Article
Chemistry, Applied
Ce Gao, Xue-Lian Wang, Qing-Da An, Zuo-Yi Xiao, Shang-Ru Zhai
Summary: A new aerogel with superior mechanical properties, high adsorption capacity, and excellent regeneration property has been developed for heavy metal removal from water. The alginate/melamine/chitosan aerogel efficiently extracts Pb(II) from aqueous solution, showing excellent and selective adsorption capacity, and can be regenerated using dilute acidic solution.
CARBOHYDRATE POLYMERS
(2021)
Article
Biochemistry & Molecular Biology
Norhazirah Rosli, Wan Zaireen Nisa Yahya, Mohd Dzul Hakim Wirzal
Summary: Nanostructure adsorbents, specifically nanofiber membranes made of chitosan/PVA blend, were successfully synthesized through electrospinning and functionalization methods to act as potential bio-sorbents for heavy metal ions removal. The synthesized adsorbent showed excellent performance in removing Pb(II) ions from pure heavy metal ions solutions, with a high adsorption capacity and compatibility with the Freundlich isotherm and pseudo-second-order kinetic models.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Environmental Sciences
Sara Ranjbari, Ali Ayati, Bahareh Tanhaei, Amani Al-Othman, Fatemeh Karimi
Summary: In this study, bi-functionalized chitosan beads were successfully prepared and used for the efficient removal of anionic food dye from polluted water. The experimental data showed high adsorption efficiency, fitting well with the pseudo-first-order kinetic model and the Langmuir isotherm model under optimal conditions. The conjugation of chitosan beads with surfactant and ionic liquid introduced a new type of adsorbents for wastewater treatment.
ENVIRONMENTAL RESEARCH
(2022)
Article
Biochemistry & Molecular Biology
A. Dzieniszewska, J. Nowicki, G. Rzepa, J. Kyziol-Komosinska, I. Semeniuk, D. Kie Lkiewicz, J. Czupio
Summary: This study prepared novel biosorbents based on chitosan and imidazolium ionic liquid for the removal of fluoride from aqueous solutions. Experimental results showed that the introduction of ionic liquid significantly improved the adsorption performance of fluoride, and the adsorption was influenced by the experimental conditions and the method of ionic liquid synthesis.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Analytical
Takaaki Tatsumi, Yoshiro Tahara, Michiaki Matsumoto
Summary: The study prepared adsorbents consisting of chitosan modified with amidoxime groups and cellulose with the use of an ionic liquid, leading to improved metal adsorptivity and gel stability. The adsorption characteristics of these amidoxime-chitosan/cellulose hydrogels showed high physical stability and selectivity towards copper ions when compared to other metals. The results suggest that these environmentally benign adsorbents have promising potential for metal ion recovery in aqueous media.
Article
Biochemistry & Molecular Biology
Tongyao Zhao, Xiaoyan Li, Yumei Gong, Yanzhu Guo, Fengyu Quan, Qiang Shi
Summary: The study focused on the binary blending of sodium alginate and quaternary ammonium chitosan to fabricate composite fibers. The results showed changes in solution state and electrical potential at different mass ratios, leading to the production of fibers with excellent properties.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Environmental Sciences
Hassan Karimi-Maleh, Sara Ranjbari, Bahareh Tanhaei, Ali Ayati, Yasin Orooji, Marzieh Alizadeh, Fatemeh Karimi, Sadegh Salmanpour, Jalal Rouhi, Mika Sillanpaa, Fatih Sen
Summary: The study revealed that BmImBr impregnated chitosan beads showed efficient removal of methylene blue, reaching 86% removal efficiency in just 25 minutes. Increasing the amount of BmImBr improved the adsorption performance of the prepared beads.
ENVIRONMENTAL RESEARCH
(2021)
Article
Engineering, Environmental
Nooraddein A. Ekrayem, Almahdi A. Alhwaige, Wael Elhrari, Mohamed Amer
Summary: The study developed eco-friendly polymeric spheres derived from crosslinking of chitosan (CTS) with different polyesters. The spheres showed enhanced structure and stability in aqueous media, with decreased hydrophilicity, and were effective in adsorbing lead ions (Pb2+) from aqueous solutions. The experimental data was fitted well with the Freundlich isotherm model, showing the best fit for the adsorption process.
JOURNAL OF ENVIRONMENTAL CHEMICAL ENGINEERING
(2021)
Article
Green & Sustainable Science & Technology
M. N. Khan, M. Chowdhury, M. M. Rahman
Summary: A 3D composite aerogel prepared from dodecyl amine modified clay enriched chitosan/alginate showed high thermal stability and significant adsorption capacities for methylene blue, acid black, and hexavalent chromium ions, demonstrating potential for wastewater treatment.
MATERIALS TODAY SUSTAINABILITY
(2021)
Article
Chemistry, Physical
Yashvi Sheth, Swapnil Dharaskar, Mohammad Khalid, Rashmi Walvekar
Summary: A novel composite adsorptive film was prepared in this study by modifying chitosan with 1butyl-3-methylimidazolium acetate (Chitosan-[BMIM][OAc]). The film demonstrated excellent removal efficiency and fast kinetics for Cr(VI) removal from contaminated water.
JOURNAL OF MOLECULAR LIQUIDS
(2022)
Article
Biochemistry & Molecular Biology
Jinming Ma, Meng Zhang, Miaomiao Ji, Lexin Zhang, Zhihui Qin, Yaru Zhang, Lili Gao, Tifeng Jiao
Summary: A novel magnetic gel bead adsorbent was developed using graphene oxide modified Fe3O4, showing high adsorption capacity for various cationic dyes and excellent recyclability with over 90% removal rates after five recycles. This strategy provides a promising approach for preparing efficient and recyclable cationic dye adsorbents with large specific surface areas.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Chemistry, Physical
Ismaila Olalekan Saheed, Wen -Da Oh, Faiz Bukhari Mohd Suah
Summary: This study investigated the removal of hydrophilic imidazolium-based ionic liquid from aqueous solution using chitosan-activated carbon composite (CH-AC). The experimental data analyzed using Langmuir and Freundlich isotherms fitted best into Langmuir model, and the adsorption capacity of CH-AC for [BMIM][Br] was calculated to be 12.17 mg/g. Adsorption kinetics fitted into pseudo-second order model.
COLLOID AND INTERFACE SCIENCE COMMUNICATIONS
(2021)
Article
Biochemistry & Molecular Biology
Maithili A. Khapre, Sadanand Pandey, Ravin M. Jugade
Summary: A novel composite material was synthesized using glutaraldehyde as cross-linking agent for potential dye adsorption, exhibiting thermodynamically and spontaneous adsorption behavior. The synthesized composite showed promising adsorption capacity for three dyes, following Freundlich adsorption isotherm and pseudo second order kinetics. Results from both column and batch adsorption experiments were in close agreement, demonstrating the potential of the synthesized composite for dye removal applications.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2021)
Article
Polymer Science
Mohammad T. T. ALSamman, Julio Sanchez
Summary: New biobased hydrogels were prepared for the adsorption of As(V) and Cu(II) using polyacrylamide/chitosan (PAAM/chitosan) hydrogel and polyacrylic acid/alginate (PAA/alginate) hydrogel, respectively. The characterization of hydrogels revealed the morphology, porosity, and surface charge modification caused by the addition of biopolymers. The adsorption results showed efficient removal of arsenic and copper ions, and the hydrogels can be regenerated for several cycles.
Article
Environmental Sciences
Flavia Melara, Thais Strieder Machado, Ingridy Alessandretti, Christian Manera, Daniele Perondi, Marcelo Godinho, Jeferson Steffanello Piccin
Summary: Chitosan/alginate composites were developed with the addition of activated carbon produced from tannery waste, showing enhanced adsorption performance in the removal of textile dye. The synergistic effect of activated carbon was observed, leading to a significant increase in the adsorption capacity of the composites. The composite material showed promising results in treating real textile effluent by reducing BOD, COD, turbidity, and color.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
(2021)
Article
Engineering, Chemical
Otavio A. Silva, Michelly G. Pella, Ketul C. Popat, Matt J. Kipper, Adley F. Rubira, Alessandro F. Martins, Heveline D. M. Follmann, Rafael Silva
Summary: This study presents a simple and effective method to prepare cell-compatible drug nanocarriers using human hair as a sustainable keratin source. The extracted rod-shaped keratin nanoparticles (KNPs) demonstrated improved properties compared to KNPs prepared using alkaline methods. They exhibited cytocompatibility towards adipose mesenchymal stem cells and healthy cells, and were found to be a suitable carrier for the anticancer drug berberine. The photothermal properties of the KNPs enhanced the drug release and cytotoxicity against colon adenocarcinoma cells.
ADVANCED POWDER TECHNOLOGY
(2022)
Review
Materials Science, Multidisciplinary
Zhenzhen Huang, Yanxin Wang, Linjun Huang, Bingyang Li, Xianhang Yan, Yao Wang, Matt J. Kipper, Jianguo Tang
Summary: Rare earth complexes are known for their unique luminescence characteristics and electrospinning techniques can be used to obtain fiber membranes with high fluorescence efficiency and stable mechanical properties. These fluorescent nanofibers have various applications in color-tunable materials and oxygen sensing materials.
