Single-cell approaches reveal novel cellular pathways for megakaryocyte and erythroid differentiation

Large-Scale Clonal Analysis Resolves Aging of the Mouse Hematopoietic Stem Cell Compartment

(2018) Ryo Yamamoto et al.   Cell Stem Cell

Single cell analysis of normal and leukemic hematopoiesis

(2018) Benjamin J. Povinelli et al.   MOLECULAR ASPECTS OF MEDICINE

Clonal analysis of lineage fate in native haematopoiesis

(2018) Alejo E. Rodriguez-Fraticelli et al.   NATURE

Hematopoietic Hierarchy – An Updated Roadmap

(2018) Yifan Zhang et al.   TRENDS IN CELL BIOLOGY

Single-Cell Multi-omics: An Engine for New Quantitative Models of Gene Regulation

(2018) Jonathan Packer et al.   TRENDS IN GENETICS

Perivascular Niche Cells Sense Thrombocytopenia and Activate Platelet-Biased Hscs in an IL-1 Dependent Manner

(2018) Tiago C. Luis et al.   EXPERIMENTAL HEMATOLOGY

RNA velocity of single cells

(2018) Gioele La Manno et al.   NATURE

Population snapshots predict early haematopoietic and erythroid hierarchies

(2018) Betsabeh Khoramian Tusi et al.   NATURE

Hierarchically related lineage-restricted fates of multipotent haematopoietic stem cells

(2018) Joana Carrelha et al.   NATURE

Dynamics of genetically engineered hematopoietic stem and progenitor cells after autologous transplantation in humans

(2018) Serena Scala et al.   NATURE MEDICINE

Myelo-lymphoid lineage restriction occurs in the human haematopoietic stem cell compartment before lymphoid-primed multipotent progenitors

(2018) Serena Belluschi et al.   Nature Communications

Human haematopoietic stem cell lineage commitment is a continuous process

(2017) Lars Velten et al.   NATURE CELL BIOLOGY

Reconstructing blood stem cell regulatory network models from single-cell molecular profiles

(2017) Fiona K. Hamey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single-Cell Multiomics: Multiple Measurements from Single Cells

(2017) Iain C. Macaulay et al.   TRENDS IN GENETICS

Single-cell RNA-sequencing uncovers transcriptional states and fate decisions in haematopoiesis

(2017) Emmanouil I. Athanasiadis et al.   Nature Communications

Massively parallel digital transcriptional profiling of single cells

(2017) Grace X. Y. Zheng et al.   Nature Communications

Adult human megakaryocyte-erythroid progenitors are in the CD34+CD38midfraction

(2016) Chad Sanada et al.   BLOOD

Loss ofEzh2synergizes withJAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis

(2016) Takafumi Shimizu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Distinct myeloid progenitor–differentiation pathways identified through single-cell RNA sequencing

(2016) Roy Drissen et al.   NATURE IMMUNOLOGY

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

(2016) Thomas Moreau et al.   Nature Communications

Single-cell RNA sequencing reveals molecular and functional platelet bias of aged haematopoietic stem cells

(2016) Amit Grover et al.   Nature Communications

Inflammation-Induced Emergency Megakaryopoiesis Driven by Hematopoietic Stem Cell-like Megakaryocyte Progenitors

(2015) Simon Haas et al.   Cell Stem Cell

Spatial reconstruction of single-cell gene expression data

(2015) Rahul Satija et al.   NATURE BIOTECHNOLOGY

Distinct routes of lineage development reshape the human blood hierarchy across ontogeny

(2015) F. Notta et al.   SCIENCE

Brief Report: Single-Cell Analysis Reveals Cell Division-Independent Emergence of Megakaryocytes From Phenotypic Hematopoietic Stem Cells

(2015) Aline Roch et al.   STEM CELLS

High c-Kit expression identifies hematopoietic stem cells with impaired self-renewal and megakaryocytic bias

(2014) Joseph Y. Shin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate

(2014) Amit Grover et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The dynamics and regulators of cell fate decisions are revealed by pseudotemporal ordering of single cells

(2014) Cole Trapnell et al.   NATURE BIOTECHNOLOGY

CD41 expression marks myeloid-biased adult hematopoietic stem cells and increases with age

(2013) C. Gekas et al.   BLOOD

Clonal Analysis Unveils Self-Renewing Lineage-Restricted Progenitors Generated Directly from Hematopoietic Stem Cells

(2013) Ryo Yamamoto et al.   CELL

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy

(2013) Alejandra Sanjuan-Pla et al.   NATURE

Lineage Tracing

(2012) Kai Kretzschmar et al.   CELL

Hematopoietic Stem Cell Subtypes Expand Differentially during Development and Display Distinct Lymphopoietic Programs

(2012) Claudia Benz et al.   Cell Stem Cell

Lineage Tracing of Pf4-Cre Marks Hematopoietic Stem Cells and Their Progeny

(2012) Simon D. J. Calaminus et al.   PLoS One

Mixed-phenotype acute leukemia: clinical and laboratory features and outcome in 100 patients defined according to the WHO 2008 classification

(2011) E. Matutes et al.   BLOOD

Distinct Clinical Phenotypes Associated with JAK2V617F Reflect Differential STAT1 Signaling

(2010) Edwin Chen et al.   CANCER CELL

Prospective isolation and molecular characterization of hematopoietic stem cells with durable self-renewal potential

(2009) D. G. Kent et al.   BLOOD

Developmental biology: Instructions writ in blood

(2009) Tariq Enver et al.   NATURE

mRNA-Seq whole-transcriptome analysis of a single cell

(2009) Fuchou Tang et al.   NATURE METHODS