Tumour necrosis factor superfamily members in ischaemic vascular diseases

Immunomodulatory interventions in myocardial infarction and heart failure: a systematic review of clinical trials and meta-analysis of IL-1 inhibition

(2018) Mona Panahi et al.   CARDIOVASCULAR RESEARCH

Cardiovascular outcomes of patients with rheumatoid arthritis prescribed disease modifying anti-rheumatic drugs: a review

(2018) Alessandro Giollo et al.   Expert Opinion On Drug Safety

TRAIL protects against endothelial dysfunction in vivo and inhibits angiotensin-II-induced oxidative stress in vascular endothelial cells in vitro

(2018) Pradeep Manuneedhi Cholan et al.   FREE RADICAL BIOLOGY AND MEDICINE

Phase I Study of Enavatuzumab, a First-in-Class Humanized Monoclonal Antibody Targeting the TWEAK Receptor, in Patients with Advanced Solid Tumors

(2017) Elaine T. Lam et al.   MOLECULAR CANCER THERAPEUTICS

TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice

(2017) Valvanera Fernández-Laso et al.   Scientific Reports

Non-alcoholic fatty liver disease, vascular inflammation and insulin resistance are exacerbated by TRAIL deletion in mice

(2017) Siân P. Cartland et al.   Scientific Reports

Response to biological treatment and subsequent risk of coronary events in rheumatoid arthritis

(2016) Lotta Ljung et al.   ANNALS OF THE RHEUMATIC DISEASES

Calcification of vascular smooth muscle cells is induced by secondary calciprotein particles and enhanced by tumor necrosis factor-α

(2016) Parisa Aghagolzadeh et al.   ATHEROSCLEROSIS

CD40 in coronary artery disease: a matter of macrophages?

(2016) Matthijs F. Jansen et al.   BASIC RESEARCH IN CARDIOLOGY

Population pharmacokinetic and pharmacodynamic analysis of BIIB023, an anti-TNF-like weak inducer of apoptosis (anti-TWEAK) monoclonal antibody

(2016) Gerald R. Galluppi et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Onto better TRAILs for cancer treatment

(2016) D de Miguel et al.   CELL DEATH AND DIFFERENTIATION

Soluble TWEAK and Major Adverse Cardiovascular Events in Patients with CKD

(2016) V. Fernandez-Laso et al.   Clinical Journal of the American Society of Nephrology

TWEAK favors phosphate-induced calcification of vascular smooth muscle cells through canonical and non-canonical activation of NFκB

(2016) L Hénaut et al.   Cell Death & Disease

Excess TNF-α in the blood activates monocytes with the potential to directly form cholesteryl ester-laden cells

(2015) Ming Zhu et al.   ACTA BIOCHIMICA ET BIOPHYSICA SINICA

The effects of tumour necrosis factor inhibitors, methotrexate, non-steroidal anti-inflammatory drugs and corticosteroids on cardiovascular events in rheumatoid arthritis, psoriasis and psoriatic arthritis: a systematic review and meta-analysis

(2015) Camille Roubille et al.   ANNALS OF THE RHEUMATIC DISEASES

Glatiramer acetate (GA) prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway

(2015) Guoqian Wei et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Soluble CD40 Ligand Promotes Macrophage Foam Cell Formation in the Etiology of Atherosclerosis

(2015) Ming Yuan et al.   CARDIOLOGY

The association of bone and osteoclasts with vascular calcification

(2015) Kum Hyun Han et al.   VASCULAR MEDICINE

Tumor Necrosis Factor-Related Apoptosis-Inducing Ligand (TRAIL) Promotes Angiogenesis and Ischemia-Induced Neovascularization Via NADPH Oxidase 4 (NOX4) and Nitric Oxide-Dependent Mechanisms

(2015) B. A. Di Bartolo et al.   Journal of the American Heart Association

SAT0140 The risk of acute coronary syndromes in RA in relation to TNF inhibitors and risks in the general population: A national cohort study

