TWEAK blockade decreases atherosclerotic lesion size and progression through suppression of STAT1 signaling in diabetic mice

Vascular smooth muscle cell in atherosclerosis

(2015) D. A. Chistiakov et al.   Acta Physiologica

Gene delivery of suppressors of cytokine signaling (SOCS) inhibits inflammation and atherosclerosis development in mice

(2015) Carlota Recio et al.   BASIC RESEARCH IN CARDIOLOGY

TWEAK/Fn14 interaction promotes oxidative stress through NADPH oxidase activation in macrophages

(2015) Julio Madrigal-Matute et al.   CARDIOVASCULAR RESEARCH

Elevated levels of TWEAK in skeletal muscle promote visceral obesity, insulin resistance, and metabolic dysfunction

(2015) Shuichi Sato et al.   FASEB JOURNAL

Suppressor of Cytokine Signaling 1–Derived Peptide Inhibits Janus Kinase/Signal Transducers and Activators of Transcription Pathway and Improves Inflammation and Atherosclerosis in Diabetic Mice

(2014) Carlota Recio et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Genetic deletion or TWEAK blocking antibody administration reduce atherosclerosis and enhance plaque stability in mice

(2014) Cristina Sastre et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Deletion of TNF-like weak inducer of apoptosis (TWEAK) protects mice from adipose and systemic impacts of severe obesity

(2014) Grace Bennett et al.   Obesity

Tumor Necrosis Factor‐Like Weak Inducer of Apoptosis or Fn14 Deficiency Reduce Elastase Perfusion‐Induced Aortic Abdominal Aneurysm in Mice

(2014) Carlos Tarín et al.   Journal of the American Heart Association

TWEAK/Fn14 Axis: A Promising Target for the Treatment of Cardiovascular Diseases

(2014) Luis M. Blanco-Colio   Frontiers in Immunology

HMGB1 Expression and Secretion Are Increased Via TWEAK–Fn14 Interaction in Atherosclerotic Plaques and Cultured Monocytes

(2013) Juan A. Moreno et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Animal Models of Atherosclerosis

(2012) Godfrey S. Getz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TWEAK signals through JAK–STAT to induce tumor cell apoptosis

(2012) Mark S. Chapman et al.   CYTOKINE

Biology and significance of the JAK/STAT signalling pathways

(2012) Hiu Kiu et al.   GROWTH FACTORS

Fc  Receptor Deficiency Attenuates Diabetic Nephropathy

(2012) V. Lopez-Parra et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Serum Levels of TWEAK and Scavenger Receptor CD163 in Type 1 Diabetes Mellitus: Relationship with Cardiovascular Risk Factors. A Case-Control Study

(2012) Gemma Llauradó et al.   PLoS One

OxLDL up-regulates microRNA-29b, leading to epigenetic modifications of MMP-2/MMP-9 genes: a novel mechanism for cardiovascular diseases

(2011) Ku-Chung Chen et al.   FASEB JOURNAL

Peripheral Artery Disease Is Associated With a High CD163/TWEAK Plasma Ratio

(2010) Juan A. Moreno et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

TWEAK-Fn14 interaction enhances plasminogen activator inhibitor 1 and tissue factor expression in atherosclerotic plaques and in cultured vascular smooth muscle cells

(2010) B. Munoz-Garcia et al.   CARDIOVASCULAR RESEARCH

Fn14-Fc Fusion Protein Regulates Atherosclerosis in ApoE −/− Mice and Inhibits Macrophage Lipid Uptake In Vitro

(2009) Kitty Schapira et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Tumor Necrosis Factor–Like Weak Inducer of Apoptosis (TWEAK) Enhances Vascular and Renal Damage Induced by Hyperlipidemic Diet in ApoE-Knockout Mice

(2009) Begoña Muñoz-García et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Suppressors of Cytokine Signaling Modulate JAK/STAT-Mediated Cell Responses During Atherosclerosis

(2009) Guadalupe Ortiz-Muñoz et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Signal Transducer and Activator of Transcription-1 Is Critical for Apoptosis in Macrophages Subjected to Endoplasmic Reticulum Stress In Vitro and in Advanced Atherosclerotic Lesions In Vivo

(2008) Wah-Seng Lim et al.   CIRCULATION

The TWEAK–Fn14 cytokine–receptor axis: discovery, biology and therapeutic targeting

(2008) Jeffrey A. Winkles   NATURE REVIEWS DRUG DISCOVERY