Rapid and Long-Term Glycemic Regulation with a Balanced Charged Immune-Evasive Hydrogel in T1DM Mice

Novel Balanced Charged Alginate/PEI Polyelectrolyte Hydrogel that Resists Foreign-Body Reaction

(2018) Jiamin Zhang et al.   ACS Applied Materials & Interfaces

Cardiovascular Disease and Risk Management: Review of the American Diabetes Association Standards of Medical Care in Diabetes 2018

(2018) James J. Chamberlain et al.   ANNALS OF INTERNAL MEDICINE

Local immunomodulation with Fas ligand-engineered biomaterials achieves allogeneic islet graft acceptance

(2018) Devon M. Headen et al.   NATURE MATERIALS

Islet Encapsulation

(2018) Alexander Ulrich Ernst et al.   Journal of Materials Chemistry B

Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques

(2018) Matthew A. Bochenek et al.   Nature Biomedical Engineering

Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes

(2017) Duo An et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vasculogenic hydrogel enhances islet survival, engraftment, and function in leading extrahepatic sites

(2017) Jessica D. Weaver et al.   Science Advances

Microneedles Integrated with Pancreatic Cells and Synthetic Glucose-Signal Amplifiers for Smart Insulin Delivery

(2016) Yanqi Ye et al.   ADVANCED MATERIALS

From Micro to Macro: The Hierarchical Design in a Micropatterned Scaffold for Cell Assembling and Transplantation

(2016) Kai Wang et al.   ADVANCED MATERIALS

Transforming growth factor-beta 1 delivery from microporous scaffolds decreases inflammation post-implant and enhances function of transplanted islets

(2016) Jeffrey M.H. Liu et al.   BIOMATERIALS

Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

(2016) Arturo J Vegas et al.   NATURE BIOTECHNOLOGY

Approaching a cure for type 1 diabetes

(2016) Qizhi Tang et al.   NATURE MEDICINE

Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice

(2016) Arturo J Vegas et al.   NATURE MEDICINE

Advances in islet encapsulation technologies

(2016) Tejal Desai et al.   NATURE REVIEWS DRUG DISCOVERY

Versatile click alginate hydrogels crosslinked via tetrazine–norbornene chemistry

(2015) Rajiv M. Desai et al.   BIOMATERIALS

Biomaterial based modulation of macrophage polarization: a review and suggested design principles

(2015) Rukmani Sridharan et al.   Materials Today

A prevascularized subcutaneous device-less site for islet and cellular transplantation

(2015) Andrew R Pepper et al.   NATURE BIOTECHNOLOGY

Size- and shape-dependent foreign body immune response to materials implanted in rodents and non-human primates

(2015) Omid Veiseh et al.   NATURE MATERIALS

Novel immunological strategies for islet transplantation

(2015) Sara Tezza et al.   PHARMACOLOGICAL RESEARCH

Cell encapsulation via microtechnologies

(2014) AhRan Kang et al.   BIOMATERIALS

Long-Term Function of Islets Encapsulated in a Redesigned Alginate Microcapsule Construct in Omentum Pouches of Immune-Competent Diabetic Rats

(2014) Rajesh Pareta et al.   PANCREAS

Maintaining functional islets through encapsulation in an injectable saccharide–peptide hydrogel

(2013) Sophia W. Liao et al.   BIOMATERIALS

Zwitterionic hydrogels implanted in mice resist the foreign-body reaction

(2013) Lei Zhang et al.   NATURE BIOTECHNOLOGY

Angiogenic and osteogenic potential of platelet-rich plasma and adipose-derived stem cell laden alginate microspheres

(2012) Yi Man et al.   BIOMATERIALS

Transforming growth factor β-induced peritoneal fibrosis is mouse strain dependent*

(2012) Peter J. Margetts et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

In situ formation and collagen-alginate composite encapsulation of pancreatic islet spheroids

(2011) Bo Ram Lee et al.   BIOMATERIALS

Alginates as a useful natural polymer for microencapsulation and therapeutic applications

(2011) Cheong Hian Goh et al.   CARBOHYDRATE POLYMERS

Alginate: Properties and biomedical applications

(2011) Kuen Yong Lee et al.   PROGRESS IN POLYMER SCIENCE

Proangiogenic scaffolds as functional templates for cardiac tissue engineering

(2010) L. R. Madden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct effect of alginate purification on the survival of islets immobilized in alginate-based microcapsules

(2009) Geneviève Langlois et al.   Acta Biomaterialia

Ultralow-Fouling, Functionalizable, and Hydrolyzable Zwitterionic Materials and Their Derivatives for Biological Applications

(2009) Shaoyi Jiang et al.   ADVANCED MATERIALS

Global estimates of the prevalence of diabetes for 2010 and 2030

(2009) J.E. Shaw et al.   DIABETES RESEARCH AND CLINICAL PRACTICE

Optimal implantation site for pancreatic islet transplantation

(2008) S. Merani et al.   BRITISH JOURNAL OF SURGERY

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

An New Avenue to Nonfouling Materials

(2007) S. Chen et al.   ADVANCED MATERIALS