The medicinal leech as a valuable model for better understanding the role of a TLR4-like receptor in the inflammatory process

An annotated CNS transcriptome of the medicinal leech, Hirudo verbana: De novo sequencing to characterize genes associated with nervous system activity

(2018) Adam J. Northcutt et al.   PLoS One

AIF-1 and RNASET2 Play Complementary Roles in the Innate Immune Response of Medicinal Leech

(2018) Nicolò Baranzini et al.   Journal of Innate Immunity

Cellular responses induced by multi-walled carbon nanotubes: in vivo and in vitro studies on the medicinal leech macrophages

(2017) Rossana Girardello et al.   Scientific Reports

The Role of Toll-Like Receptor 4 in Infectious and Noninfectious Inflammation

(2016) Monica Molteni et al.   MEDIATORS OF INFLAMMATION

Hm-MyD88 and Hm-SARM: Two key regulators of the neuroimmune system and neural repair in the medicinal leech

(2015) F. Rodet et al.   Scientific Reports

Effects of Carbon Nanotube Environmental Dispersion on an Aquatic Invertebrate, Hirudo medicinalis

(2015) Rossana Girardello et al.   PLoS One

Homolog of allograft inflammatory factor-1 induces macrophage migration during innate immune response in leech

(2014) Tilo Schorn et al.   CELL AND TISSUE RESEARCH

Microglia of medicinal leech (Hirudo medicinalis) express a specific activation marker homologous to vertebrate ionized calcium-binding adapter molecule 1 (Iba1/alias aif-1)

(2014) Francesco Drago et al.   Developmental Neurobiology

Integrin CD11b positively regulates TLR4-induced signalling pathways in dendritic cells but not in macrophages

(2014) Guang Sheng Ling et al.   Nature Communications

Sweeten PAMPs: role of sugar complexed PAMPs in innate immunity and vaccine biology

(2013) Ranjeet Singh Mahla   Frontiers in Immunology

Clinical uses of the medicinal leech: A practical review

(2011) SPA Stawicki et al.   Journal of Postgraduate Medicine

Cytokine Loaded Biopolymers as a Novel Strategy to Study Stem Cells during Wound-Healing Processes

(2011) Annalisa Grimaldi et al.   MACROMOLECULAR BIOSCIENCE

Construction of a medicinal leech transcriptome database and its application to the identification of leech homologs of neural and innate immune genes

(2010) Eduardo R Macagno et al.   BMC GENOMICS

The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors

(2010) Taro Kawai et al.   NATURE IMMUNOLOGY

Deciphering the Immune Function and Regulation by a TLR of the Cytokine EMAPII in the Lesioned Central Nervous System Using a Leech Model

(2009) D. Schikorski et al.   JOURNAL OF IMMUNOLOGY

Cyanobacterial LPS antagonist (CyP)—A novel and efficient inhibitor of Escherichia coli LPS-induced cytokine response in the pig

(2008) Ebbe Billmann Thorgersen et al.   MOLECULAR IMMUNOLOGY

Toll-like receptor genes (TLRs) from Capitella capitata and Helobdella robusta (Annelida)

(2007) Charis R. Davidson et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY