1,25‐Dihydroxyvitamin D exerts an antiaging role by activation of Nrf2‐antioxidant signaling and inactivation of p16/p53‐senescence signaling

Downregulation of cytoplasmic DNases is implicated in cytoplasmic DNA accumulation and SASP in senescent cells

(2018) Akiko Takahashi et al.   Nature Communications

Regulation of Cellular Senescence by Polycomb Chromatin Modifiers through Distinct DNA Damage- and Histone Methylation-Dependent Pathways

(2018) Takahiro Ito et al.   Cell Reports

The role of vitamin D in the endocrinology controlling calcium homeostasis

(2017) James C. Fleet   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Repression of the Antioxidant NRF2 Pathway in Premature Aging

(2016) Nard Kubben et al.   CELL

Naturally occurring p16Ink4a-positive cells shorten healthy lifespan

(2016) Darren J. Baker et al.   NATURE

Correction: Vitamin D and Risk of Multiple Sclerosis: A Mendelian Randomization Study

(2016) Lauren E. Mokry et al.   PLOS MEDICINE

Attenuation of constitutive DNA damage signaling by 1,25-dihydroxyvitamin D3

(2016) H. Dorota Halicka et al.   Aging-US

Overexpression of Bmi1 in Lymphocytes Stimulates Skeletogenesis by Improving the Osteogenic Microenvironment

(2016) Xichao Zhou et al.   Scientific Reports

Vitamin D cell signalling in health and disease

(2015) Michael J. Berridge   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Vitamin D: a custodian of cell signalling stability in health and disease

(2015) Michael J. Berridge   BIOCHEMICAL SOCIETY TRANSACTIONS

Deficiency of the parathyroid hormone-related peptide nuclear localization and carboxyl terminal sequences leads to premature skin ageing partially mediated by the upregulation of p27

(2015) Minyue Jiang et al.   EXPERIMENTAL DERMATOLOGY

Oxidative stress response and Nrf2 signaling in aging

(2015) Hongqiao Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Nrf2 regulatory network provides an interface between redox and intermediary metabolism

(2014) John D. Hayes et al.   TRENDS IN BIOCHEMICAL SCIENCES

Senescence and aging: the critical roles of p53

(2013) A Rufini et al.   ONCOGENE

Nrf2 knockout enhances intestinal tumorigenesis inApcmin/+mice due to attenuation of anti-oxidative stress pathway while potentiates inflammation

(2012) Ka Lung Cheung et al.   MOLECULAR CARCINOGENESIS

Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders

(2011) Darren J. Baker et al.   NATURE

p38 MAPK-Mediated Bmi-1 Down-Regulation and Defective Proliferation in ATM-Deficient Neural Stem Cells Can Be Restored by Akt Activation

(2011) Jeesun Kim et al.   PLoS One

An Improved Transplantation Strategy for Mouse Mesenchymal Stem Cells in an Acute Myocardial Infarction Model

(2011) Jianliang Jin et al.   PLoS One

The nuclear vitamin D receptor controls the expression of genes encoding factors which feed the “Fountain of Youth” to mediate healthful aging

(2010) Mark R. Haussler et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Vitamin D deficiency and mortality

(2009) Armin Zittermann et al.   CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE

Premature aging in vitamin D receptor mutant mice

(2009) Tiina Keisala et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Bmi1 regulates mitochondrial function and the DNA damage response pathway

(2009) Jie Liu et al.   NATURE

Continuous elimination of oxidized nucleotides is necessary to prevent rapid onset of cellular senescence

(2009) P. Rai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protective role of 1α, 25-dihydroxyvitamin D3 against oxidative stress in nonmalignant human prostate epithelial cells

(2008) Bo-Ying Bao et al.   INTERNATIONAL JOURNAL OF CANCER

Severe growth retardation and early lethality in mice lacking the nuclear localization sequence and C-terminus of PTH-related protein

(2008) D. Miao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA