The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism

Curcumin induces autophagy to protect vascular endothelial cell survival from oxidative stress damage

(2012) Jing Han et al.   Autophagy

Targeting the UPR transcription factor XBP1 protects against Huntington's disease through the regulation of FoxO1 and autophagy

(2012) Rene L. Vidal et al.   HUMAN MOLECULAR GENETICS

Thyroid hormone stimulates hepatic lipid catabolism via activation of autophagy

(2012) Rohit Anthony Sinha et al.   JOURNAL OF CLINICAL INVESTIGATION

Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets

(2012) Anoop Kumar G. Velikkakath et al.   MOLECULAR BIOLOGY OF THE CELL

Modulation of glutamine metabolism by the PI(3)K–PKB–FOXO network regulates autophagy

(2012) Kristan E. van der Vos et al.   NATURE CELL BIOLOGY

p62/SQSTM1/A170: Physiology and pathology

(2012) Masaaki Komatsu et al.   PHARMACOLOGICAL RESEARCH

Class III PI3K Vps34 plays an essential role in autophagy and in heart and liver function

(2012) N. Jaber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JNK modulates FOXO3a for the expression of the mitochondrial death and mitophagy marker BNIP3 in pathological hypertrophy and in heart failure

(2012) A H Chaanine et al.   Cell Death & Disease

Selective taste of ethanol-induced autophagy for mitochondria and lipid droplets

(2011) Wen-Xing Ding et al.   Autophagy

The coiled-coil domain protein EPG-8 plays an essential role in the autophagy pathway inC. elegans

(2011) Peiguo Yang et al.   Autophagy

FoxO3 hastens autophagy and shrinks the heart but does not curtail pathological hypertrophy in adult mice

(2011) X. Wang et al.   CARDIOVASCULAR RESEARCH

FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model

(2011) Tobias G. Schips et al.   CARDIOVASCULAR RESEARCH

Autophagy and Aging

(2011) David C. Rubinsztein et al.   CELL

Temporal orchestration of circadian autophagy rhythm by C/EBPβ

(2011) Di Ma et al.   EMBO JOURNAL

JNK regulates FoxO-dependent autophagy in neurons

(2011) P. Xu et al.   GENES & DEVELOPMENT

Hepatic FoxOs Regulate Lipid Metabolism via Modulation of Expression of the Nicotinamide Phosphoribosyltransferase Gene

(2011) Rongya Tao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

AMPK promotes skeletal muscle autophagy through activation of forkhead FoxO3a and interaction with Ulk1

(2011) Anthony MJ Sanchez et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

IRS2 increases mitochondrial dysfunction and oxidative stress in a mouse model of Huntington disease

(2011) Marianna Sadagurski et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagosome targeting and membrane curvature sensing by Barkor/Atg14(L)

(2011) W. Fan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Defective Hepatic Autophagy in Obesity Promotes ER Stress and Causes Insulin Resistance

(2010) Ling Yang et al.   Cell Metabolism

Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes

(2010) Nirmala Hariharan et al.   CIRCULATION RESEARCH

A Genome-Wide siRNA Screen Reveals Multiple mTORC1 Independent Signaling Pathways Regulating Autophagy under Normal Nutritional Conditions

(2010) Marta M. Lipinski et al.   DEVELOPMENTAL CELL

Autophagy Reduces Acute Ethanol-Induced Hepatotoxicity and Steatosis in Mice

(2010) Wen–Xing Ding et al.   GASTROENTEROLOGY

FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress

(2010) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Autophagy requires endoplasmic reticulum targeting of the PI3-kinase complex via Atg14L

(2010) Kohichi Matsunaga et al.   JOURNAL OF CELL BIOLOGY

Calorie restriction enhances cell adaptation to hypoxia through Sirt1-dependent mitochondrial autophagy in mouse aged kidney

(2010) Shinji Kume et al.   JOURNAL OF CLINICAL INVESTIGATION

Deficiency of the Transcriptional Regulator p8 Results in Increased Autophagy and Apoptosis, and Causes Impaired Heart Function

(2010) Derek K. Kong et al.   MOLECULAR BIOLOGY OF THE CELL

Cytosolic FoxO1 is essential for the induction of autophagy and tumour suppressor activity

(2010) Ying Zhao et al.   NATURE CELL BIOLOGY

Eaten alive: a history of macroautophagy

(2010) Zhifen Yang et al.   NATURE CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

IKK-dependent, NF-κB-independent control of autophagic gene expression

(2010) W C Comb et al.   ONCOGENE

p38α blockade inhibits colorectal cancer growth in vivo by inducing a switch from HIF1α- to FoxO-dependent transcription

(2009) F Chiacchiera et al.   CELL DEATH AND DIFFERENTIATION

Mammalian autophagy: core molecular machinery and signaling regulation

(2009) Zhifen Yang et al.   CURRENT OPINION IN CELL BIOLOGY

Lipophagy: Selective Catabolism Designed for Lipids

(2009) Hilla Weidberg et al.   DEVELOPMENTAL CELL

Hepatic Autophagy Is Suppressed in the Presence of Insulin Resistance and Hyperinsulinemia

(2009) Hui-Yu Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FoxO Transcription Factors Promote Autophagy in Cardiomyocytes

(2009) Arunima Sengupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ID2 (Inhibitor of DNA Binding 2) Is a Rhythmically Expressed Transcriptional Repressor Required for Circadian Clock Output in Mouse Liver

(2009) Tim Y. Hou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5

(2009) Kasper M.A. Rouschop et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy regulates lipid metabolism

(2009) Rajat Singh et al.   NATURE

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1–phosphatidylinositol-3-kinase complex

(2009) Yun Zhong et al.   NATURE CELL BIOLOGY

Beclin 1 Forms Two Distinct Phosphatidylinositol 3-Kinase Complexes with Mammalian Atg14 and UVRAG

(2008) Eisuke Itakura et al.   MOLECULAR BIOLOGY OF THE CELL

E2F1 regulates autophagy and the transcription of autophagy genes

(2008) S Polager et al.   ONCOGENE

Identification of Barkor as a mammalian autophagy-specific factor for Beclin 1 and class III phosphatidylinositol 3-kinase

(2008) Q. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA