretic applicability of antisense-mediated exon skipping for Duchenne muscular dystrophy mutations

(2009) Annemieke Aartsma-Rus et al.   HUMAN MUTATION

Therapy of experimental type 1 diabetes by isolated Sertoli cell xenografts alone

(2009) Francesca Fallarino et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cell-mediated Immunomodulation of Chemokine Receptor 7–expressing Porcine Sertoli Cells in Murine Heterotopic Heart Transplantation

(2009) Hong-Gook Lim et al.   JOURNAL OF HEART AND LUNG TRANSPLANTATION

No evidence of porcine endogenous retrovirus in patients with type 1 diabetes after long-term porcine islet xenotransplantation

(2009) Rafael Valdes-Gonzalez et al.   JOURNAL OF MEDICAL VIROLOGY

Immunoprotective Sertoli cells: making allogeneic and xenogeneic transplantation feasible

(2009) Payal Mital et al.   REPRODUCTION

Endogenous retroviruses

(2008) C. A. Wilson   CELLULAR AND MOLECULAR LIFE SCIENCES

HDAC2 blockade by nitric oxide and histone deacetylase inhibitors reveals a common target in Duchenne muscular dystrophy treatment

(2008) C. Colussi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA