The Roles of 4β-Hydroxywithanolide E from Physalis peruviana on the Nrf2-Anti-Oxidant System and the Cell Cycle in Breast Cancer Cells

Resveratrol inhibits estrogen-induced breast carcinogenesis through induction of NRF2-mediated protective pathways

(2014) Bhupendra Singh et al.   CARCINOGENESIS

Ligation of CD47 Induces G1 Arrest in EBV-transformed B Cells Through ROS Generation, p38 MAPK/JNK Activation, and Tap73 Upregulation

(2014) Ga Bin Park et al.   JOURNAL OF IMMUNOTHERAPY

Curcumin inhibits proliferation of breast cancer cells through Nrf2-mediated down-regulation of Fen1 expression

(2014) Bin Chen et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Oncogenic transformation of mesenchymal stem cells decreases Nrf2 expression favoring in vivo tumor growth and poorer survival

(2014) Juan M Funes et al.   Molecular Cancer

HER2 confers drug resistance of human breast cancer cells through activation of NRF2 by direct interaction

(2014) Hyo Jin Kang et al.   Scientific Reports

NRF2 immunolocalization in human breast cancer patients as a prognostic factor

(2013) Yoshiaki Onodera et al.   ENDOCRINE-RELATED CANCER

Non-homologous end joining pathway is the major route of protection against 4β-hydroxywithanolide E-induced DNA damage in MCF-7 cells

(2013) B.-J. You et al.   FOOD AND CHEMICAL TOXICOLOGY

Thymoquinone induces heme oxygenase-1 expression in HaCaT cells via Nrf2/ARE activation: Akt and AMPKα as upstream targets

(2013) Juthika Kundu et al.   FOOD AND CHEMICAL TOXICOLOGY

Diabetic Downregulation of Nrf2 Activity via ERK Contributes to Oxidative Stress-Induced Insulin Resistance in Cardiac Cells In Vitro and In Vivo

(2011) Y. Tan et al.   DIABETES

The Heme Oxygenase-1 Protein Is Overexpressed in Human Renal Cancer Cells following Activation of the Ras-Raf-ERK Pathway and Mediates Anti-Apoptotic Signal

(2011) Pallavi Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy

(2011) Adam Lister et al.   Molecular Cancer

Sense and Sensitivity: FOXO and ROS in Cancer Development and Treatment

(2010) Stephen S. Myatt et al.   ANTIOXIDANTS & REDOX SIGNALING

Involvement of Nrf2 activation in resistance to 5-fluorouracil in human colon cancer HT-29 cells

(2009) Hanane Akhdar et al.   EUROPEAN JOURNAL OF CANCER

Overexpression of catalase delays G0/G1- to S-phase transition during cell cycle progression in mouse aortic endothelial cells

(2009) Ogbeyalu E. Onumah et al.   FREE RADICAL BIOLOGY AND MEDICINE

Cul3 overexpression depletes Nrf2 in breast cancer and is associated with sensitivity to carcinogens, to oxidative stress, and to chemotherapy

(2009) M. Loignon et al.   MOLECULAR CANCER THERAPEUTICS

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

(2009) Dunyaporn Trachootham et al.   NATURE REVIEWS DRUG DISCOVERY

Nrf2 signaling and cell survival

(2009) Suryakant K. Niture et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Activation of Nrf2-antioxidant signaling attenuates NFκB-inflammatory response and elicits apoptosis

(2008) Wenge Li et al.   BIOCHEMICAL PHARMACOLOGY

Oxidative stress involvement in Physalis angulata-induced apoptosis in human oral cancer cells

(2008) H.-Z. Lee et al.   FOOD AND CHEMICAL TOXICOLOGY

Increased expression of Nrf2/ARE-dependent anti-oxidant proteins in tamoxifen-resistant breast cancer cells

(2008) Sang Kyum Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells

(2008) Eun Jeong Choi et al.   PHYTOMEDICINE