Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles

Induction of Hyperhomocysteinemia Models Vascular Dementia by Induction of Cerebral Microhemorrhages and Neuroinflammation

(2013) Tiffany L Sudduth et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Gene knockout of 5-lipoxygenase rescues synaptic dysfunction and improves memory in the triple-transgenic model of Alzheimer's disease

(2013) P F Giannopoulos et al.   MOLECULAR PSYCHIATRY

Zileuton Improves Memory Deficits, Amyloid and Tau Pathology in a Mouse Model of Alzheimer’s Disease with Plaques and Tangles

(2013) Jin Chu et al.   PLoS One

Lifelong Management of Amyloid-Beta Metabolism to Prevent Alzheimer's Disease

(2012) Sam Gandy   NEW ENGLAND JOURNAL OF MEDICINE

Is hyperhomocysteinemia an Alzheimer's disease (AD) risk factor, an AD marker, or neither?

(2011) Jia-Min Zhuo et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Diet-Induced Hyperhomocysteinemia Increases Amyloid-β Formation and Deposition in a Mouse Model of Alzheimers Disease

(2010) J.-M. Zhuo et al.   Current Alzheimer Research

Acceleration of brain amyloidosis in an Alzheimer’s disease mouse model by a folate, vitamin B6 and B12-deficient diet

(2009) Jia-Min Zhuo et al.   EXPERIMENTAL GERONTOLOGY

Homocysteine-induced acute excitotoxicity in cerebellar granule cells in vitro is accompanied by PP2A-mediated dephosphorylation of tau

(2009) Magdalena Kuszczyk et al.   NEUROCHEMISTRY INTERNATIONAL

Hyperhomocysteinemia and Alzheimer's disease: A systematic review

(2008) Floris Van Dam et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

High-Dose B Vitamin Supplementation and Cognitive Decline in Alzheimer Disease

(2008) Paul S. Aisen   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Blocking A 42 Accumulation Delays the Onset and Progression of Tau Pathology via the C Terminus of Heat Shock Protein70-Interacting Protein: A Mechanistic Link between A  and Tau Pathology

(2008) S. Oddo et al.   JOURNAL OF NEUROSCIENCE

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-β deposition in mice

(2008) Andrea Fuso et al.   MOLECULAR AND CELLULAR NEUROSCIENCE