Modulation of Hypoxia-Induced Chemoresistance to Polymeric Micellar Cisplatin: The Effect of Ligand Modification of Micellar Carrier Versus Inhibition of the Mediators of Drug Resistance

STAT3 but Not HIF-1α Is Important in Mediating Hypoxia-Induced Chemoresistance in MDA-MB-231, a Triple Negative Breast Cancer Cell Line

(2017) Hoda Soleymani Abyaneh et al.   Cancers

Modulation of Hypoxia in Solid Tumor Microenvironment with MnO2Nanoparticles to Enhance Photodynamic Therapy

(2016) Wenwen Zhu et al.   ADVANCED FUNCTIONAL MATERIALS

Nanoparticles for Targeting Intratumoral Hypoxia: Exploiting a Potential Weakness of Glioblastoma

(2016) Mihaela Aldea et al.   PHARMACEUTICAL RESEARCH

Reprogramming the Transcriptional Response to Hypoxia with a Chromosomally Encoded Cyclic Peptide HIF-1 Inhibitor

(2016) Ishna N. Mistry et al.   ACS Synthetic Biology

Conjugation of pH-responsive nanoparticles to neural stem cells improves intratumoral therapy

(2014) Rachael Mooney et al.   JOURNAL OF CONTROLLED RELEASE

Polymeric micelles for pH-responsive delivery of cisplatin

(2014) Mostafa Shahin et al.   JOURNAL OF DRUG TARGETING

Discovery of P3971 an Orally Efficacious Novel Anticancer Agent Targeting HIF-1α and STAT3 Pathways

(2013) Pallavi Godse et al.   Anti-Cancer Agents in Medicinal Chemistry

A Cyclic Peptide Inhibitor of HIF-1 Heterodimerization That Inhibits Hypoxia Signaling in Cancer Cells

(2013) Elena Miranda et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Hypoxia counteracts taxol-induced apoptosis in MDA-MB-231 breast cancer cells: role of autophagy and JNK activation

(2013) A Notte et al.   Cell Death & Disease

Poly(Adenosine Diphosphate–Ribose) Polymerase Inhibitors in Cancer Treatment

(2012) Sook Ryun Park et al.   HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA

Expression of EGFR Under Tumor Hypoxia: Identification of a Subpopulation of Tumor Cells Responsible for Aggressiveness and Treatment Resistance

(2012) Ilse J. Hoogsteen et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Determination of critical micelle concentration of polybutadiene-block-poly(ethyleneoxide) diblock copolymer by fluorescence spectroscopy and dynamic light scattering

(2012) Önder Topel et al.   JOURNAL OF MOLECULAR LIQUIDS

EGF receptor-targeted nanocarriers for enhanced cancer treatment

(2012) Alyssa M Master et al.   Nanomedicine

Hypoxia-mediated drug resistance: Novel insights on the functional interaction of HIFs and cell death pathways

(2011) Nadine Rohwer et al.   DRUG RESISTANCE UPDATES

Proteolytically Stable Cancer Targeting Peptides with High Affinity for Breast Cancer Cells

(2011) Rania Soudy et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combined treatment targeting HIF-1α and Stat3 is a potent strategy for prostate cancer therapy

(2011) Kavitha Ramasamy Reddy et al.   PROSTATE

Novel self-associating poly(ethylene oxide)-b-poly(ɛ-caprolactone) based drug conjugates and nano-containers for paclitaxel delivery

(2010) Mostafa Shahin et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of EGFR-Targeted Polymer Blend Nanocarriers for Combination Paclitaxel/Lonidamine Delivery To Treat Multi-Drug Resistance in Human Breast and Ovarian Tumor Cells

(2010) Lara Milane et al.   MOLECULAR PHARMACEUTICS

Triple-Negative Breast Cancer

(2010) William D. Foulkes et al.   NEW ENGLAND JOURNAL OF MEDICINE

Preclinical and clinical studies of anticancer agent-incorporating polymer micelles

(2009) Yasuhiro Matsumura et al.   CANCER SCIENCE

Hypoxia induces chemoresistance in ovarian cancer cells by activation of signal transducer and activator of transcription 3

(2009) Karuppaiyah Selvendiran et al.   INTERNATIONAL JOURNAL OF CANCER

Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics

(2009) G L Semenza   ONCOGENE

Targeted Delivery of Gemcitabine to Pancreatic Adenocarcinoma Using Cetuximab as a Targeting Agent

(2008) C. R. Patra et al.   CANCER RESEARCH

In Situ Detection of Live Cancer Cells by Using Bioprobes Based on Au Nanoparticles

(2008) Jaemoon Yang et al.   LANGMUIR

Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity

(2008) R. Sullivan et al.   MOLECULAR CANCER THERAPEUTICS

In vitro and in vivo targeting of hollow gold nanoshells directed at epidermal growth factor receptor for photothermal ablation therapy

(2008) Marites P. Melancon et al.   MOLECULAR CANCER THERAPEUTICS

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Targeted therapies in breast cancer

(2008) Federico Rojo et al.   SEMINARS IN DIAGNOSTIC PATHOLOGY