Blockade of ALK4/5 signaling suppresses cadmium- and erastin-induced cell death in renal proximal tubular epithelial cells via distinct signaling mechanisms

Heme oxygenase-1 mediates BAY 11–7085 induced ferroptosis

(2018) Ling-Chu Chang et al.   CANCER LETTERS

RGMb protects against acute kidney injury by inhibiting tubular cell necroptosis via an MLKL-dependent mechanism

(2018) Wenjing Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Human renal tubular cells contain CD24/CD133 progenitor cell populations: Implications for tubular regeneration after toxicant induced damage using cadmium as a model

(2017) Swojani Shrestha et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis

(2017) Z Fan et al.   Oncogenesis

From the Cover: Autophagy Induction Contributes to Cadmium Toxicity in Mesenchymal Stem Cells via AMPK/FOXO3a/BECN1 Signaling

(2016) Min Yang et al.   TOXICOLOGICAL SCIENCES

RSL3 and Erastin differentially regulate redox signaling to promote Smac mimetic-induced cell death

(2016) Jasmin Dächert et al.   Oncotarget

Erastin Disrupts Mitochondrial Permeability Transition Pore (mPTP) and Induces Apoptotic Death of Colorectal Cancer Cells

(2016) Haizhong Huo et al.   PLoS One

Caspase-Dependent and Caspase-Independent Pathways Are Involved in Cadmium-Induced Apoptosis in Primary Rat Proximal Tubular Cell Culture

(2016) Gang Liu et al.   PLoS One

Glutathione peroxidase 4 prevents necroptosis in mouse erythroid precursors

(2015) O. Canli et al.   BLOOD

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

(2015) Xiaofang Sun et al.   HEPATOLOGY

Role of Glutathione Peroxidase 4 in Conjunctival Epithelial Cells

(2015) O. Sakai et al.   INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE

A Role for Tubular Necroptosis in Cisplatin-Induced AKI

(2015) Y. Xu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Endothelial mitochondrial oxidative stress determines podocyte depletion in segmental glomerulosclerosis

(2014) Ilse Daehn et al.   JOURNAL OF CLINICAL INVESTIGATION

Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models

(2014) Rachid Skouta et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Inhibitory Role of the KEAP1-NRF2 Pathway in TGFβ1-Stimulated Renal Epithelial Transition to Fibroblastic Cells: A Modulatory Effect on SMAD Signaling

(2014) In-geun Ryoo et al.   PLoS One

Synchronized renal tubular cell death involves ferroptosis

(2014) Andreas Linkermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Detrimental effects of Notch1 signaling activated by cadmium in renal proximal tubular epithelial cells

(2014) K Fujiki et al.   Cell Death & Disease

Phosphorylation of FOXO3a by PI3K/Akt pathway in HK-2 renal proximal tubular epithelial cells exposed to cadmium

(2013) Kota Fujiki et al.   ARCHIVES OF TOXICOLOGY

Epithelial Cell TGF  Signaling Induces Acute Tubular Injury and Interstitial Inflammation

(2013) M. E. Gentle et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Effect of Cadmium on Lipid Peroxidation and on Some Antioxidants in the Liver, Kidneys and Testes of Rats Given Diet Containing Cadmium-polluted Radish Bulbs

(2013) Samir Haouem et al.   Journal of Toxicologic Pathology

Cadmium induced Drp1-dependent mitochondrial fragmentation by disturbing calcium homeostasis in its hepatotoxicity

(2013) S Xu et al.   Cell Death & Disease

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Mixed Lineage Kinase Domain-like Protein Mediates Necrosis Signaling Downstream of RIP3 Kinase

(2012) Liming Sun et al.   CELL

The Akt-FoxO3a-manganese superoxide dismutase pathway is involved in the regulation of oxidative stress in diabetic nephropathy

(2012) Qian Lu et al.   EXPERIMENTAL PHYSIOLOGY

Gpx4 ablation in adult mice results in a lethal phenotype accompanied by neuronal loss in brain

(2012) Si-Eun Yoo et al.   FREE RADICAL BIOLOGY AND MEDICINE

Expression of RASSF6 in kidney and the implication of RASSF6 and the Hippo pathway in the sorbitol-induced apoptosis in renal proximal tubular epithelial cells

(2012) K. Withanage et al.   JOURNAL OF BIOCHEMISTRY

Response gene to complement 32 interacts with Smad3 to promote epithelial-mesenchymal transition of human renal tubular cells

(2011) Xia Guo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

EGF Receptor Exposed to Oxidative Stress Acquires Abnormal Phosphorylation and Aberrant Activated Conformation That Impairs Canonical Dimerization

(2011) Simone Filosto et al.   PLoS One

NecroX as a novel class of mitochondrial reactive oxygen species and ONOO− scavenger

(2010) Hyoung Jin Kim et al.   ARCHIVES OF PHARMACAL RESEARCH

Smad2 Protects against TGF- /Smad3-Mediated Renal Fibrosis

(2010) X. M. Meng et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

NAD(P)H Oxidase Mediates TGF- 1-Induced Activation of Kidney Myofibroblasts

(2009) C. D. Bondi et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Activin A: Autocrine Regulator of Kidney Development and Repair

(2008) Akito MAESHIMA et al.   ENDOCRINE JOURNAL

MAPK and mTOR pathways are involved in cadmium-induced neuronal apoptosis

(2008) Long Chen et al.   JOURNAL OF NEUROCHEMISTRY

Epidermal growth factor receptor exposed to cigarette smoke is aberrantly activated and undergoes perinuclear trafficking

(2007) Elaine M. Khan et al.   FASEB JOURNAL