With or without rafts? Alternative views on cell membranes

Transbilayer Lipid Interactions Mediate Nanoclustering of Lipid-Anchored Proteins

(2015) Riya Raghupathy et al.   CELL

Cholesterol under oxidative stress—How lipid membranes sense oxidation as cholesterol is being replaced by oxysterols

(2015) Waldemar Kulig et al.   FREE RADICAL BIOLOGY AND MEDICINE

Barriers to the free diffusion of proteins and lipids in the plasma membrane

(2015) William S. Trimble et al.   JOURNAL OF CELL BIOLOGY

Membrane potential modulates plasma membrane phospholipid dynamics and K-Ras signaling

(2015) Y. Zhou et al.   SCIENCE

GPI-anchored proteins do not reside in ordered domains in the live cell plasma membrane

(2015) Eva Sevcsik et al.   Nature Communications

The basic structure and dynamics of cell membranes: An update of the Singer–Nicolson model

(2014) Félix M. Goñi   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Time-Resolved Fluorescence in Lipid Bilayers: Selected Applications and Advantages over Steady State

(2014) Mariana Amaro et al.   BIOPHYSICAL JOURNAL

Peripheral and Integral Membrane Binding of Peptides Characterized by Time-Dependent Fluorescence Shifts: Focus on Antimicrobial Peptide LAH4

(2014) Radek Macháň et al.   LANGMUIR

Golgi sorting regulates organization and activity of GPI proteins at apical membranes

(2014) Simona Paladino et al.   Nature Chemical Biology

Dynamic Shaping of Cellular Membranes by Phospholipids and Membrane-Deforming Proteins

(2014) Shiro Suetsugu et al.   PHYSIOLOGICAL REVIEWS

Enzymatic Oxidation of Cholesterol: Properties and Functional Effects of Cholestenone in Cell Membranes

(2014) Maarit Neuvonen et al.   PLoS One

H-Ras forms dimers on membrane surfaces via a protein-protein interface

(2014) W.-C. Lin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stable Cell Surface Expression of GPI-Anchored Proteins, but not Intracellular Transport, Depends on their Fatty Acid Structure

(2014) Nina Jaensch et al.   TRAFFIC

Scanning STED-FCS reveals spatiotemporal heterogeneity of lipid interaction in the plasma membrane of living cells

(2014) Alf Honigmann et al.   Nature Communications

Multi-protein assemblies underlie the mesoscale organization of the plasma membrane

(2014) Sinem K. Saka et al.   Nature Communications

Molecular lipidomics of exosomes released by PC-3 prostate cancer cells

(2013) Alicia Llorente et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

When peers are not peers and don't know it: The Dunning-Kruger effect and self-fulfilling prophecy in peer-review

(2013) Sui Huang   BIOESSAYS

Sphingolipid Domains in the Plasma Membranes of Fibroblasts Are Not Enriched with Cholesterol

(2013) Jessica F. Frisz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Steric Pressure between Membrane-Bound Proteins Opposes Lipid Phase Separation

(2013) Christine S. Scheve et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Plasma membrane organization and function: moving past lipid rafts

(2013) Mary L. Kraft   MOLECULAR BIOLOGY OF THE CELL

Direct chemical evidence for sphingolipid domains in the plasma membranes of fibroblasts

(2013) J. F. Frisz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Large effect of membrane tension on the fluid-solid phase transitions of two-component phosphatidylcholine vesicles

(2013) D. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How cholesterol interacts with membrane proteins: an exploration of cholesterol-binding sites including CRAC, CARC, and tilted domains

(2013) Jacques Fantini et al.   Frontiers in Physiology

Phosphoinositides and vesicular membrane traffic

(2012) Peter Mayinger   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Active Remodeling of Cortical Actin Regulates Spatiotemporal Organization of Cell Surface Molecules

(2012) Kripa Gowrishankar et al.   CELL

Monitoring Lipid Anchor Organization in Cell Membranes by PIE-FCCS

(2012) Sara B. Triffo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Molecular recognition of a single sphingolipid species by a protein’s transmembrane domain

(2012) F.-Xabier Contreras et al.   NATURE

Membrane bending by protein–protein crowding

(2012) Jeanne C. Stachowiak et al.   NATURE CELL BIOLOGY

Transient GPI-anchored protein homodimers are units for raft organization and function

(2012) Kenichi G N Suzuki et al.   Nature Chemical Biology

Elucidating membrane structure and protein behavior using giant plasma membrane vesicles

(2012) Erdinc Sezgin et al.   Nature Protocols

A critical survey of methods to detect plasma membrane rafts

(2012) E. Klotzsch et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Cholesterol increases kinetic, energetic, and mechanical stability of the human  2-adrenergic receptor

(2012) M. Zocher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PI4P and PI(4,5)P2 Are Essential But Independent Lipid Determinants of Membrane Identity

(2012) G. R. V. Hammond et al.   SCIENCE

Sub-resolution lipid domains exist in the plasma membrane and regulate protein diffusion and distribution

(2012) Dylan M. Owen et al.   Nature Communications

Cholesterol modulates cell signaling and protein networking by specifically interacting with PDZ domain-containing scaffold proteins

(2012) Ren Sheng et al.   Nature Communications

Structural Characterization of the Caveolin Scaffolding Domain in Association with Cholesterol-Rich Membranes

(2011) Cody L. Hoop et al.   BIOCHEMISTRY

STED Nanoscopy Reveals Molecular Details of Cholesterol- and Cytoskeleton-Modulated Lipid Interactions in Living Cells