JOURNAL OF MATERIALS SCIENCE
(2022)
Article
Chemistry, Applied
Elizangela H. Fragal, Vanessa H. Fragal, Elisangela P. Silva, Alexandre T. Paulino, Edson C. da Silva Filho, Marcos R. Mauricio, Rafael Silva, Adley F. Rubira, Edvani C. Muniz
Summary: This review presents recent advances in polysaccharide-based magnetic hydrogels as smart platforms for various biomedical applications, covering their synthesis methods, synergic properties, and contributions in drug delivery, tissue regeneration, and hyperthermia therapy.
CARBOHYDRATE POLYMERS
(2022)
Article
Chemistry, Physical
Manuel E. G. Winkler, Elisangela P. da Silva, Marcos H. Kunita, Adley F. Rubira
Summary: This study presents a method for obtaining silica particles through pressured carbonation and demonstrates the influence of CO2 pressure on material properties. The simplicity and practical importance of this method, as well as its ability to synthesize various types of silica materials and composites, are highlighted.
Article
Environmental Sciences
Mario Cezar Pozza Junior, Andressa Giombelli Rosenberger, Franciele Fernanda da Silva, Douglas Cardoso Dragunski, Edvani Curti Muniz, Josiane Caetano
Summary: The use of electrochemical sensors in the detection and quantification of chemical agents from environmental samples is effective for monitoring environmental quality. In this study, a polymer-based sensor for 2,4,6-trichlorophenol determination was developed using electrospinning of a blend of poly(lactic acid)/poly(butylene adipate-co-terephthalate) (PLA/PBAT) with graphite. The thermal treatment of graphite-containing fibres improved the adhesion surface for adsorption of the analyte, leading to enhanced peak current in the electrochemical tests. The developed PLA/PBAT/Graphite sensor exhibited excellent detection and quantification limits, as well as a strong linear response.
ENVIRONMENTAL TECHNOLOGY
(2023)
Review
Materials Science, Multidisciplinary
Xinhui Mao, Yanxin Wang, Xianhang Yan, Zhenzhen Huang, Zhiyuan Gao, Yuxuan Wang, Linjun Huang, Matt J. Kipper, Jianguo Tang
Summary: Human activities are generating increasing amounts of oily water, making oil/water separation methods crucial. Membranes and nanofibers with superwetting surfaces offer low cost, high efficiency, and environmental friendliness in oil/water separation. This review discusses various types of superwetting membranes, their structural features, manufacturing technology, applications, and outlines the challenges and future opportunities in the field of oil/water separation.
JOURNAL OF MATERIALS SCIENCE
(2023)
Article
Chemistry, Multidisciplinary
Michelly C. G. Pella, Andressa R. Simao, Marcos R. Mauricio, Douglas C. Dragunski, Rafael da Silva, Adley F. Rubira
Summary: This study evaluated the effects of different parameters on the properties of starch. The results showed that the volume and temperature of GMA had an impact on the DS and X-c, and their correlation increased the DS and Xc. Higher temperatures also favored hydrolysis. Although parameter correlations did not have a significant effect on the assessed properties, they changed the effect of individual parameters.
JOURNAL OF THE BRAZILIAN CHEMICAL SOCIETY
(2022)
Article
Materials Science, Multidisciplinary
Zhenzhen Huang, Yanxin Wang, Xianhang Yan, Xinhui Mao, Zhiyuan Gao, Matt J. Kipper, Linjun Huang, Jianguo Tang
Summary: In this study, a luminescent lanthanide complex, Eu(tta)3phen, was used to prepare fluorescent nanofiber films. The nanofibers, composed of chitosan and polyethylene oxide containing silica nanoparticles, encapsulated the Eu(tta)3phen. The resulting Na-CS/PEO-SiO2@Eu(tta)3phen fiber film showed high sensitivity and a wide detection range, making it a recyclable sensor for the detection of Cu2+ ions.
Article
Polymer Science
Alessandra Ruyz Medeiros, Fabiana da Silva Lima, Andressa Giombelli Rosenberger, Douglas Cardoso Dragunski, Edvani Curti Muniz, Eduardo Radovanovic, Josiane Caetano
Summary: This study aimed to use electrospinning to obtain PBAT/PLA polymer fibers with semiconductors TiO2-R and Fe3O4 to enhance the photocatalytic degradation of environmental contaminants. The parameters used in electrospinning were a needle to target distance of 12 cm, a flow rate of 1 mL h(-1), and a voltage of 14 kV. The best mass ratio of semiconductors in the fibers was determined to be 10% TiO2-R and 1% Fe3O4 at pH 7.0. Characterization techniques such as SEM, DSC, XRD, TGA, and FTIR confirmed the presence of TiO2-R and Fe3O4 in the fibers and their interaction with the polymers, leading to changes in crystallinity and degradation temperature. The fibers exhibited a 64.0% efficiency in degrading Reactive Red 195 dye within 24 hours, indicating potential for photocatalytic degradation of environmental contaminants.
Article
Biochemistry & Molecular Biology
Otavio A. Silva, Michelly G. Pella, Roberta M. Sabino, Ketul C. Popat, Matt J. Kipper, Adley F. Rubira, Heveline D. M. Follmann, Rafael Silva, Alessandro F. Martins
Summary: Carboxymethylcellulose (CMC) and keratin nanoparticle (KNP) hydrogels were obtained and characterized as drug delivery systems (DDSs) for the first time. The hydrogels were crosslinked with KNPs and the mechanical properties influenced the hydrogel stability and drug release. The hydrogels showed sustained release of the drug prednisolone (PRED) and exhibited cytocompatibility with mammalian cells. This study provides a straightforward procedure for creating chemically crosslinked DDSs using polysaccharides and proteins for efficient drug delivery.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Materials Science, Multidisciplinary
Kessily B. Rufato, Fernanda R. Veregue, Rodrigo de Paula Medeiro, Camila B. Francisco, Paulo R. Souza, Ketul C. Popat, Matt J. Kipper, Alessandro F. Martins
Summary: Poly(vinyl alcohol) (PVA) is a hydrophilic and cytocompatible polymer used in various fields, but its aqueous solubility limits its direct application. This study introduces PVA/Tanfloc (PVA/TN) electrospun fibers, which are chemically crosslinked to enhance stability. Different crosslinkers, such as glutaraldehyde (GA) and thermal treatment, were evaluated. The thermal treatment method was found to be the most effective in maintaining fiber morphology and promoting aqueous durability.
MATERIALS TODAY COMMUNICATIONS
(2023)
Article
Nanoscience & Nanotechnology
Xianhang Yan, Yanxin Wang, Zhenzhen Huang, Zhiyuan Gao, Xinhui Mao, Matt J. Kipper, Linjun Huang, Jianguo Tang
Summary: In this paper, Janus PAN nanofiber membranes (PNM) were prepared by co blending hydrophilic SiO2 nanoparticles, carbon nanotubes (CNTs) doped with PAN (PNM-SiO2 and PNM-CNT, respectively) and then using sequential multilayer electrospinning. The existence of electrostatic mutual gravitational force between SiO2 and CNTs makes the binding between the multilayer membranes exist more firmly. Janus PAN membranes have different wetting properties and can efficiently separate water-in-oil and oil-in-water emulsions with high flux and separation efficiency.
ACS APPLIED NANO MATERIALS
(2023)
Article
Engineering, Environmental
Elisangela Pacheco da Silva, Vanessa Hafemann Fragal, Elizangela Hafemann Fragal, Thiago Sequinel, Luiz Fernando Gorup, Rafael Silva, Edvani C. Muniz
Summary: Plastic waste consumption has been exponentially increasing every year, posing a significant environmental concern in modern society. Improper disposal of used supercapacitors also leads to serious environmental impacts. Transforming trash into high-valued materials, such as carbon nanomaterial supercapacitors, is a critical action to address these issues.
Article
Engineering, Biomedical
Somayeh Baghersad, Liszt Y. C. Madruga, Alessandro F. Martins, Ketul C. Popat, Matt J. Kipper
Summary: This study developed an antibacterial polyelectrolyte multilayer (PEM) coating containing a plant-derived condensed tannin polymer. The use of this polymer allowed stable PEM formation and exhibited remarkable antiadhesive and bactericidal properties against Pseudomonas aeruginosa and Staphylococcus aureus.
JOURNAL OF FUNCTIONAL BIOMATERIALS
(2023)
Article
Chemistry, Applied
Luiz B. S. Filho, Ronaldo C. Coelho, Edvani C. Muniz, Herbert de S. Barbosa
Summary: This study analyzed 209 articles on pectin extraction via response surface methodology (RSM) collected from Web of Science(C) and Scopus(C), using Bibliometrix for science mapping analysis. The trends in optimization and extraction methods of pectin via RSM were identified. The results showed that China was the most active country in terms of local productions, while Iran, Brazil, India, and the United Kingdom contributed to international collaborative publications. Assisted extraction methods and the physical and functional properties of pectin have gained more relevance in recent years.
CARBOHYDRATE POLYMER TECHNOLOGIES AND APPLICATIONS
(2022)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
