Solid stress in brain tumours causes neuronal loss and neurological dysfunction and can be reversed by lithium

A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment

(2018) Amelie Griveau et al.   CANCER CELL

Brain stiffens post mortem

(2018) J. Weickenmeier et al.   Journal of the Mechanical Behavior of Biomedical Materials

Quantifying solid stress and elastic energy from excised or in situ tumors

(2018) Hadi T Nia et al.   Nature Protocols

Acute pressure changes in the brain are correlated with MR elastography stiffness measurements: initial feasibility in an in vivo large animal model

(2017) Arvin Arani et al.   MAGNETIC RESONANCE IN MEDICINE

Nec‐1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice

(2016) Seung‐Hoon Yang et al.   EMBO Molecular Medicine

Dual inhibition of Ang-2 and VEGF receptors normalizes tumor vasculature and prolongs survival in glioblastoma by altering macrophages

(2016) Teresa E. Peterson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ang-2/VEGF bispecific antibody reprograms macrophages and resident microglia to anti-tumor phenotype and prolongs glioblastoma survival

(2016) Jonas Kloepper et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Strain and rate-dependent neuronal injury in a 3D in vitro compression model of traumatic brain injury

(2016) Eyal Bar-Kochba et al.   Scientific Reports

Mechanics of the brain: perspectives, challenges, and opportunities

(2015) Alain Goriely et al.   Biomechanics and Modeling in Mechanobiology

Exploring the Biomechanical Properties of Brain Malignancies and Their Pathologic Determinants In Vivo with Magnetic Resonance Elastography

(2015) Y. Jamin et al.   CANCER RESEARCH

Mechanical properties of gray and white matter brain tissue by indentation

(2015) Silvia Budday et al.   Journal of the Mechanical Behavior of Biomedical Materials

Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment

(2015) Vasileios Askoxylakis et al.   JNCI-Journal of the National Cancer Institute

Blockade of MMP14 Activity in Murine Breast Carcinomas: Implications for Macrophages, Vessels, and Radiotherapy

(2015) Eleanor I. Ager et al.   JNCI-Journal of the National Cancer Institute

A comparison of hyperelastic constitutive models applicable to brain and fat tissues

(2015) L. Angela Mihai et al.   Journal of the Royal Society Interface

Impaired gait pattern as a sensitive tool to assess hypoxic brain damage in a novel mouse model of atherosclerotic plaque rupture

(2015) Lynn Roth et al.   PHYSIOLOGY & BEHAVIOR

Anti-VEGF treatment improves neurological function and augments radiation response in NF2 schwannoma model

(2015) Xing Gao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Generic Support Vector Machine Model for Preoperative Glioma Survival Associations

(2015) Kyrre E. Emblem et al.   RADIOLOGY

Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment

(2015) Vasileios Askoxylakis et al.   JNCI-Journal of the National Cancer Institute

Blockade of MMP14 Activity in Murine Breast Carcinomas: Implications for Macrophages, Vessels, and Radiotherapy

(2015) Eleanor I. Ager et al.   JNCI-Journal of the National Cancer Institute

The Role of Mechanical Forces in Tumor Growth and Therapy

(2014) Rakesh K. Jain et al.   Annual Review of Biomedical Engineering

Compression of Pancreatic Tumor Blood Vessels by Hyaluronan Is Caused by Solid Stress and Not Interstitial Fluid Pressure

(2014) Vikash P. Chauhan et al.   CANCER CELL

Protein Kinase C-δ (PKCδ) Regulates Proinflammatory Chemokine Expression through Cytosolic Interaction with the NF-κB Subunit p65 in Vascular Smooth Muscle Cells

(2014) Jun Ren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The relative value of postoperative versus preoperative Karnofsky Performance Scale scores as a predictor of survival after surgical resection of glioblastoma multiforme

(2014) Lola B. Chambless et al.   JOURNAL OF NEURO-ONCOLOGY

Is the Donnan effect sufficient to explain swelling in brain tissue slices?

(2014) G. E. Lang et al.   Journal of the Royal Society Interface

RIPK3 as a potential therapeutic target for Gaucher's disease

(2014) Einat B Vitner et al.   NATURE MEDICINE

Compression stiffening of brain and its effect on mechanosensing by glioma cells

(2014) Katarzyna Pogoda et al.   NEW JOURNAL OF PHYSICS

White matter changes linked to visual recovery after nerve decompression

(2014) D. A. Paul et al.   Science Translational Medicine

Coevolution of Solid Stress and Interstitial Fluid Pressure in Tumors During Progression: Implications for Vascular Collapse

(2013) Triantafyllos Stylianopoulos et al.   CANCER RESEARCH

Imaging descriptors improve the predictive power of survival models for glioblastoma patients

(2013) M. A. Mazurowski et al.   NEURO-ONCOLOGY

Local mechanical properties of white matter structures in the human brain

(2013) Curtis L. Johnson et al.   NEUROIMAGE

Low Incidence of Pseudoprogression by Imaging in Newly Diagnosed Glioblastoma Patients Treated With Cediranib in Combination With Chemoradiation

(2013) M. C. Pinho et al.   ONCOLOGIST

Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels

(2013) Vikash P. Chauhan et al.   Nature Communications

Software for Computing and Annotating Genomic Ranges

(2013) Michael Lawrence et al.   PLoS Computational Biology

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Assessing Post-Stroke Behavior in Mouse Models of Focal Ischemia

(2012) Mustafa Balkaya et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Lithium enhances remyelination of peripheral nerves

(2012) J. Makoukji et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Causes, consequences, and remedies for growth-induced solid stress in murine and human tumors

(2012) T. Stylianopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Poroelasticity of Cartilage at the Nanoscale

(2011) Hadi Tavakoli Nia et al.   BIOPHYSICAL JOURNAL

Antidepressant-like responses to lithium in genetically diverse mouse strains

(2011) A. Can et al.   GENES BRAIN AND BEHAVIOR

Lithium Ameliorates Neurodegeneration, Suppresses Neuroinflammation, and Improves Behavioral Performance in a Mouse Model of Traumatic Brain Injury

(2011) Fengshan Yu et al.   JOURNAL OF NEUROTRAUMA

Maintenance of primary tumor phenotype and genotype in glioblastoma stem cells

(2011) H. Wakimoto et al.   NEURO-ONCOLOGY

Discrimination between Metastasis and Glioblastoma Multiforme Based on Morphometric Analysis of MR Images

(2010) L. Blanchet et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

A Fully Automated Method for Quantitative Cerebral Hemodynamic Analysis Using DSC–MRI

(2010) Atle Bjørnerud et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Evaluation of Intraoperative Brain Shift Using an Ultrasound-Linked Navigation System for Brain Tumor Surgery

(2010) Shiro OHUE et al.   NEUROLOGIA MEDICO-CHIRURGICA

Valproate Administered after Traumatic Brain Injury Provides Neuroprotection and Improves Cognitive Function in Rats

(2010) Pramod K. Dash et al.   PLoS One

An Automatic Procedure for Normalization of Cerebral Blood Volume Maps in Dynamic Susceptibility Contrast−Based Glioma Imaging

(2009) K.E. Emblem et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

Automatic vessel removal in gliomas from dynamic susceptibility contrast imaging

(2009) Kyrre E. Emblem et al.   MAGNETIC RESONANCE IN MEDICINE

Three-dimensional microscopy of the tumor microenvironment in vivo using optical frequency domain imaging

(2009) Benjamin J Vakoc et al.   NATURE MEDICINE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Increased volume of the amygdala and hippocampus in bipolar patients treated with lithium

(2009) Lara C. Foland et al.   NEUROREPORT

GSK3β Regulates Differentiation and Growth Arrest in Glioblastoma

(2009) Serdar Korur et al.   PLoS One

Brain Lithium Levels and Effects on Cognition and Mood in Geriatric Bipolar Disorder: A Lithium-7 Magnetic Resonance Spectroscopy Study

(2008) Brent P. Forester et al.   AMERICAN JOURNAL OF GERIATRIC PSYCHIATRY

Lithium inhibits invasion of glioma cells; possible involvement of glycogen synthase kinase-3

(2008) Michal O. Nowicki et al.   NEURO-ONCOLOGY