Article
Microbiology
Narda Medina, Ana Alastruey-Izquierdo, Oscar Bonilla, Osmar Gamboa, Danicela Mercado, Juan C. Perez, Luis Roberto Salazar, Eduardo Arathoon, David W. Denning, Juan Luis Rodriguez-Tudela
Summary: Opportunistic infections (OIs) and advanced HIV disease (AHD) are major contributors to HIV-related mortality in Guatemala. The incidence of OIs in newly diagnosed HIV patients was 21%, with histoplasmosis being the most common. Patients with OIs had a significantly higher mortality rate, but a program in Guatemala successfully reduced OI mortality and increased OI treatment rates.
Article
Gastroenterology & Hepatology
Tullio Prestileoa, Vito Di Marco, Ornella Dino, Adriana Sanfilippo, Marco Tutone, Maurizio Milesi, Lorenza Di Marco, Camila A. Picchio, Antonio Craxi, Jeffrey V. Lazarus
Summary: This study demonstrates the effectiveness and feasibility of infectious disease screening programs for migrants. The results show that migrants from Africa are vulnerable to infection with hepatitis B virus, hepatitis C virus, and human immunodeficiency virus during their journey. Women, individuals who stayed in Libya for a long time, and those who experienced physical and/or sexual violence are more susceptible to viral infections.
DIGESTIVE AND LIVER DISEASE
(2022)
Article
Chemistry, Analytical
Derrick Lau, James C. Walsh, Claire F. Dickson, Andrew Tuckwell, Jeffrey H. Stear, Dominic J. B. Hunter, Akshay Bhumkar, Vaibhav Shah, Stuart G. Turville, Emma Sierecki, Yann Gambin, Till Bocking, David A. Jacques
Summary: The study developed a fluorescence analysis method using HIV capsid as bait to screen for fluorescence-labeled binding molecules. By using a scanning stage, rapid detection was achieved without compromising sensitivity, providing a new approach for screening potential interactors.
ANALYTICAL CHEMISTRY
(2021)
Article
Immunology
David M. Higgins, MaShawn Moore, Lucy Alderton, Laura Weinberg, Andrew M. Hickok, Andrew Yale, Karen A. Wendel
Summary: This study evaluated the first year of an online, at-home program in Colorado called Test Yourself Colorado (TYC), which provides free mailed HIV tests and/or gonorrhea and chlamydia tests. The study found that TYC is a scalable tool that reaches at-risk populations and helps guide those with positive tests to treatment. However, HIV/STI home testing programs need to assess and address disparities by race and ethnicity to ensure equitable benefits for all communities at risk.
CLINICAL INFECTIOUS DISEASES
(2023)
Article
Public, Environmental & Occupational Health
John Harmon, Mary Michael Garver Kelley, Sonya L. Heath, Kelly L. Ross-Davis, Lauren A. Walter
Summary: Through studying HIV seroconverters in the emergency department, it was revealed that certain populations are disproportionately affected by race, history of intravenous drug use, mental health comorbidities, and lack of social factors. The findings suggest that the emergency department could provide a unique opportunity for intervention before HIV exposure, particularly for vulnerable populations.
AIDS PATIENT CARE AND STDS
(2021)
Article
Multidisciplinary Sciences
Kiran A. Faryar, Rachel M. Ancona, Zachary Reau, Sheryl B. Lyss, Robert S. Braun, Todd Rademaker, Ryane K. Sickles, Michael S. Lyons
Summary: During 2014-2018, the annual number of HIV diagnoses made by the ED program increased from 20 to 42 overall, with the ED contributing 18% of HIV diagnoses in the county and 22% of diagnoses among PWID. The study highlights the importance of ED HIV screening programs in identifying undiagnosed HIV infections among PWID during an HIV outbreak.
Article
Endocrinology & Metabolism
Fateme Kianpour, Mohammad Fararouei, Jafar Hassanzadeh, Mohammadnabi Mohammadi, Mostafa Dianatinasab
Summary: The study evaluated the performance of two commonly used diabetes screening tests, finding that the sensitivity of capillary fasting blood glucose (CBG) and glycated hemoglobin (HbA1c) were 69.01% and 84.5%, respectively. The new cut points for CBG and HbA1c were determined to be 116.5 mg/dl and 7.15%, respectively, leading to improved sensitivity and specificity.