(2014) L. Ljung et al.   ANNALS OF THE RHEUMATIC DISEASES

TNF-α promotes early atherosclerosis by increasing transcytosis of LDL across endothelial cells: Crosstalk between NF-κB and PPAR-γ

(2014) Youzhi Zhang et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

HMGB1 Expression and Secretion Are Increased Via TWEAK–Fn14 Interaction in Atherosclerotic Plaques and Cultured Monocytes

(2013) Juan A. Moreno et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Inflammatory cytokines and risk of coronary heart disease: new prospective study and updated meta-analysis

(2013) S. Kaptoge et al.   EUROPEAN HEART JOURNAL

TRAIL-Deficiency Accelerates Vascular Calcification in Atherosclerosis via Modulation of RANKL

(2013) Belinda A. Di Bartolo et al.   PLoS One

TNF-related apoptosis-inducing ligand (TRAIL) protects against diabetes and atherosclerosis in Apoe −/− mice

(2011) B. A. Di Bartolo et al.   DIABETOLOGIA

Crosstalk in NF-κB signaling pathways

(2011) Andrea Oeckinghaus et al.   NATURE IMMUNOLOGY

Association of tumor necrosis factor-related apoptosis-inducing ligand with total and cardiovascular mortality in older adults

(2010) Stefano Volpato et al.   ATHEROSCLEROSIS

TRAIL Promotes VSMC Proliferation and Neointima Formation in a FGF-2–, Sp1 Phosphorylation–, and NFκB-Dependent Manner

(2010) Jeffrey Chan et al.   CIRCULATION RESEARCH

Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile

(2010) Esther Lutgens et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Systematic review and meta-analysis: Anti-tumor necrosis factor α therapy and cardiovascular events in rheumatoid arthritis

(2010) Cheryl Barnabe et al.   ARTHRITIS CARE & RESEARCH

Fn14-Fc Fusion Protein Regulates Atherosclerosis in ApoE −/− Mice and Inhibits Macrophage Lipid Uptake In Vitro

(2009) Kitty Schapira et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular mechanism and function of CD40/CD40L engagement in the immune system

(2009) Raul Elgueta et al.   IMMUNOLOGICAL REVIEWS

TNF-Like Weak Inducer of Apoptosis (TWEAK) Activates Proinflammatory Signaling Pathways and Gene Expression through the Activation of TGF- -Activated Kinase 1

(2009) M. Kumar et al.   JOURNAL OF IMMUNOLOGY

TNF-alpha stimulates the ACAT1 expression in differentiating monocytes to promote the CE-laden cell formation

(2009) Lei Lei et al.   JOURNAL OF LIPID RESEARCH

Tumor necrosis factor-alpha deficiency retards early fatty-streak lesion by influencing the expression of inflammatory factors in apoE-null mice

(2009) Ning Xiao et al.   MOLECULAR GENETICS AND METABOLISM

Absence of p55 TNF Receptor Reduces Atherosclerosis, but Has No Major Effect on Angiotensin II Induced Aneurysms in LDL Receptor Deficient Mice

(2009) Sofia Xanthoulea et al.   PLoS One

Plasma concentrations of TNF-α and its soluble receptors sTNFR1 and sTNFR2 in patients with coronary artery disease

(2009) K. Safranow et al.   TISSUE ANTIGENS

Death Receptors and Their Ligands in Atherosclerosis

(2008) Mary M. Kavurma et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells

(2008) C. Chen et al.   BLOOD

Chronic Apoptosis of Vascular Smooth Muscle Cells Accelerates Atherosclerosis and Promotes Calcification and Medial Degeneration

(2008) Murray C.H. Clarke et al.   CIRCULATION RESEARCH

Arterial calcification: a tumor necrosis factor-alpha mediated vascular Wnt-opathy

(2008) Ziyad Al-Aly   Translational Research

Expression, regulation and function of trail in atherosclerosis

(2007) Mary M. Kavurma et al.   BIOCHEMICAL PHARMACOLOGY