FoxO1 inhibits autophagosome-lysosome fusion leading to endothelial autophagic-apoptosis in diabetes

The regulation of FOXO1 and its role in disease progression

(2018) Ya-qi Xing et al.   LIFE SCIENCES

Macro- and microvascular endothelial dysfunction in diabetes

(2017) Yi Shi et al.   Journal of Diabetes

Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling

(2016) Jessica L. Fetterman et al.   ATHEROSCLEROSIS

FOXO1 couples metabolic activity and growth state in the vascular endothelium

(2016) Kerstin Wilhelm et al.   NATURE

LAMP-2 is required for incorporating syntaxin-17 into autophagosomes and for their fusion with lysosomes

(2016) Virginie Hubert et al.   Biology Open

ATG14 controls SNARE-mediated autophagosome fusion with a lysosome

(2015) Rong Liu et al.   Autophagy

ATG14 promotes membrane tethering and fusion of autophagosomes to endolysosomes

(2015) Jiajie Diao et al.   NATURE

Autophagy and apoptosis: where do they meet?

(2014) Subhadip Mukhopadhyay et al.   APOPTOSIS

Genetic polymorphisms at SIRT1 and FOXO1 are associated with carotid atherosclerosis in the SAPHIR cohort

(2014) Lyudmyla Kedenko et al.   BMC Medical Genetics

Impairment of autophagy in endothelial cells prevents shear-stress-induced increases in nitric oxide bioavailability

(2014) Leena P. Bharath et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Autophagy Protects Against Senescence and Apoptosis via the RAS-Mitochondria in High-Glucose-Induced Endothelial Cells

(2014) Fei Chen et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

FOXO1-Mediated Activation of Akt Plays a Critical Role in Vascular Homeostasis

(2014) Harita Dharaneeswaran et al.   CIRCULATION RESEARCH

Syntaxin 17

(2013) Eisuke Itakura et al.   Autophagy

Advanced glycation end-products induce endoplasmic reticulum stress in human aortic endothelial cells

(2013) Christos Adamopoulos et al.   CLINICAL CHEMISTRY AND LABORATORY MEDICINE

Lysosome Dysfunction Enhances Oxidative Stress-Induced Apoptosis through Ubiquitinated Protein Accumulation in Hela Cells

(2012) Chunyan Yu et al.   Anatomical Record-Advances in Integrative Anatomy and Evolutionary Biology

AMPK Promotes p53 Acetylation via Phosphorylation and Inactivation of SIRT1 in Liver Cancer Cells

(2012) C.-W. Lee et al.   CANCER RESEARCH

FOXOs and Sirtuins in Vascular Growth, Maintenance, and Aging

(2012) Mark F. Oellerich et al.   CIRCULATION RESEARCH

The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism

(2012) Xiwen Xiong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXO1 Mediates the Autocrine Effect of Endothelin-1 on Endothelial Cell Survival

(2012) Vincenza Cifarelli et al.   MOLECULAR ENDOCRINOLOGY

The diverse ligand repertoire of the receptor for advanced glycation endproducts and pathways to the complications of diabetes

(2012) Ravichandran Ramasamy et al.   VASCULAR PHARMACOLOGY

Autophagy: Renovation of Cells and Tissues

(2011) Noboru Mizushima et al.   CELL

Rab7: Role of its protein interaction cascades in endo-lysosomal traffic

(2010) Tuanlao Wang et al.   CELLULAR SIGNALLING

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

The role of autophagy-lysosome pathway in neurodegeneration associated with Parkinson's disease

(2008) T. Pan et al.   BRAIN