DIABETOLOGY & METABOLIC SYNDROME
(2021)
Article
Health Care Sciences & Services
Jakub Furmaga, Samuel A. McDonald
Summary: The study evaluated the impact of Rapid Medical Evaluation (RME) on patient flow in the Emergency Department (ED) and found that implementing RME helped reduce the time patients spend in the ED Treatment Room, improved patient throughput, and decreased Door-to-Provider time during busy periods in the ED.
JOURNAL OF MEDICAL SYSTEMS
(2021)
Article
Psychology, Developmental
Jaron Smith, Paul Broker, Melony Chakrabarty, Jason Santiago, Jennifer Farabaugh, Janice Piatt, Kristen Samaddar
Summary: By educating and reminding the multidisciplinary team, creating a standardized workflow, introducing rapid HIV antibody testing, and implementing protocols, the rate of routine HIV screening during preventative visits for adolescents aged 15 to 21 was successfully increased. After four improvement cycles, the screening rate increased from 5.16% to 41.5%.
JOURNAL OF ADOLESCENT HEALTH
(2021)
Article
Chemistry, Multidisciplinary
Jinghang Xie, Ran Mu, Mingxi Fang, Yunfeng Cheng, Fiona Senchyna, Angel Moreno, Niaz Banaei, Jianghong Rao
Summary: This study presents a rapid screening assay for pathogenic bacteria resistant to lactam antibiotics, utilizing a fluorogenic probe that shows superior sensitivity in reporting the activity of beta-lactamases and allows for detection of resistant bacteria in urine samples within 2 hours.
Article
Multidisciplinary Sciences
Gheyath K. Nasrallah, Raniya Al-Buainain, Nadin Younes, Soha R. Dargham, Duaa W. Al-Sadeq, Mohamed Elhassan, Ibrahim Al-Shaar, Hadi M. Yassine, Laith J. Abu-Raddad, Mohamed M. Emara, Ahmed Ismail
Summary: HIV and Syphilis are common STIs that pose a concern and burden on healthcare systems. This study evaluated the diagnostic efficiency of the protocols used by the Medical Commission Department (MC) in Qatar for screening these infections.
Article
Medicine, General & Internal
John Crowe, Andy T. Schnaubelt, Scott SchmidtBonne, Kathleen Angell, Julia Bai, Teresa Eske, Molly Nicklin, Catherine Pratt, Bailey White, Brodie Crotts-Hannibal, Nicholas Staffend, Vicki Herrera, Jeramie Cobb, Jennifer Conner, Julie Carstens, Jonell Tempero, Lori Bouda, Matthew Ray, James Lawler, W. Scott Campbell, John-Martin Lowe, Joshua Santarpia, Shannon Bartelt-Hunt, Michael Wiley, David Brett-Major, Cheryl Logan, M. Jana Broadhurst
Summary: A pilot program in Omaha, Nebraska, tested staff and students in 3 urban public schools for SARS-CoV-2 over a 5-week period, detecting a higher infection rate compared to county-level data. Different experiences were observed among schools, and virus sequencing and geographical analyses indicated a dynamic relationship between school-based and community-derived transmission risks. These findings offer insights into the effectiveness and community value of test-based SARS-CoV-2 screening and surveillance strategies in kindergarten through 12th grade educational settings.
Article
Microbiology
Hilal Al Sidairi, Emma K. Reid, Jason J. LeBlanc, Navjot Sandila, Joline Head, Ian Davis, Paul Bonnar
Summary: This study evaluated the impact of rapid molecular testing for MSSA and MRSA coupled with an antimicrobial stewardship program (ASP) intervention. The results showed that molecular testing significantly reduced the time to MSSA and MRSA discrimination and that the ASP intervention could reduce the time to optimal therapy. This study is important for improving treatment outcomes in patients with serious bloodstream infections.
MICROBIOLOGY SPECTRUM
(2023)
Article
Virology
Majdouline El Moussaoui, Nathalie Maes, Samuel L. Hong, Nicolas Lambert, Stephanie Gofflot, Patricia Dellot, Yasmine Belhadj, Pascale Huynen, Marie-Pierre Hayette, Cecile Meex, Sebastien Bontems, Justine Defeche, Lode Godderis, Geert Molenberghs, Christelle Meuris, Maria Artesi, Keith Durkin, Souad Rahmouni, Celine Gregoire, Yves Beguin, Michel Moutschen, Simon Dellicour, Gilles Darcis
Summary: Healthcare workers, especially nurses, paramedics, and laboratory staff handling respiratory samples, are at higher risk of SARS-CoV-2 infections. Phylogenetic analysis reveals that most positive samples were independently introduced into the hospital.
