Abnormal effector and regulatory T cell subsets in paediatric-onset multiple sclerosis

Production of IL-17 by MAIT Cells Is Increased in Multiple Sclerosis and Is Associated with IL-7 Receptor Expression

(2018) Anne Willing et al.   JOURNAL OF IMMUNOLOGY

Mucosal-Associated Invariant T Cells in Autoimmune Diseases

(2018) Asako Chiba et al.   Frontiers in Immunology

Memory B Cells Activate Brain-Homing, Autoreactive CD4+ T Cells in Multiple Sclerosis

(2018) Ivan Jelcic et al.   CELL

Ocrelizumab versus Interferon Beta-1a in Relapsing Multiple Sclerosis

(2017) Stephen L. Hauser et al.   NEW ENGLAND JOURNAL OF MEDICINE

Associations between the gut microbiota and host immune markers in pediatric multiple sclerosis and controls

(2016) Helen Tremlett et al.   BMC Neurology

Neuropathologic, phenotypic and functional analyses of Mucosal Associated Invariant T cells in Multiple Sclerosis

(2016) Marion Salou et al.   CLINICAL IMMUNOLOGY

Regulatory T-cells in autoimmune diseases: Challenges, controversies and—yet—unanswered questions

(2015) Charlotte R. Grant et al.   AUTOIMMUNITY REVIEWS

T-cell receptor repertoire of human peripheral CD161hiTRAV1-2+ MAIT cells revealed by next generation sequencing and single cell analysis

(2015) Kathrin Held et al.   HUMAN IMMUNOLOGY

Identification of phenotypically and functionally heterogeneous mouse mucosal-associated invariant T cells using MR1 tetramers

(2015) Azad Rahimpour et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Polyfunctional, Pathogenic CD161+Th17 Lineage Cells Are Resistant to Regulatory T Cell–Mediated Suppression in the Context of Autoimmunity

(2015) Sharee A. Basdeo et al.   JOURNAL OF IMMUNOLOGY

Th Cell Diversity in Experimental Autoimmune Encephalomyelitis and Multiple Sclerosis

(2015) Kevin S. Carbajal et al.   JOURNAL OF IMMUNOLOGY

TLR2 Stimulation Regulates the Balance between Regulatory T Cell and Th17 Function: A Novel Mechanism of Reduced Regulatory T Cell Function in Multiple Sclerosis

(2015) Mukanthu H. Nyirenda et al.   JOURNAL OF IMMUNOLOGY

Proinflammatory GM-CSF–producing B cells in multiple sclerosis and B cell depletion therapy

(2015) Rui Li et al.   Science Translational Medicine

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

(2015) Yonghao Cao et al.   Science Translational Medicine

CD8+MAIT cells infiltrate into the CNS and alterations in their blood frequencies correlate with IL-18 serum levels in multiple sclerosis

(2014) Anne Willing et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets

(2014) A Kurioka et al.   Mucosal Immunology

Non-myeloablative autologous haematopoietic stem cell transplantation expands regulatory cells and depletes IL-17 producing mucosal-associated invariant T cells in multiple sclerosis

(2013) Sofia V. Abrahamsson et al.   BRAIN

T-cell homeostasis in pediatric multiple sclerosis: Old cells in young patients

(2013) B. Balint et al.   NEUROLOGY

Kinetics of IL-6 Production Defines T Effector Cell Responsiveness to Regulatory T Cells in Multiple Sclerosis

(2013) Bettina Trinschek et al.   PLoS One

In Active Relapsing-Remitting Multiple Sclerosis, Effector T Cell Resistance to Adaptive Tregs Involves IL-6-Mediated Signaling

(2013) A. Schneider et al.   Science Translational Medicine

The plasticity of human Treg and Th17 cells and its role in autoimmunity

(2013) Markus Kleinewietfeld et al.   SEMINARS IN IMMUNOLOGY

Diminished Th17 (not Th1) responses underlie multiple sclerosis disease abrogation after hematopoietic stem cell transplantation

(2012) Peter J. Darlington et al.   ANNALS OF NEUROLOGY

Increased Th17 response to myelin peptides in pediatric MS

(2012) David Vargas-Lowy et al.   CLINICAL IMMUNOLOGY

B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells

(2012) Tom A. Barr et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CCR2+CCR5+ T Cells Produce Matrix Metalloproteinase-9 and Osteopontin in the Pathogenesis of Multiple Sclerosis

(2012) W. Sato et al.   JOURNAL OF IMMUNOLOGY

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

(2011) E. J. Wehrens et al.   BLOOD

CD161highCD8+T cells bear pathogenetic potential in multiple sclerosis

(2011) Viviana Annibali et al.   BRAIN

Mucosal-associated invariant T cells regulate Th1 response in multiple sclerosis

(2011) Yusei Miyazaki et al.   INTERNATIONAL IMMUNOLOGY

Stat3 Phosphorylation Mediates Resistance of Primary Human T Cells to Regulatory T Cell Suppression

(2011) W. A. Goodman et al.   JOURNAL OF IMMUNOLOGY

Clinical, environmental, and genetic determinants of multiple sclerosis in children with acute demyelination: a prospective national cohort study

(2011) Brenda Banwell et al.   LANCET NEUROLOGY

HLA-DRB1 confers increased risk of pediatric-onset MS in children with acquired demyelination

(2011) G. Disanto et al.   NEUROLOGY

Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells

(2010) M. Dusseaux et al.   BLOOD

Antimicrobial activity of mucosal-associated invariant T cells

(2010) Lionel Le Bourhis et al.   NATURE IMMUNOLOGY

Preferential recruitment of interferon-γ-expressing TH17 cells in multiple sclerosis

(2009) Hania Kebir et al.   ANNALS OF NEUROLOGY

Abnormal B-cell cytokine responses a trigger of T-cell-mediated disease in MS?

(2009) Amit Bar-Or et al.   ANNALS OF NEUROLOGY

Abnormal T-cell reactivities in childhood inflammatory demyelinating disease and type 1 diabetes

(2007) Brenda Banwell et al.   ANNALS OF NEUROLOGY

Compromised CD4+ CD25highregulatory T-cell function in patients with relapsing-remitting multiple sclerosis is correlated with a reduced frequency of FOXP3-positive cells and reduced FOXP3 expression at the single-cell level

(2007) Koen Venken et al.   IMMUNOLOGY