Intranasal Delivery of Genistein-Loaded Nanoparticles as a Potential Preventive System against Neurodegenerative Disorders

Dissociation of chitosan/tripolyphosphate complexes into separate components upon pH elevation

(2018) Petra Mazancová et al.   CARBOHYDRATE POLYMERS

Recent advances in carrier mediated nose-to-brain delivery of pharmaceutics

(2018) Vassilis Bourganis et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs

(2018) Mukta Agrawal et al.   JOURNAL OF CONTROLLED RELEASE

Chitosan Glutamate-Coated Niosomes: A Proposal for Nose-to-Brain Delivery

(2018) Federica Rinaldi et al.   Pharmaceutics

In Situ-Based Gels for Nose to Brain Delivery for the Treatment of Neurological Diseases

(2018) Blessing Aderibigbe   Pharmaceutics

Increasing protective activity of Genistein by loading into transfersomes: a new potential adjuvant in the oxidative stress-related neurodegenerative diseases?

(2018) Rita Langasco et al.   PHYTOMEDICINE

Size optimization and in vitro biocompatibility studies of chitosan nanoparticles

(2017) Gomathi Thandapani et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Targeting Free Radicals in Oxidative Stress-Related Human Diseases

(2017) Patrik Poprac et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Genistein treatment improves fracture resistance in obese diabetic mice

(2017) Britton Odle et al.   BMC Endocrine Disorders

Particulate formulations based on chitosan for nose-to-brain delivery of drugs. A review

(2016) Giovanna Rassu et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Molecular and Therapeutic Targets of Genistein in Alzheimer’s Disease

(2016) Kasi Pandima Devi et al.   MOLECULAR NEUROBIOLOGY

Protective Effect of Genistein against Neuronal Degeneration in ApoE−/− Mice Fed a High-Fat Diet

(2016) Yoon-Jin Park et al.   Nutrients

Nasal chitosan microparticles target a zidovudine prodrug to brain HIV sanctuaries

(2015) Alessandro Dalpiaz et al.   ANTIVIRAL RESEARCH

Bioactivity of genistein: A review of in vitro and in vivo studies

(2015) Ajaz Ahmad Ganai et al.   BIOMEDICINE & PHARMACOTHERAPY

Preparation of chitosan–TPP nanoparticles using microengineered membranes – Effect of parameters and encapsulation of tacrine

(2015) S. Hassani et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Physicochemical and morphological properties of size-controlled chitosan–tripolyphosphate nanoparticles

(2015) John Antoniou et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Propolis as lipid bioactive nano-carrier for topical nasal drug delivery

(2015) Giovanna Rassu et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Solid microparticles based on chitosan or methyl-β-cyclodextrin: A first formulative approach to increase the nose-to-brain transport of deferoxamine mesylate

(2015) Giovanna Rassu et al.   JOURNAL OF CONTROLLED RELEASE

Nose-to-Brain Delivery: Investigation of the Transport of Nanoparticles with Different Surface Characteristics and Sizes in Excised Porcine Olfactory Epithelium

(2015) Alpesh Mistry et al.   MOLECULAR PHARMACEUTICS

Genistein and Cancer: Current Status, Challenges, and Future Directions

(2015) Carmela Spagnuolo et al.   Advances in Nutrition

Impact of Functional Foods on Prevention of Cardiovascular Disease and Diabetes

(2015) Geeta Sikand et al.   Current Cardiology Reports

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

Efficacy of phytoestrogens for menopausal symptoms: a meta-analysis and systematic review

(2014) M-n. Chen et al.   CLIMACTERIC

Nose to brain microemulsion-based drug delivery system of rivastigmine: formulation andex-vivocharacterization

(2014) Brijesh M. Shah et al.   DRUG DELIVERY

Oxidative Stress and Its Significant Roles in Neurodegenerative Diseases and Cancer

(2014) Raynoo Thanan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Chitosan in nasal delivery systems for therapeutic drugs

(2014) Luca Casettari et al.   JOURNAL OF CONTROLLED RELEASE

Nose-to-Brain Delivery: Evaluation of Polymeric Nanoparticles on Olfactory Ensheathing Cells Uptake

(2014) Teresa Musumeci et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Encapsulation and modified-release of thymol from oral microparticles as adjuvant or substitute to current medications

(2014) G. Rassu et al.   PHYTOMEDICINE

Chitosan and cyclodextrin in intranasal microemulsion for improved brain buspirone hydrochloride pharmacokinetics in rats

(2013) Hamza Bshara et al.   CARBOHYDRATE POLYMERS

Direct nose to brain drug deliveryviaintegrated nerve pathways bypassing the blood–brain barrier: an excellent platform for brain targeting

(2013) Chandrakantsing Vijaysing Pardeshi et al.   Expert Opinion on Drug Delivery

Biodegradable Polymeric Nanocapsules Based on Poly(DL-lactide) for Genistein Topical Delivery: Obtention, Characterization and Skin Permeation Studies

(2013) Ana Lúcia Teixeira Carvalho de Zampieri et al.   Journal of Biomedical Nanotechnology

Genistein antagonizes inflammatory damage induced by β-amyloid peptide in microglia through TLR4 and NF-κB

(2013) Xin Zhou et al.   NUTRITION

Stability of Chitosan Nanoparticles Cross-Linked with Tripolyphosphate

(2012) Helene Jonassen et al.   BIOMACROMOLECULES

Bromocriptine loaded chitosan nanoparticles intended for direct nose to brain delivery: Pharmacodynamic, Pharmacokinetic and Scintigraphy study in mice model

(2012) Shadab Md et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Genistein Inhibits Aβ25–35 –Induced Neurotoxicity in PC12 Cells via PKC Signaling Pathway

(2012) Sijing Luo et al.   NEUROCHEMICAL RESEARCH

Formation mechanism of monodisperse, low molecular weight chitosan nanoparticles by ionic gelation technique

(2011) Wen Fan et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Development of solid nanoparticles based on hydroxypropyl-β-cyclodextrin aimed for the colonic transmucosal delivery of diclofenac sodium

(2011) Elisabetta Gavini et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Biocompatible transferrin-conjugated sodium hexametaphosphate-stabilized gold nanoparticles: synthesis, characterization, cytotoxicity and cellular uptake

(2011) Harshala J Parab et al.   NANOTECHNOLOGY

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Tight junction modulation by chitosan nanoparticles: Comparison with chitosan solution

(2010) Driton Vllasaliu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanoparticle-based targeted drug delivery

(2009) Rajesh Singh et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Nanoparticles for direct nose-to-brain delivery of drugs

(2009) Alpesh Mistry et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Natural Antioxidants Protect Neurons in Alzheimer’s Disease and Parkinson’s Disease

(2009) Baolu Zhao   NEUROCHEMICAL RESEARCH

Chitosan/TPP and Chitosan/TPP-hyaluronic Acid Nanoparticles: Systematic Optimisation of the Preparative Process and Preliminary Biological Evaluation

(2009) Alessandro Nasti et al.   PHARMACEUTICAL RESEARCH

Prevention of common neurodegenerative disorders in the elderly

(2008) Laura Fratiglioni et al.   EXPERIMENTAL GERONTOLOGY

Mucoadhesive microspheres for nasal administration of cyclodextrins

(2008) Elisabetta Gavini et al.   JOURNAL OF DRUG TARGETING