Article
Pharmacology & Pharmacy
Brandon Ho, Chau-Minh Phan, Piyush Garg, Parvin Shokrollahi, Lyndon Jones
Summary: This study developed an innovative screening platform using a millifluidic device and automated image analysis to accurately measure the degradation of biodegradable hydrogels and the subsequent release of entrapped compounds. The results proved the feasibility of this visual method and supported its use for evaluating hydrogel degradation and the release of therapeutic compounds.
Letter
Immunology
Amir M. Mohareb, Anuj V. Patel, Oliver B. Laeyendecker, Matthew F. Toerper, Danielle Signer, William A. Clarke, Gabor D. Kelen, Thomas C. Quinn, Jason S. Haukoos, Richard E. Rothman, Yu-Hsiang Hsieh
JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES
(2021)
Article
Microbiology
Steven E. Conklin, Kathryn Martin, Yukari C. Manabe, Haley A. Schmidt, Jernelle Miller, Morgan Keruly, Ethan Klock, Charles S. Kirby, Owen R. Baker, Reinaldo E. Fernandez, Yolanda J. Eby, Justin Hardick, Kathryn Shaw-Saliba, Richard E. Rothman, Patrizio P. Caturegli, Andrew D. Redd, Aaron A. R. Tobian, Evan M. Bloch, H. Benjamin Larman, Thomas C. Quinn, William Clarke, Oliver Laeyendecker
Summary: This study compared the performance of 15 different lateral flow POCTs for detecting SARS-CoV-2-specific antibodies and found variations in sensitivity and specificity. Additionally, the study observed differences in the timing of appearance of IgM and IgG bands.
JOURNAL OF CLINICAL MICROBIOLOGY
(2021)
Article
Immunology
M. Kate Grabowski, Eshan U. Patel, Gertrude Nakigozi, Victor Ssempijja, Robert Ssekubugu, Joseph Ssekasanvu, Anthony Ndyanabo, Godfrey Kigozi, Fred Nalugoda, Ronald H. Gray, Sarah Kalibbala, David M. Serwadda, Oliver Laeyendecker, Maria J. Wawer, Larry W. Chang, Thomas C. Quinn, Joseph Kagaayi, Aaron A. R. Tobian, Steven J. Reynolds
Summary: Limited data on individual HIV viral load trajectories at the population-level after the introduction of universal test and treat (UTT) in sub-Saharan Africa. The proportion of durable viral load suppression increased during UTT rollout, but a substantial portion of the population with younger, male, and mobile characteristics remained persistently viremic.
JOURNAL OF INFECTIOUS DISEASES
(2021)
Article
Biology
Doug Morrison, Oliver Laeyendecker, Ron Brookmeyer
Summary: The study introduces a method for generalized linear regression with interval-censored covariates, which indirectly infers the distribution of the covariate of interest compared to other conventional approaches. The proposed method shows less bias but slight increases in standard error when compared to midpoint analysis and uniform imputation methods.
Article
Immunology
Bezawit A. Woldemeskel, Andrew H. Karaba, Caroline C. Garliss, Evan J. Beck, Kristy H. Wang, Oliver Laeyendecker, Andrea L. Cox, Joel N. Blankson
Summary: Past studies have shown that some vaccines do not elicit optimal responses in individuals living with HIV. However, this study demonstrates that the BNT162b2 vaccine induces robust immune responses in these patients comparable to those in healthy donors.
CLINICAL INFECTIOUS DISEASES
(2022)
Article
Substance Abuse
Eshan U. Patel, Sunil S. Solomon, Gregory M. Lucas, Allison M. McFall, Cecilia Tomori, Aylur K. Srikrishnan, Muniratnam S. Kumar, Oliver Laeyendecker, David D. Celentano, David L. Thomas, Thomas C. Quinn, Shruti H. Mehta
Summary: This study assessed the association between drug use stigma and active HCV infection among people who inject drugs in India. Results showed that drug use stigma plays a role in HCV transmission and is significantly associated with injection drug use-related risk behaviors.
INTERNATIONAL JOURNAL OF DRUG POLICY
(2021)
Article
Emergency Medicine
Oliver Laeyendecker, Yu-Hsiang Hsieh, Richard E. Rothman, Gaby Dashler, Thomas Kickler, Reinaldo E. Fernandez, William Clarke, Eshan U. Patel, Aaron A. R. Tobian, Gabor D. Kelen, Thomas C. Quinn
Summary: The study found that the burden of COVID-19 in Baltimore City increased significantly during the early stages of the pandemic, with a higher prevalence among Hispanic individuals. Independent factors associated with acute infection included Hispanic ethnicity, loss of smell or taste, subjective fever, cough, muscle ache and fever, while factors associated with convalescent infection included Hispanic ethnicity and low oxygen saturation.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2021)
Article
Infectious Diseases
Charles Ssuuna, Ronald Moses Galiwango, Edward Nelson Kankaka, Joseph Kagaayi, Anthony Ndyanabo, Godfrey Kigozi, Gertrude Nakigozi, Tom Lutalo, Robert Ssekubugu, John Bosco Wasswa, Anthony Mayinja, Martina Cathy Nakibuuka, Samiri Jamiru, John Baptist Oketch, Edward Muwanga, Larry William Chang, Mary Kate Grabowski, Maria Wawer, Ronald Gray, Mark Anderson, Michael Stec, Gavin Cloherty, Oliver Laeyendecker, Steven James Reynolds, Thomas C. Quinn, David Serwadda
Summary: The study found a high seroprevalence of antibodies to SARS-CoV-2 among HCW in South-Central Uganda, with a rate of 26.7%. Additionally, individuals presenting with specific COVID-19 like symptoms had a seroprevalence rate of 15.6%. Prior to the first confirmed COVID-19 case in Uganda, 2.3% of collected plasma specimens exhibited reactivity.
BMC INFECTIOUS DISEASES
(2022)
Article
Microbiology
Evan J. Beck, Yu-Hsiang Hsieh, Reinaldo E. Fernandez, Gaby Dashler, Emily R. Egbert, Shawn A. Truelove, Caroline Garliss, Richard Wang, Evan M. Bloch, Ruchee Shrestha, Joel Blankson, Andrea L. Cox, Yukari C. Manabe, Thomas Kickler, Richard E. Rothman, Andrew D. Redd, Aaron A. R. Tobian, Aaron M. Milstone, Thomas C. Quinn, Oliver Laeyendecker
Summary: Emergency departments can be used as surveillance sites for infectious diseases. This study aimed to determine the burden of SARS-CoV-2 infection and monitor the prevalence of COVID-19 vaccination among patients attending an urban ED in Baltimore City. A testing algorithm was developed to differentiate between previously infected, vaccinated, and unexposed individuals using antibody assays. The study found significant differences in disease burden and vaccination coverage based on sex, race, and ethnicity.
JOURNAL OF CLINICAL MICROBIOLOGY
(2022)
Article
Multidisciplinary Sciences
Chris Wymant, Daniela Bezemer, Francois Blanquart, Luca Ferretti, Astrid Gall, Matthew Hall, Tanya Golubchik, Margreet Bakker, Swee Hoe Ong, Lele Zhao, David Bonsall, Mariateresa de Cesare, George MacIntyre-Cockett, Lucie Abeler-Doerner, Jan Albert, Norbert Bannert, Jacques Fellay, M. Kate Grabowski, Barbara Gunsenheimer-Bartmeyer, Huldrych F. Gunthard, Pia Kivela, Roger D. Kouyos, Oliver Laeyendecker, Laurence Meyer, Kholoud Porter, Matti Ristola, Ard van Sighem, Ben Berkhout, Paul Kellam, Marion Cornelissen, Peter Reiss, Christophe Fraser
Summary: A highly virulent variant of subtype-B HIV-1 was discovered in the Netherlands. Infected individuals with this variant had significantly higher viral loads and faster decline in CD4 cells compared to other subtype-B strains. The increased virulence is attributed to the viral strain, and the variant emerged in the 1990s with increased transmissibility and an unfamiliar molecular mechanism of virulence.
Article
Medicine, Research & Experimental
Han-Sol Park, Janna R. Shapiro, Ioannis Sitaras, Bezawit A. Woldemeskel, Caroline C. Garliss, Amanda Dziedzic, Jaiprasath Sachithanandham, Anne E. Jedlicka, Christopher A. Caputo, Kimberly E. Rousseau, Manjusha Thakar, San Suwanmanee, Pricila Hauk, Lateef Aliyu, Natalia Majewska, Sushmita Koley, Bela Patel, Patrick Broderick, Giselle Mosnaim, Sonya L. Heath, Emily S. Spivak, Aarthi Shenoy, Evan M. Bloch, Thomas J. Gniadek, Shmuel Shoham, Arturo Casadevall, Daniel Hanley, Andrea L. Cox, Oliver Laeyendecker, Michael J. Betenbaugh, Steven M. Cramer, Heba H. Mostafa, Andrew Pekosz, Joel N. Blankson, Sabra L. Klein, Aaron A. R. Tobian, David Sullivan, Kelly A. Gebo
Summary: Benchmarks for protective immunity from infection or severe disease after SARS-CoV-2 vaccination are still being defined. In this study, the researchers compared different immune responses and viral variants in different groups, including vaccinated individuals and symptomatic patients. The findings showed that neutralizing antibody levels declined over time and were lower against the Alpha variant. Partially and fully vaccinated patients had lower neutralizing antibody levels against the parent virus compared to healthy controls. The study also found that neutralization activity against the Alpha variant was lower in the partially and fully vaccinated infected patients. Parent virus neutralization was identified as a predictive factor for breakthrough infections with the Alpha variant.
Article
Microbiology
Andrew D. Redd, Alessandra Nardin, Hassen Kared, Evan M. Bloch, Brian Abel, Andrew Pekosz, Oliver Laeyendecker, Michael Fehlings, Thomas C. Quinn, Aaron A. R. Tobian
Summary: This study found that the newly identified Omicron variant of concern contains only one mutation in a low-prevalence epitope targeted by CD8(+) T cells, suggesting that the T-cell immune response in previously infected and vaccinated individuals should still be effective against Omicron.
Article
Microbiology
Andrew H. Karaba, Trevor S. Johnston, Evan Beck, Oliver Laeyendecker, Andrea L. Cox, Sabra L. Klein, David J. Sullivan
Summary: The relevance of preexisting immunity to the four endemic human coronaviruses in the first week of COVID-19 illness on the outcome of COVID-19 progression stems from the high prevalence of the ehCoV and SARS-CoV-2 coronaviruses. The question has been raised of whether therapeutic convalescent plasma or control plasma containing ehCoV antibodies might alter the outcome of COVID-19 progression to hospitalization.
Editorial Material
Emergency Medicine
Gabor D. Kelen
ANNALS OF EMERGENCY MEDICINE
(2023)
Article
Microbiology
Feben Habtehyimer, Xianming Zhu, Andrew D. Redd, Kelly A. Gebo, Alison G. Abraham, Eshan U. Patel, Oliver Laeyendecker, Thomas J. Gniadek, Reinaldo E. Fernandez, Owen R. Baker, Malathi Ram, Edward R. Cachay, Judith S. Currier, Yuriko Fukuta, Jonathan M. Gerber, Sonya L. Heath, Barry Meisenberg, Moises A. Huaman, Adam C. Levine, Aarthi Shenoy, Shweta Anjan, Janis E. Blair, Daniel Cruser, Donald N. Forthal, Laura L. Hammitt, Seble Kassaye, Giselle S. Mosnaim, Bela Patel, James H. Paxton, Jay S. Raval, Catherine G. Sutcliffe, Matthew Abinante, Kevin S. Oei, Valerie Cluzet, Marie Elena Cordisco, Benjamin Greenblatt, William Rausch, David Shade, Amy L. Gawad, Sabra L. Klein, Andrew Pekosz, Shmuel Shoham, Arturo Casadevall, Evan M. Bloch, Daniel Hanley, Aaron A. R. Tobian, David J. Sullivan
Summary: Early convalescent plasma transfusion can reduce the risk of hospitalization for COVID-19 patients, possibly by decreasing IL-6 levels and reducing disease severity.
MICROBIOLOGY SPECTRUM
(2023)
Letter
Emergency Medicine
Zhao-Yu Hsieh, Chen-Xiong Hsu
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Laura E. Walker, Jessica A. Stanich, Fernanda Bellolio
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
E. Tekin
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amanda S. Dupont, Patrick S. Walsh
Summary: Recent research indicates that children who unintentionally ingest cannabis often undergo extensive additional testing, such as head imaging or lumbar puncture. However, the yield of these tests is limited. While head imaging and lumbar puncture are frequently performed, diagnoses such as skull fracture, intracranial hemorrhage, intracranial neoplasm, meningitis, or intracranial abscess are rare. Additionally, discharge diagnoses related to other drugs are infrequent. The most common co-diagnoses are cocaine and opioids. Therefore, prompt consideration of cannabis ingestion and quick identification through testing may result in more effective neuroimaging outcomes.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Letter
Emergency Medicine
Mio Nagata, Shunsuke Kudo, Motoyasu Nakamura
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Andy Hung-Yi Lee, Katherine Dickerson Mayes, Regan Marsh, Christina Toledo-Cornell, Eric Goralnick, Michael Wilson, Leon D. Sanchez, Alice Bukhman, Damarcus Baymon, Dana Im, Paul C. Chen
Summary: This study assessed the disparities in transferring patients from an academic medical center emergency department to a community hospital general medical service, revealing healthcare disparities among different patient populations.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Annabelle Croskey, William Trautman, David Barton, Mary Kathleen Ratay, Joshua Shulman
Summary: This case report describes a successful management of ocular palytoxin exposure in a young male, highlighting the importance of prompt recognition and treatment of ocular PTX toxicity.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Matthew K. Kolbeck, Rachel F. Schult, Nicholas Nacca
Summary: This article presents four cases of adolescents who experienced seizures after acute fluoxetine overdose. Although seizures are an uncommon complication after fluoxetine overdose, they occurred in some patients at doses lower than those reported in the literature.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Editorial Material
Emergency Medicine
Daven Patel, John Bailitz, Simone Ymson, Jonas Neichin, Gary D. Peksa, Michael Gottlieb
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Amichai Gutgold, Shaden Salameh, Jeries Nashashibi, Yonatan Gershinsky
Summary: This study aimed to test the prognosis of patients with a pH lower than 6.9 on emergency department admission. The findings showed that a small but significant portion of these patients survived at least 24 hours and until hospital discharge.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Na-Yeon Emily Song, Ki Hong Kim, Ki Jeong Hong
Summary: This study aimed to evaluate the effect of the duration of no-flow (NF) interval on the vaso-pressor effect of initial epinephrine administration in a porcine model of cardiac arrest. The results showed that a shorter NF interval can enhance the vasopressor effect of epinephrine.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Kenneth A. Scheppke, Paul E. Pepe, Jonathan Jui, Remle P. Crowe, Eric K. Scheppke, Nancy G. Klimas, Aileen M. Marty
Summary: This study reported cases of rapid and complete remission of severe long COVID after receiving monoclonal antibody treatment. The findings suggest that monoclonal antibody infusions may be effective in treating severe debilitation caused by long COVID.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Suhrith Bhattaram, Varsha S. Shinde
Summary: Nerve blocks have emerged as promising options for targeted pain relief in the Emergency Department, providing effective analgesia without compromising motor function. The successful use of ultrasound-guided genicular nerve blocks (GNBs) in this case series demonstrates their potential as an alternative to traditional nerve blocks and opioid-based pain control strategies in the ED.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Rick Kye Gan, Jude Chukwuebuka Ogbodo, Yong Zheng Wee, Ann Zee Gan, Pedro Arcos Gonzalez
Summary: The aim of this study was to evaluate and compare the performance of ChatGPT, Google Bard, and medical students in performing START triage during mass casualty situations. The results showed that Google Bard had significantly higher accuracy compared to ChatGPT, while there was no significant difference between Google Bard and medical students.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)
Article
Emergency Medicine
Nancy Clemens, Paria M. Wilson, Matthew J. Lipshaw, Holly Depinet, Yin Zhang, Michelle Eckerle
Summary: This study compared clinical features and outcomes between pediatric sepsis patients with blood cultures positive versus negative for bacterial pathogens. The results showed that children with blood culture positive sepsis had higher rates of organ dysfunction, a larger base deficit, and higher procalcitonin levels.
AMERICAN JOURNAL OF EMERGENCY MEDICINE
(2024)