(2011) V. Mueller et al.   BIOPHYSICAL JOURNAL

Measurement of Lipid Nanodomain (Raft) Formation and Size in Sphingomyelin/POPC/Cholesterol Vesicles Shows TX-100 and Transmembrane Helices Increase Domain Size by Coalescing Preexisting Nanodomains But Do Not Induce Domain Formation

(2011) Priyadarshini Pathak et al.   BIOPHYSICAL JOURNAL

Osh Proteins Regulate Phosphoinositide Metabolism at ER-Plasma Membrane Contact Sites

(2011) Christopher J. Stefan et al.   CELL

Structures, Biosynthesis, and Functions of Gangliosides-an Overview

(2011) Robert K. Yu et al.   Journal of Oleo Science

Gag Induces the Coalescence of Clustered Lipid Rafts and Tetraspanin-Enriched Microdomains at HIV-1 Assembly Sites on the Plasma Membrane

(2011) I. B. Hogue et al.   JOURNAL OF VIROLOGY

N-Glycosylation instead of cholesterol mediates oligomerization and apical sorting of GPI-APs in FRT cells

(2011) Naga Salaija Imjeti et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane protein sequestering by ionic protein–lipid interactions

(2011) Geert van den Bogaart et al.   NATURE

Structural basis of PIP2 activation of the classical inward rectifier K+ channel Kir2.2

(2011) Scott B. Hansen et al.   NATURE

Probing protein heterogeneity in the plasma membrane using PALM and pair correlation analysis

(2011) Prabuddha Sengupta et al.   NATURE METHODS

Raft domains of variable properties and compositions in plasma membrane vesicles

(2011) I. Levental et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lateral sorting in model membranes by cholesterol-mediated hydrophobic matching

(2011) H.-J. Kaiser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Staying in touch: the molecular era of organelle contact sites

(2011) Yael Elbaz et al.   TRENDS IN BIOCHEMICAL SCIENCES

Hierarchical mesoscale domain organization of the plasma membrane

(2011) Akihiro Kusumi et al.   TRENDS IN BIOCHEMICAL SCIENCES

Specificity of Intramembrane Protein-Lipid Interactions

(2011) F.-X. Contreras et al.   Cold Spring Harbor Perspectives in Biology

Lipid-Mediated Endocytosis

(2011) H. Ewers et al.   Cold Spring Harbor Perspectives in Biology

Pressure effect on the bilayer phase transition of asymmetric lipids with an unsaturated acyl chain

(2010) Kaori Tada et al.   Annals of the New York Academy of Sciences

Temperature-dependent phase behavior and protein partitioning in giant plasma membrane vesicles

(2010) S.A. Johnson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

The liquid-ordered state comes of age

(2010) Ole G. Mouritsen   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Laurdan and di-4-ANEPPDHQ do not respond to membrane-inserted peptides and are good probes for lipid packing

(2010) Jelena Dinic et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Imaging of Mobile Long-lived Nanoplatforms in the Live Cell Plasma Membrane

(2010) Mario Brameshuber et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Membrane Proteins Diffuse as Dynamic Complexes with Lipids

(2010) Perttu S. Niemelä et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Revitalizing membrane rafts: new tools and insights

(2010) Kai Simons et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Direct mapping of nanoscale compositional connectivity on intact cell membranes

(2010) T. S. van Zanten et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dynamic sorting of lipids and proteins in membrane tubes with a moving phase boundary

(2010) M. Heinrich et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Palmitoylation regulates raft affinity for the majority of integral raft proteins

(2010) I. Levental et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lipids and Membrane Lateral Organization

(2010) Sandro Sonnino et al.   Frontiers in Physiology

Cell membrane extensions, generated by mechanical constraint, are associated with a sustained lipid raft patching and an increased cell signaling

(2009) Romain M. Larive et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Calcium-Actin Waves and Oscillations of Cellular Membranes

(2009) Alex Veksler et al.   BIOPHYSICAL JOURNAL

Two-color single molecule tracking combined with photobleaching for the detection of rare molecular interactions in fluid biomembranes

(2009) Verena Ruprecht et al.   Soft Matter

The Glycosylphosphatidylinositol Anchor: A Complex Membrane-Anchoring Structure for Proteins†

(2008) Margot G. Paulick et al.   BIOCHEMISTRY

Protein modulation of lipids, and vice-versa, in membranes

(2008) Derek Marsh   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Atom-scale molecular interactions in lipid raft mixtures

(2008) Perttu S. Niemelä et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Nanoclusters of GPI-Anchored Proteins Are Formed by Cortical Actin-Driven Activity

(2008) Debanjan Goswami et al.   CELL

Have we become overly reliant on lipid rafts? Talking Point on the involvement of lipid rafts in T-cell activation

(2008) Anne K Kenworthy   EMBO REPORTS

Patching of gangliosideM1in human erythrocytes – distribution of CD47 and CD59 in patched and curved membrane

(2008) Lucyna Mrówczyńska et al.   MOLECULAR MEMBRANE BIOLOGY

Direct observation of the nanoscale dynamics of membrane lipids in a living cell

(2008) Christian Eggeling et al.   NATURE

Membrane lipids: where they are and how they behave

(2008) Gerrit van Meer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Protein area occupancy at the center of the red blood cell membrane

(2008) A. D. Dupuy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Phosphatidylserine Regulates Surface Charge and Protein Localization

(2008) T. Yeung et al.   SCIENCE

Informatics and computational strategies for the study of lipids

(2007) Laxman Yetukuri et al.   Molecular BioSystems