Crocin-Elicited Autophagy Rescues Myocardial Ischemia/Reperfusion Injury via Paradoxical Mechanisms

The role of autophagy during ischemia/reperfusion

(2014) Junichi Sadoshima   Autophagy

NADPH oxidase 4 promotes cardiac microvascular angiogenesis after hypoxia/reoxygenation in vitro

(2014) Jinyi Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Protective Effects of Crocin on Hemodynamic Parameters and Infarct Size in Comparison with Vitamin E after Ischemia Reperfusion in Isolated Rat Hearts

(2014) Mahin Dianat et al.   PLANTA MEDICA

Combination of D942 With Curcumin Protects Cardiomyocytes From Ischemic Damage Through Promoting Autophagy

(2013) Keping Yang et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Autophagy in Human Health and Disease

(2013) Augustine M.K. Choi et al.   NEW ENGLAND JOURNAL OF MEDICINE

Ginsenoside Rd Attenuates Myocardial Ischemia/Reperfusion Injury via Akt/GSK-3β Signaling and Inhibition of the Mitochondria-Dependent Apoptotic Pathway

(2013) Yang Wang et al.   PLoS One

A dietary colorant crocin mitigates arthritis and associated secondary complications by modulating cartilage deteriorating enzymes, inflammatory mediators and antioxidant status

(2012) M. Hemshekhar et al.   BIOCHIMIE

Crocin prevents retinal ischaemia/reperfusion injury-induced apoptosis in retinal ganglion cells through the PI3K/AKT signalling pathway

(2012) Yun Qi et al.   EXPERIMENTAL EYE RESEARCH

Curcumin Alleviates Diabetic Cardiomyopathy in Experimental Diabetic Rats

(2012) Wei Yu et al.   PLoS One

Chronic akt activation accentuates aging-induced cardiac hypertrophy and myocardial contractile dysfunction: role of autophagy

(2011) Yinan Hua et al.   BASIC RESEARCH IN CARDIOLOGY

Autophagy as a therapeutic target in cancer

(2011) Ning Chen et al.   CANCER BIOLOGY & THERAPY

Akt/GSK-3β/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia–reperfusion injury in rats

(2011) Saurabh Bharti et al.   EUROPEAN JOURNAL OF NUTRITION

Pathogenesis of Myocardial Ischemia-Reperfusion Injury and Rationale for Therapy

(2010) Aslan T. Turer et al.   AMERICAN JOURNAL OF CARDIOLOGY

Oxidative Stress Stimulates Autophagic Flux During Ischemia/Reperfusion

(2010) Nirmala Hariharan et al.   ANTIOXIDANTS & REDOX SIGNALING

Crocetin prevents retinal degeneration induced by oxidative and endoplasmic reticulum stresses via inhibition of caspase activity

(2010) Mika Yamauchi et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Is Autophagy in Response to Ischemia and Reperfusion Protective or Detrimental for the Heart?

(2010) Sebastiano Sciarretta et al.   PEDIATRIC CARDIOLOGY

The role of AMP-activated protein kinase in the cardiovascular system

(2009) Daisuke Nagata et al.   HYPERTENSION RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE