Pharmacokinetics and Safety of Triple Therapy with Vonoprazan, Amoxicillin, and Clarithromycin or Metronidazole: A Phase 1, Open-Label, Randomized, Crossover Study
Published 2016 View Full Article
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Title
Pharmacokinetics and Safety of Triple Therapy with Vonoprazan, Amoxicillin, and Clarithromycin or Metronidazole: A Phase 1, Open-Label, Randomized, Crossover Study
Authors
Keywords
Drug interactions, Gastroenterology, <em class=EmphasisTypeItalic >Helicobacter pylori</em>, Pharmacokinetics, Potassium-competitive acid blocker, Safety, TAK-438, Triple therapy, Vonoprazan
Journal
ADVANCES IN THERAPY
Volume 33, Issue 9, Pages 1519-1535
Publisher
Springer Nature
Online
2016-07-18
DOI
10.1007/s12325-016-0374-x
References
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- Randomised clinical trial: safety, tolerability, pharmacokinetics and pharmacodynamics of repeated doses of TAK-438 (vonoprazan), a novel potassium-competitive acid blocker, in healthy male subjects
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- Randomised clinical trial: a dose-ranging study of vonoprazan, a novel potassium-competitive acid blocker, vs. lansoprazole for the treatment of erosive oesophagitis
- (2015) K. Ashida et al. ALIMENTARY PHARMACOLOGY & THERAPEUTICS
- Potassium-Competitive Acid Blockers (P-CABs): Are They Finally Ready for Prime Time in Acid-Related Disease?
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- Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising TAK-438 (Vonoprazan) Doses in Healthy Male Japanese/non-Japanese Subjects
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- Management ofHelicobacter pyloriinfection—the Maastricht IV/ Florence Consensus Report
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- 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438), a Novel and Potent Potassium-Competitive Acid Blocker for the Treatment of Acid-Related Diseases
- (2010) Y. Hori et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Safety of the long-term use of proton pump inhibitors
- (2010) Alan BR Thomson WORLD JOURNAL OF GASTROENTEROLOGY
- Acid peptic diseases: pharmacological approach to treatment
- (2009) Alex Mejia et al. Expert Review of Clinical Pharmacology
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