Article
Nutrition & Dietetics
Agata Witczak, Anna Pohorylo, Hassan Abdel-Gawad
Summary: The study assessed the safety of infants related to endocrine-disrupting organochlorine pesticides (OCP) in breast milk. It was found that certain dietary habits of pregnant mothers could affect the levels of OCP compounds in breast milk. The consumption of specific food products, such as pork, beef, poultry, eggs, and dairy, was linked to increased pesticide residues in breast milk.
Article
Nutrition & Dietetics
Isabel Ten-Domenech, Mari Merce Cascant-Vilaplana, Victor Navarro-Esteve, Birgit Felderer, Alba Moreno-Gimenez, Ivan Rienda, Maria Gormaz, Marta Moreno-Torres, David Perez-Guaita, Guillermo Quintas, Julia Kuligowski
Summary: This preliminary study aimed to characterize the cellular metabolome of human milk over the course of lactation. Cells were isolated and characterized, and their metabolites were analyzed using mass spectrometry. The results showed significant variations in the cellular composition and phenotypic properties of human milk during lactation. This study provides a basis for future investigations on the metabolomic fraction of the cellular compartment of human milk.
Article
Nutrition & Dietetics
Dominick J. Lemas, Xinsong Du, Bethany Dado-Senn, Ke Xu, Amanda Dobrowolski, Marina Magalhaes, Juan J. Aristizabal-Henao, Bridget E. Young, Magda Francois, Lindsay A. Thompson, Leslie A. Parker, Josef Neu, Jimena Laporta, Biswapriya B. Misra, Ismael Wane, Samih Samaan, Timothy J. Garrett
Summary: This study aims to identify unique metabolites that may impact infant health outcomes by analyzing the metabolome of human and bovine milk at 2 weeks of life. The results showed that more than 80% of the milk metabolome is shared between human and bovine milk during early lactation. These findings highlight untargeted metabolomics as a potential strategy to identify unique and shared metabolites in bovine and human milk that may relate to and impact infant health outcomes.
Article
Pediatrics
Margaret G. Parker, Lisa M. Stellwagen, Lawrence Noble, Jae H. Kim, Brenda B. Poindexter, Karen M. Puopolo
Summary: Providing mother's own milk for hospitalized very low birth weight infants in the NICU has short- and long-term health benefits. When mother's own milk is not available, pasteurized human donor milk is recommended as an alternative. Neonatal health care providers can support lactation in the NICU to reduce disparities in provision of mother's own milk.
Article
Food Science & Technology
Chiara Peila, Stefano Sottemano, Flaminia Cesare Marincola, Matteo Stocchero, Nicoletta Grazia Pusceddu, Angelica Dessi, Eugenio Baraldi, Vassilios Fanos, Enrico Bertino
Summary: This study longitudinally investigated the metabolome of milk from women delivering preterm at different gestational ages. The study found that both the mother's phenotype and lactation time had a significant impact on the metabolome composition of human milk. Additionally, statistically significant differences in terms of gestational age were observed. These findings provide insights into optimizing feeding and improving outcomes for preterm newborns.
Article
Pharmacology & Pharmacy
Natalie Dinavitser, Elkana Kohn, Maya Berlin, Nurit Brandriss, Adina Bar-Chaim, Rimona Keidar, Ayelet Livne, David Stepensky, Matitiahu Berkovitch, Revital Sheinberg
Summary: This study examined the excretion of levetiracetam in breastmilk in breastfeeding women with epilepsy, finding that exposure to the drug in breastmilk may lead to infant toxicities. The study also revealed a close correlation between levetiracetam dose, maternal serum concentration, and breastmilk levels. Further studies are needed to assess the short- and long-term safety of levetiracetam in breastfeeding infants.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY
(2022)
Review
Microbiology
Sophie I. S. Wedekind, Natalie S. Shenker
Summary: Humans have always coexisted with viruses, and evolutionary pressure has shaped the intrinsic properties of lactation and milk to support the neonate's immune system and protect against pathogens. Human milk contains specific components that support immune learning and maturation, as well as provide direct protection against microorganisms. However, there is a lack of awareness among the public and healthcare professionals about the specific antiviral properties of human milk beyond the production of maternal antibodies.
Article
Nursing
Katherine R. Standish, Ginny Combs, Marcy Mcmahon, Cheryl Slater, Lisa Zani, Christina Pindar, Karol Serafin, Margaret G. Parker, Barbara L. Philipp
Summary: Late preterm infants have lower breastfeeding rates and there are few interventions or guidelines for managing them in non-intensive nursery settings. This study developed and implemented an interdisciplinary breastfeeding support program, which increased nurses' attentiveness and confidence in caring for late preterm infants. However, well-designed clinical studies are needed to identify effective breastfeeding support practices.
JOURNAL OF HUMAN LACTATION
(2023)
Article
Nutrition & Dietetics
Laurentya Olga, Janna A. van Diepen, Maciej Chichlowski, Clive J. Petry, Jacques Vervoort, David B. Dunger, Guus A. M. Kortman, Gabriele Gross, Ken K. Ong
Summary: This study investigated the origins and determining factors of butyrate in human milk and its influence on infant weight gain. The results showed that higher concentrations of butyrate in human milk were associated with lower infant weight and adiposity, especially in younger infants. Furthermore, the study found an inverse correlation between butyrate concentration and milk intake volume, suggesting a potential mechanism involving appetite regulation and modulation of milk intake.
Article
Nursing
Kameron Y. Sugino, Tengfei Ma, Jean M. Kerver, Nigel Paneth, Sarah S. Comstock
Summary: This study found that maternal pre-pregnancy BMI and human milk exposure influenced the alpha and beta diversity of the infant gut microbiota at 6 months of age. The major determinant was the proportion of human milk in the infant diet.
JOURNAL OF HUMAN LACTATION
(2021)
Article
Multidisciplinary Sciences
Alecia-Jane Twigger, Lisa K. Engelbrecht, Karsten Bach, Isabel Schultz-Pernice, Sara Pensa, Jack Stenning, Stefania Petricca, Christina H. Scheel, Walid T. Khaled
Summary: This study characterizes cells in human milk and identifies epithelial cells similar to luminal progenitors and immune cells. The findings contribute to understanding the remodelling of human mammary tissue during pregnancy and lactation, and provide insights into the interplay between pregnancy, lactation, and breast cancer.
NATURE COMMUNICATIONS
(2022)
Article
Obstetrics & Gynecology
Abigail Liberty, Elizabeth S. Rubin, Kimberley A. Bullard, Katherine Au
Summary: Lactation is a powerful tool for improving health trajectories and promoting reproductive justice. Various human milk-expression technologies, including pumps and accessories, can help patients establish and maintain breastfeeding. Understanding and counseling patients about these technologies is important for physicians in supporting patients' feeding goals.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Nutrition & Dietetics
Elena Sinkiewicz-Darol, Urszula Bernatowicz-Lojko, Katarzyna Lubiech, Iwona Adamczyk, Magdalena Twaruzek, Barbara Baranowska, Krzysztof Skowron, Diane L. Spatz
Summary: This study found that milk from tandem breastfeeding mothers had higher fat content, energy value, and total protein concentration compared to milk after weaning, while the carbohydrate content remained stable. The composition of breastmilk changes after weaning to meet the nutritional requirements of the younger child.
Article
Food Science & Technology
Tinglan Yuan, Wei Wei, Xinghe Zhang, Lei Wang, Xinyue Dai, Cuirong Ren, Xingguo Wang, Qingzhe Jin
Summary: This study compared the MCFA and MLCT profiles in human milk from mothers after preterm and term delivery. The results showed that almost half of the triacylglycerol species in human milk are MLCT, mainly composed of one MCFA and two long-chain fatty acids. The research found that MCFAs and MLCTs have different changes in different lactational stages.
LWT-FOOD SCIENCE AND TECHNOLOGY
(2021)
Article
Pediatrics
Elisenda Moliner-Calderon, Sergio Verd, Alfonso Leiva, Jaume Ponce-Taylor, Gemma Ginovart, Pia Moll-McCarthy, Catian Gelabert, Josep Figueras-Aloy
Summary: This study aimed to compare the need for mechanical ventilation between neonates with sepsis who were fed human milk and those who were fed formula. The results showed that human milk-fed neonates required less respiratory support and invasive mechanical ventilation compared to their formula-fed counterparts.
Review
Nutrition & Dietetics
Ramkripa Raghavan, Carol Dreibelbis, Brittany L. Kingshipp, Yat Ping Wong, Barbara Abrams, Alison D. Gernand, Kathleen M. Rasmussen, Anna Maria Siega-Riz, Jamie Stang, Kellie O. Casavale, Joanne M. Spahn, Eve E. Stoody
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2019)
Article
Nutrition & Dietetics
Siraphat Taesuwan, Francoise Vermeylen, Marie A. Caudill, Patricia A. Cassano
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2019)
Article
Nutrition & Dietetics
Muna J. Tahir, Jacob L. Haapala, Laurie P. Foster, Katy M. Duncan, April M. Teague, Elyse O. Kharbanda, Patricia M. McGovern, Kara M. Whitaker, Kathleen M. Rasmussen, David A. Fields, David R. Jacobs, Lisa J. Harnack, Ellen W. Demerath
Review
Nutrition & Dietetics
Ramkripa Raghavan, Carol Dreibelbis, Brittany L. Kingshipp, Yat Ping Wong, Barbara Abrams, Alison D. Gernand, Kathleen M. Rasmussen, Anna Maria Siega-Riz, Jamie Stang, Kellie O. Casavale, Joanne M. Spahn, Eve E. Stoody
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2019)
Article
Nutrition & Dietetics
Muna J. Tahir, Jacob L. Haapala, Laurie P. Foster, Katy M. Duncan, April M. Teague, Elyse O. Kharbanda, Patricia M. McGovern, Kara M. Whitaker, Kathleen M. Rasmussen, David A. Fields, Lisa J. Harnack, David R. Jacobs, Ellen W. Demerath
Editorial Material
Nutrition & Dietetics
Kathleen M. Rasmussen
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2019)
Editorial Material
Medicine, General & Internal
Lars Ake Persson, Kathleen M. Rasmussen, Huixia Yang
Article
Nutrition & Dietetics
Dorthe C. Pedersen, Lise G. Bjerregaard, Ellen A. Nohr, Kathleen M. Rasmussen, Jennifer L. Baker
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2020)
Article
Medicine, General & Internal
Helene Kirkegaard, Mette Bliddal, Henrik Stovring, Kathleen M. Rasmussen, Erica P. Gunderson, Lars Kober, Thorkild I. A. Sorensen, Ellen A. Nohr
Summary: This study found that postpartum weight retention or new gain in all mothers, as well as weight loss in mothers with normal-/underweight, may be associated with adverse cardiovascular health in the future. It is suggested that healthcare professionals pay attention to postpartum weight change patterns to improve cardiovascular health.
Article
Nutrition & Dietetics
Thais Rangel Bousquet Carrilho, Kathleen M. Rasmussen, Jennifer A. Hutcheon, Ronaldo Fernandes Santos Alves, Dayana Rodrigues Farias, Nathalia Cristina Freitas-Costa, Mylena Maciel Gonzalez, Monica Araujo Batalha, Gilberto Kac
Summary: This study examined prepregnancy body mass index (BMI) and gestational weight gain (GWG) of 840,243 women in Brazil from 2008 to 2018, showing an increase in rates of prepregnancy overweight, obesity, and excessive GWG. The findings revealed that women with underweight had the highest mean total GWG values, while women with different BMI statuses had varying levels of GWG.
MATERNAL AND CHILD NUTRITION
(2022)
Article
Nutrition & Dietetics
Dorthe C. Pedersen, Lise G. Bjerregaard, Kathleen M. Rasmussen, Ellen A. Nohr, Jennifer L. Baker
Summary: This study found that maternal birth weight, childhood height, and BMI are associated with risks of preterm delivery. Childhood BMI has a U-shaped association, and short stature in childhood and adulthood is associated with higher risks of preterm delivery. Normalizing BMI from childhood to pregnancy may reduce the risk of very preterm delivery.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Cardiac & Cardiovascular Systems
Christina M. Eckhardt, Pallavi P. Balte, Robert Graham Barr, Alain G. Bertoni, Surya P. Bhatt, Michael Cuttica, Patricia A. Cassano, Paolo Chaves, David Couper, David R. Jacobs, Ravi Kalhan, Richard Kronmal, Leslie Lange, Laura Loehr, Stephanie J. London, George T. O'Connor, Wayne Rosamond, Jason Sanders, Joseph E. Schwartz, Amil Shah, Sanjiv J. Shah, Lewis Smith, Wendy White, Sachin Yende, Elizabeth C. Oelsner
Summary: The study found that lung function impairment was associated with an increased risk of incident heart failure, particularly in relation to HFpEF. This association was independent and of a similar magnitude to major cardiovascular risk factors.
EUROPEAN HEART JOURNAL
(2022)
Article
Nutrition & Dietetics
Dayana R. Farias, Thais R. B. Carrilho, Kathleen M. Rasmussen, Jennifer A. Hutcheon, Michael E. Reichenheim, Denise C. Barros, Silvana G. N. da Gama, Gilberto Kac
Summary: There are differences in GWG trajectories among different charts, especially for women with overweight and obesity. The four charts showed low predictive ability for SGA and LGA births.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Nutrition & Dietetics
Jennifer A. Peregoy, Giovana M. Pinheiro, Sheela R. Geraghty, Katherine L. Dickin, Kathleen M. Rasmussen
Summary: This study describes and compares the infant-feeding behaviors and human milk sharing practices among donors and recipients. The results show that recipients face more maternal health challenges, but are still able to achieve a long duration of human milk feeding. However, further research is needed to investigate the associations between human milk sharing participation, infant-feeding behaviors, and lactation outcomes.
MATERNAL AND CHILD NUTRITION
(2022)
Review
Medicine, General & Internal
Sajin Bae, Elena Kamynina, Heather M. Guetterman, Adetutu F. Farinola, Marie A. Caudill, Robert J. Berry, Patricia A. Cassano, Patrick J. Stover
Summary: The provision of folic acid supplements may benefit blood arsenic concentration, urinary arsenic methylation profiles, and plasma homocysteine concentration versus placebo with moderate-certainty evidence. Furthermore, there is low-certainty evidence that folic acid supplements plus other nutrients may benefit blood arsenic and plasma homocysteine concentrations versus nutrients alone. Given the limited number of studies, more research is needed to assess the effects of folic acid on arsenic-related health outcomes in diverse settings.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2021)