Bio-Inspired Mechanotactic Hybrids for Orchestrating Traction-Mediated Epithelial Migration

A molecular mechanotransduction pathway regulates collective migration of epithelial cells

(2015) Tamal Das et al.   NATURE CELL BIOLOGY

Electronic dura mater for long-term multimodal neural interfaces

(2015) I. R. Minev et al.   SCIENCE

Adaptive rheology and ordering of cell cytoskeleton govern matrix rigidity sensing

(2015) Mukund Gupta et al.   Nature Communications

Directional cell movement through tissues is controlled by exosome secretion

(2015) Bong Hwan Sung et al.   Nature Communications

Mechanics of epithelial closure over non-adherent environments

(2015) Sri Ram Krishna Vedula et al.   Nature Communications

Reinforcement of hydrogels using three-dimensionally printed microfibres

(2015) Jetze Visser et al.   Nature Communications

Orthogonally Engineering Matrix Topography and Rigidity to Regulate Multicellular Morphology

(2014) Benhui Hu et al.   ADVANCED MATERIALS

Spatially Gradated Hydrogel Platform as a 3D Engineered Tumor Microenvironment

(2014) Sara Pedron et al.   ADVANCED MATERIALS

Mesenchymal-Mode Migration Assay and Antimetastatic Drug Screening with High-Throughput Microfluidic Channel Networks

(2014) Yuanqing Zhang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanical Feedback through E-Cadherin Promotes Direction Sensing during Collective Cell Migration

(2014) Danfeng Cai et al.   CELL

Micro-composite substrates for the study of cell-matrix mechanical interactions

(2014) Pen-hsiu Grace Chao et al.   Journal of the Mechanical Behavior of Biomedical Materials

The Nanoscale Geometrical Maturation of Focal Adhesions Controls Stem Cell Differentiation and Mechanotransduction

(2014) Julien E. Gautrot et al.   NANO LETTERS

Extracellular matrix stiffness and composition jointly regulate the induction of malignant phenotypes in mammary epithelium

(2014) Ovijit Chaudhuri et al.   NATURE MATERIALS

Interplay of matrix stiffness and protein tethering in stem cell differentiation

(2014) Jessica H. Wen et al.   NATURE MATERIALS

Physical influences of the extracellular environment on cell migration

(2014) Guillaume Charras et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bio-inspired detoxification using 3D-printed hydrogel nanocomposites

(2014) Maling Gou et al.   Nature Communications

Biochemical and Physical Signal Gradients in Hydrogels to Control Stem Cell Behavior

(2013) Oju Jeon et al.   ADVANCED MATERIALS

Cell-Material Interactions Revealed Via Material Techniques of Surface Patterning

(2013) Xiang Yao et al.   ADVANCED MATERIALS

Integrated Micro/Nanoengineered Functional Biomaterials for Cell Mechanics and Mechanobiology: A Materials Perspective

(2013) Yue Shao et al.   ADVANCED MATERIALS

Cell Durotaxis on Polyelectrolyte Multilayers with Photogenerated Gradients of Modulus

(2013) Jessica S. Martinez et al.   BIOMACROMOLECULES

Nonlinear Strain Stiffening Is Not Sufficient to Explain How Far Cells Can Feel on Fibrous Protein Gels

(2013) Mathilda S. Rudnicki et al.   BIOPHYSICAL JOURNAL

Mesenchymal stem cell durotaxis depends on substrate stiffness gradient strength

(2013) Ludovic G. Vincent et al.   Biotechnology Journal

Substrates with Engineered Step Changes in Rigidity Induce Traction Force Polarity and Durotaxis

(2013) Mark T. Breckenridge et al.   Cellular and Molecular Bioengineering

Nanoparticles Strengthen Intracellular Tension and Retard Cellular Migration

(2013) Chor Yong Tay et al.   NANO LETTERS

3D Printed Bionic Ears

(2013) Manu S. Mannoor et al.   NANO LETTERS

Cadherin-based intercellular adhesions organize epithelial cell-matrix traction forces

(2013) A. F. Mertz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complex Stiffness Gradient Substrates for Studying Mechanotactic Cell Migration

(2012) Cheng-Hwa R. Kuo et al.   ADVANCED MATERIALS

Substrate stiffness regulates cadherin-dependent collective migration through myosin-II contractility

(2012) Mei Rosa Ng et al.   JOURNAL OF CELL BIOLOGY

Fabrication of Hydrogels with Steep Stiffness Gradients for Studying Cell Mechanical Response

(2012) Raimon Sunyer et al.   PLoS One

Topical delivery of siRNA-based spherical nucleic acid nanoparticle conjugates for gene regulation

(2012) Dan Zheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Emerging modes of collective cell migration induced by geometrical constraints

(2012) S. R. K. Vedula et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evidence of a large-scale mechanosensing mechanism for cellular adaptation to substrate stiffness

(2012) L. Trichet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

“Living” Microvascular Stamp for Patterning of Functional Neovessels; Orchestrated Control of Matrix Property and Geometry

(2011) Jae Hyun Jeong et al.   ADVANCED MATERIALS

Disorders of Bone Remodeling

(2011) Xu Feng et al.   Annual Review of Pathology-Mechanisms of Disease

Elasticity boundary conditions required for cell mechanotaxis on microelastically-patterned gels

(2011) Takahito Kawano et al.   BIOMATERIALS

A Mechanoresponsive Cadherin-Keratin Complex Directs Polarized Protrusive Behavior and Collective Cell Migration

(2011) Gregory F. Weber et al.   DEVELOPMENTAL CELL

Nanolithographic Control of the Spatial Organization of Cellular Adhesion Receptors at the Single-Molecule Level

(2011) Mark Schvartzman et al.   NANO LETTERS

Collective cell guidance by cooperative intercellular forces

(2011) Dhananjay T. Tambe et al.   NATURE MATERIALS

Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate

(2011) Justin R. Tse et al.   PLoS One

Collective Cell Migration on Artificial Extracellular Matrix Proteins Containing Full-Length Fibronectin Domains

(2010) Eileen Fong et al.   ADVANCED MATERIALS

Engineering the Extracellular Environment: Strategies for Building 2D and 3D Cellular Structures

(2010) Orane Guillame-Gentil et al.   ADVANCED MATERIALS

Mechanical tugging force regulates the size of cell-cell junctions

(2010) Z. Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Microengineered Platforms for Cell Mechanobiology

(2009) Deok-Ho Kim et al.   Annual Review of Biomedical Engineering

Vascular Smooth Muscle Cell Durotaxis Depends on Substrate Stiffness Gradient Strength

(2009) Brett C. Isenberg et al.   BIOPHYSICAL JOURNAL

Physical forces during collective cell migration

(2009) Xavier Trepat et al.   Nature Physics

Collective cell migration in morphogenesis, regeneration and cancer

(2009) Peter Friedl et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Bio-Inspired, Smart, Multiscale Interfacial Materials

(2008) Fan Xia et al.   ADVANCED MATERIALS

Modular control of endothelial sheet migration

(2008) P. Vitorino et al.   GENES & DEVELOPMENT