Article
Environmental Sciences
Wei Liu, Tao Lin, Xue Zhang, Fuchun Jiang, Xiaoshu Yan, Han Chen
Summary: In this study, we investigated the role of nanobubbles in the adsorption process of perfluoroalkyl acids (PFAAs) using a chitosan/granular activated carbon composite adsorbent. Our findings showed that nanobubbles can enhance the removal rate of PFAAs, and PFAAs with different chain lengths have different adsorption mechanisms. Longer chain PFAAs can be directly enriched on the composite adsorbents, while electrostatic interactions primarily affect the adsorption of shorter chain PFAAs.
Article
Engineering, Environmental
Shi-Cheng Liu, Ming-Bang Wu, Hao Ye, Lin Liu, Lu-Lin Ma, Juming Yao
Summary: The study introduces a method for uranium recovery from seawater using amidoximated cellulose as adsorbents, fabricated through two steps of homogeneous reactions. These adsorbents exhibit excellent properties in resisting marine pollutants and enhancing mass transfer performance.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Materials Science, Paper & Wood
Liangzhi Qiao, Shanshan Wang, Tao Wang, Shasha Yu, Shaohui Guo, Kaifeng Du
Summary: In this study, polyelectrolyte microspheres derived from chitosan and cellulose were successfully constructed for the efficient removal of dye contaminants from water. The microspheres showed high adsorption capacity, fast adsorption kinetics, and good reusability, indicating a great potential for dye removal applications.
Article
Chemistry, Applied
Di Wen, Zhen Dong, Yinyong Ao, Kangjun Xie, Maolin Zhai, Long Zhao
Summary: In this study, n-aminotriazole isomers modified cellulose microspheres were prepared as adsorbents for U(VI) via radiation technology. Batch adsorption experiments showed good adsorption capacity and selectivity of n-ATARs. Furthermore, 3-ATAR and 4-ATAR were found to be more suitable for extracting U(VI) from contaminated groundwater and simulated seawater, respectively.
CARBOHYDRATE POLYMERS
(2021)
Article
Chemistry, Physical
Yaqi Gong, Liming Liu, Fen Wang, Ying Pei, Shilin Liu, Renliang Lyu, Xiaogang Luo
Summary: Aminated chitosan/cellulose nanocomposite microspheres were successfully prepared for low concentration SMX removal, achieving high removal efficiency and analyzing the adsorption mechanism through kinetic and isothermal models. The stability and adsorption performance of ACNM were verified through cycling and column adsorption experiments.
JOURNAL OF MOLECULAR LIQUIDS
(2021)
Article
Materials Science, Paper & Wood
Zhiyong Zhang, Tang Liu, Deyi Wu
Summary: In this study, hydrous zirconia-impregnated chitosan beads (HZCB) with excellent stability and phosphate removal performance were synthesized. The dominant adsorption mechanism for phosphate was the direct coordination to Zr atoms by replacing hydroxyls. The adsorbed phosphate could be successfully eluted by an NaOH solution and the material could be repeatedly used.
Article
Engineering, Environmental
Baskaran Stephen Inbaraj, Kandi Sridhar, Bing-Huei Chen
Summary: This study successfully synthesized a magnetic activated carbon nanocomposite (MNPsGTAC) from green tea leaf waste and evaluated its adsorption efficiency for 4 priority polycyclic aromatic hydrocarbons (PAHs). The MNPsGTAC showed rapid kinetics, high removal rates, and good recyclability, with successful applications in various water environments for efficient PAH removal.
JOURNAL OF HAZARDOUS MATERIALS
(2021)
Article
Engineering, Environmental
Qiuyan Luo, Tingting Ren, Zihua Lei, Yifeng Huang, Yong Huang, Dong Xu, Caichao Wan, Xin Guo, Yiqiang Wu
Summary: In this study, a non-toxic chitosan-based hydrogel was developed with strong sorption and sensitive detection abilities for tetracycline. Cellulose nanocrystals improved the adsorption ability, while carbon dots served as fluorescent probes for detecting tetracycline with high selectivity and sensitivity.
CHEMICAL ENGINEERING JOURNAL
(2022)
Article
Biochemistry & Molecular Biology
Mehdi Barzegarzadeh, Mohammad Sadegh Amini-Fazl, Negin Sohrabi
Summary: This study synthesized chitosan-based hydrogel beads with different contents of iron oxide-graphene quantum dots for the ultrasonic-assisted removal of chlorpyrifos from wastewater. The results showed that the chitosan/graphene quantum dot-iron oxide (10) had the highest adsorption efficiency of 99.997%. Furthermore, the study demonstrated that the ultrasonic-assisted removal significantly reduced the equilibration time of chlorpyrifos.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Chemistry, Multidisciplinary
Mohamad Nasran Nasehir Khan, Mohamad Firdaus Mohamad Yusop, Muhamad Faizal Pakir Mohamed Latiff, Mohd Azmier Ahmad
Summary: This study investigated the adsorption of oxytetracycline (OXY) from aqueous solution using landscape biomass waste-based activated carbon (LBWAC) in both batch and continuous modes. The results showed that the adsorbent had the highest uptake at a solution temperature of 60 degrees C and a solution pH of 12. The adsorption system followed the Langmuir model and pseudo-second-order kinetics. The continuous bed column study demonstrated that the breakthrough point, exhaustion time, and maximum adsorption uptake can be improved by adjusting the inlet conditions. This research suggests that LBWAC has great potential for large-scale OXY wastewater treatment.
ARABIAN JOURNAL OF CHEMISTRY
(2023)
Article
Engineering, Multidisciplinary
Kaituo Wang, Sihao Chen, Ruoxiang Qiu, Yaseen Muhammad, Lin Shao, Xiang Li, Yuezhou Wei, Toyohisa Fujita
Summary: This study reports the rapid preparation of activated carbon modified phosphoric acid-activated geo-polymer microspheres for fast adsorptive separation of ReO4-. The results show that this method has the advantages of low cost, high efficiency, and fast solid-liquid separation, and can be applied to the removal of ReO4- from industrial wastewater.
COMPOSITES PART B-ENGINEERING
(2022)
Article
Biotechnology & Applied Microbiology
Xiaohui Tang, Yaoyao Huang, Qiang He, Yongjuan Wang, Huaili Zheng, Yadan Hu
Summary: A novel magnetic adsorbent, nitrilotriacetic acid-modified magnetic chitosan microspheres (NDMCMs), was prepared for the removal of tetracycline antibiotics (TC) from wastewater. The adsorption capacity of NDMCMs was significantly influenced by solution pH and ion strength, with a higher adsorption capacity compared to MCMs. The adsorption mechanism involved various chemical interactions and followed a spontaneous, endothermic, and orderly process.
ENVIRONMENTAL TECHNOLOGY & INNOVATION
(2021)
Article
Materials Science, Paper & Wood
Mehmet Emin Ergun
Summary: Chitosan foams with desirable properties, such as mechanical strength, heat insulation, and flame retardancy, were produced by oven drying. The foams were reinforced with cellulose, boric acid, and activated carbon, resulting in low density and good compression properties.
Article
Chemistry, Physical
Geetha Gopal, M. Joyce Nirmala, Amitava Mukherjee
Summary: Indiscriminate usage of antibiotic Ciprofloxacin (CIPRO) in water bodies is a serious environmental threat. A novel clay-nanosheet supported with Fe-Cu nanocomposite was developed for efficient CIPRO removal. The composite was immobilised in a biodegradable chitosan-coated Alginate-CMC matrix to form nanocomposite beads for easy usage in column reactors. The removal efficiency of this system was high and it showed significant reduction in the toxic effects of CIPRO on algae.
SURFACES AND INTERFACES
(2023)
Review
Green & Sustainable Science & Technology
Y. Fang, L. Liu, H. Xiang, Y. Wang, X. Sun
Summary: This review focuses on the methods and mechanisms of heavy metal removal in water purification using carbon microsphere materials. The preparation methods and functionalization methods of carbon microspheres are discussed, as well as their advantages and applications in removing heavy metals. However, there are still some problems and challenges in the practical application of carbon microspheres that need to be addressed in future research.
MATERIALS TODAY SUSTAINABILITY
(2022)
Article
Biophysics
Ruilin Zhang, Lei Liu, Wei Li, Xiaogang Luo, Fengshou Wu
Summary: In this work, iron-doped carbon dots (Fe-CDs) with peroxidase mimicking property were prepared and their application for the detection of hydrogen peroxide (H2O2) and glucose was explored. The Fe-CDs emitted intense blue luminescence and exhibited remarkable peroxidase mimicking property. A new optical dual-mode method for the detection of H2O2 and glucose was successfully established based on these properties.
COLLOIDS AND SURFACES B-BIOINTERFACES
(2023)
Article
Chemistry, Applied
Xiang Li, Yilan Zhao, Yuan Qiu, Xiaogang Luo, Genyan Liu, Qi Sun
Summary: Neutrophil elastase (NE) is an important serine protease that can serve as a biomarker for inflammatory-related diseases. Only a few red-emitting fluorescence probes with low enhancement have been reported for NE detection. In this study, a novel NE fluorescent probe BP-NE was developed using the red-emitting fluorophore BP, which exhibited high quantum yield. BP-NE showed improved detection of NE activity with low limit of detection, high signal-to-noise ratio, and high affinity compared to previous red-emitting NE fluorescent probes. It was also able to quantitatively analyze endogenous NE levels in different cell lines and zebrafish, making it promising for NE disease research in vitro and in vivo.
Article
Chemistry, Applied
Miao He, Xiaolong Chen, Jing Zhang, Jiawei Li, Dong Zhao, Yang Huang, Danqun Huo, Xiaogang Luo, Changjun Hou
Summary: Accurately identifying different liquors from the same brand is crucial for protecting consumer rights and the market economy. This study investigates the spectral properties of liquors using UV, NIR, and multi-way fluorescence spectroscopy, and combines them with chemometrics to distinguish the liquors. By constructing a four-way fluorescence spectrum data array and utilizing mid-level data fusion, the accuracy, sensitivity, and specificity of liquor identification are significantly improved.
Article
Chemistry, Applied
Yuanyuan Chen, Peng Zhao, Zhikun Hu, Yi Liang, Haiyan Han, Mei Yang, Xiaogang Luo, Changjun Hou, Danqun Huo
Summary: In this study, amino-functionalized multilayer titanium carbide (NH2-Ti3C2Tx) was developed and applied for electrochemical detection of Cd2+ and Pb2+. The NH2-Ti3C2Tx exhibited satisfactory electrochemical performances and demonstrated good practicality in the simultaneous determination of Cd2+ and Pb2+ in food samples.
Article
Chemistry, Multidisciplinary
Jiaying Zhao, Yanyi Long, Congjuan He, Huisi Yang, Shixian Zhao, Xiaogang Luo, Danqun Huo, Changjun Hou
Summary: Heavy metal ion (HMI) pollution poses a serious threat to human health and the ecosystem. This study establishes a novel sensing platform based on ZIF-67-derived cobalt/nitrogen-doped carbon (NC) composite polyhedrons linked with multiwalled carbon nanotubes (MWCNTs) for simultaneous monitoring of Cd2+ and Pb2+. The proposed sensing platform exhibits a wide linear range and low limits of detection, showing outstanding anti-interference performance in actual water samples.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Jinjin Zeng, Binyu Zhao, Xiaogang Luo, Fengshou Wu
Summary: In this study, carbon dots-functionalized Fe3O4 nanocomposites (CDs@Fe3O4) were successfully prepared using a facile and cost-effective method. The nanocomposites demonstrated enhanced affinity towards hydrogen peroxide (H2O2) and higher peroxidaselike activity compared to bare Fe3O4 nanoparticles. A colorimetric method was developed based on CDs@Fe3O4 for the detection of H2O2 and glucose in real samples, with limit of detection (LOD) calculated to be 1.53 μM and 2.2 μM respectively. This work provides a new strategy for constructing artificial nanozymes for colorimetric sensing of H2O2 and related molecules.
DIAMOND AND RELATED MATERIALS
(2023)
Article
Food Science & Technology
Chen Yu, Xiaogang Luo, Fengshou Wu, Juan Zhang
Summary: A covalent organic framework/reduced graphene oxide composite (COF/rGO) was prepared and applied for headspace solid-phase microextraction (HS-SPME) of polycyclic aromatic hydrocarbons (PAHs) prior to gas chromatography-flame ionization detection (GC-FID). The COF/rGO composite effectively prevented the stacking of graphene oxide nanosheets and exhibited enhanced extraction efficiency, with high enrichment factors. The developed HS-SPME/GC-FID method showed good performance in the analysis of PAHs in honey, with high recoveries and reliable reproducibility.
FOOD ANALYTICAL METHODS
(2023)
Article
Nanoscience & Nanotechnology
Xiaogang Luo, Dongli Xie, Jing Su, Jianchen Hu
Summary: This study evaluated the adverse effects and toxic mechanisms of multi-walled carbon nanotubes (MWCNTs) on human ocular cells. The results showed that MWCNTs could enter the cells and cause cell damage, leading to decreased cell viabilities. RNA sequencing analysis identified key genes associated with MWCNT exposure, particularly inflammation-related genes. Validation experiments confirmed the upregulation of these genes and their regulation by long non-coding RNAs. These findings provide promising biomarkers for monitoring MWCNT-induced eye disorders and targets for developing preventive and therapeutic strategies.
INTERNATIONAL JOURNAL OF NANOMEDICINE
(2023)
Article
Instruments & Instrumentation
Kaiqiang Yao, Zhuodai Li, Chang Zong, Heng Tian, Xujia Luo, Guorui Liu, Youxin Kang, Zhiqiang Fu, Jian Rong, Weixiong Zhang, Yuxi Wang, Junjie Zeng, Xiangsheng Tian, Jiqiu Hu, Xiaogang Luo, Chunxian Liu, Minghai Yu, Feng Wu, Jingjing Chen, Juntao Liu, Zhiyi Liu
Summary: This study proposes a novel and compact borehole muon detector with high sensitivity, which can record the angle of incident muons and achieve imaging of target objects. The detector design and performance are validated through Monte Carlo simulations and experimental research. The results indicate that the detector has good positional and angular resolutions and high efficiency in identifying objects with different densities.
NUCLEAR INSTRUMENTS & METHODS IN PHYSICS RESEARCH SECTION A-ACCELERATORS SPECTROMETERS DETECTORS AND ASSOCIATED EQUIPMENT
(2023)
Article
Nanoscience & Nanotechnology
Jiangbo Dong, Jilin Zheng, Jingzhou Hou, Peng Zhao, Yi Liang, Jincan Lei, Xiaogang Luo, Changjun Hou, Danqun Huo
Summary: This study developed an ultrasensitive enzyme-free ratiometric electrochemical sensing platform for in-situ determination of cell-secreted H2O2. The platform uses ferrocene (Fc) as an internal reference probe and nanoflower Au-Co-MOF as a detection probe. The detection platform showed a detection limit as low as 32 nM, with excellent selectivity, reproducibility, stability, and biocompatibility. It has great potential for in-situ determination of cell-secreted H2O2.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Applied
Jing Zhang, Jiaxi Deng, Jia Zheng, Yi Ma, Huibo Luo, Xiaogang Luo, Changjun Hou, Danqun Huo
Summary: An acid-sensitive carbon dot fluorescence sensing array was studied for differentiating distilled spirits. The electrostatic interactions between CDs and organic acids influenced the protonation and fluorescence properties of CDs, resulting in changes in triple fluorescence emission. The fluorescence sensor showed a regular linear variation under acidic conditions (3.0 < pH < 6.2). A comprehensive study was conducted on different acids (8 species), different concentrations (0.1 mM, 1 mM, 10 mM, 40 mM), mixed acids (formic acid and acetic acid), and the quantification capability for acetic acid (0.01-1 mM). The sensor array demonstrated excellent recognition ability for complex analytes. Using linear discriminant analysis (LDA), the fluorescence sensor array achieved 100% accuracy in identifying 16 types of Baijiu and 21 types of distilled liquors.
Article
Chemistry, Applied
Wenxia Tian, Xiaofang Liu, Jia Zheng, Yi Ma, Huibo Luo, Xiaogang Luo, Changjun Hou, Danqun Huo
Summary: A fluorescence sensor array based on PEI-terminated silver nanoparticles and lanthanide metal ions (PEI@Ag NPs@Ln) was constructed to quickly discriminate different segmented Baijiu, controlling its grade and indirectly affecting the quality of the finished Baijiu. With the assistance of pattern recognition, segmented Baijiu from three cellars were successfully discriminated. The whole process takes only 2 min, highlighting its fast, effective, and simple characteristics and potential practical application in the detection field.
Article
Energy & Fuels
Wenwen Miao, Junxiang Wang, Gexian Li, Shilin Liu, Xiaogang Luo
Summary: Commercial polymer separators in lithium-ion batteries (LIBs) often have low thermal stability and electrolyte wettability, reducing battery performance and safety. In this study, novel PVA/cellulose composite membranes (P-CMs) were prepared through noncovalent cross-linking, exhibiting superior thermal degradation and minimal dimension change. The phase-separated 3D-network porous structure of P-CMs enhances Li+ transport and the cross-linking structure improves electrolyte affinity and interfacial compatibility.
JOURNAL OF ENERGY STORAGE
(2023)
Article
Construction & Building Technology
Yin Cheng, Xiaoyuan Wang, Jianzhuang Chen, Hao Yu, Jun Shen, Xiaogang Luo, Jianguo Li
Summary: This study proposed a method of treating circulating fluidized bed (CFB) fly ash with bubble-mixed lightweight soil (BMLS). Artificial air bubbles in BMLS were used to control the expansibility of CFB fly ash mixed with cement. The impact of CFB fly ash on the pore structure of BMLS with CFB fly ash (BMLS-CF) was investigated. The sulfur compounds in CFB fly ash reacted with cement in BMLS-CF to form ettringite and gypsum, which adhered to pores of various sizes. The accommodation of expansive substances in BMLS-CF increased with the volume and number of bubbles, with the best effect observed at a CFB fly ash content of 50-66.7%.
JOURNAL OF BUILDING ENGINEERING
(2023)
Article
Materials Science, Multidisciplinary
Xiaogang Luo, Zhongna Yan, Hang Luo, Xuefan Zhou, Boyuan Li, Man Zhang, Dou Zhang
Summary: This study reports significantly improved piezoelectric properties and DC resistivity of CaBi2Nb2O9 ceramics through Na+ and Sm3+ co-doping. An optimum composition of Ca-0.95(Na, Sm)(0.025)Bi2Nb2O9 is obtained, which possesses a high Curie point, a high piezoelectric coefficient, and a low DC electrical resistivity at high temperatures. Furthermore, the piezoelectric coefficient maintains about 90% of the initial value after annealing at 900 degrees C for 2 h.
ADVANCED POWDER MATERIALS
(2023)
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)