Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Rising TAK-438 (Vonoprazan) Doses in Healthy Male Japanese/non-Japanese Subjects

Pathophysiology of Gastroesophageal Reflux Disease

(2014) Guy E. Boeckxstaens et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Epidemiology of Gastroesophageal Reflux Disease

(2014) Joel H. Rubenstein et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Acid and Nonacid Reflux Monitoring

(2014) Dustin A. Carlson et al.   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Efficacy of TailoredHelicobacter pyloriEradication Treatment Based on Clarithromycin Susceptibility and Maintenance of Acid Secretion

(2014) Mitsushige Sugimoto et al.   HELICOBACTER

A Randomized, Comparative Trial of a Potassium-Competitive Acid Blocker (AZD0865) and Esomeprazole for the Treatment of Patients With Nonerosive Reflux Disease

(2013) John Dent et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The effects of varying acidity onHelicobacter pylorigrowth and the bactericidal efficacy of ampicillin

(2012) E. A. Marcus et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Discovery, synthesis, and biological evaluation of novel pyrrole derivatives as highly selective potassium-competitive acid blockers

(2012) Haruyuki Nishida et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Discovery of a Novel Pyrrole Derivative 1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Fumarate (TAK-438) as a Potassium-Competitive Acid Blocker (P-CAB)

(2012) Yasuyoshi Arikawa et al.   JOURNAL OF MEDICINAL CHEMISTRY

An open-label, parallel, multiple-dose study comparing the pharmacokinetics and gastric acid suppression of rabeprazole extended-release with esomeprazole 40 mg and rabeprazole delayed-release 20 mg in healthy volunteers

(2011) G. Morelli et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

A comparative study on the modes of action of TAK-438, a novel potassium-competitive acid blocker, and lansoprazole in primary cultured rabbit gastric glands

(2011) Jun Matsukawa et al.   BIOCHEMICAL PHARMACOLOGY

A Study Comparing the Antisecretory Effect of TAK-438, a Novel Potassium-Competitive Acid Blocker, with Lansoprazole in Animals

(2011) Y. Hori et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

The effects of dose and timing of esomeprazole administration on 24-h, daytime and night-time acid inhibition in healthy volunteers

(2010) C. Wilder-Smith et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

1-[5-(2-Fluorophenyl)-1-(pyridin-3-ylsulfonyl)-1H-pyrrol-3-yl]-N-methylmethanamine Monofumarate (TAK-438), a Novel and Potent Potassium-Competitive Acid Blocker for the Treatment of Acid-Related Diseases

(2010) Y. Hori et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Review article: strategies to determine whether hypergastrinaemia is due to Zollinger-Ellison syndrome rather than a more common benign cause

(2009) S. V. M. MURUGESAN et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Review article: sleep-related gastro-oesophageal reflux as a distinct clinical entity

(2009) W. C. ORR   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Differences in Peptic Ulcer Between the East and the West

(2009) Rupert W. Leong   GASTROENTEROLOGY CLINICS OF NORTH AMERICA

Acid peptic diseases: pharmacological approach to treatment

(2009) Alex Mejia et al.   Expert Review of Clinical Pharmacology

A Systematic Review of the Definitions, Prevalence, and Response to Treatment of Nocturnal Gastroesophageal Reflux Disease

(2008) Lauren B. Gerson et al.   Clinical Gastroenterology and Hepatology

Gastric Mucosal Defense and Cytoprotection: Bench to Bedside

(2008) Loren Laine et al.   GASTROENTEROLOGY

Control of Gastric Acid Secretion in Health and Disease

(2008) Mitchell L. Schubert et al.   GASTROENTEROLOGY

Measurement of gastric pH in ambulatory esophageal pH monitoring

(2008) Shahin Ayazi et al.   SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES