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Title
NK Cell-Based Immunotherapy in Cancer Metastasis
Authors
Keywords
-
Journal
Cancers
Volume 11, Issue 1, Pages 29
Publisher
MDPI AG
Online
2018-12-29
DOI
10.3390/cancers11010029
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- (2018) Mayumi Hoshikawa et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
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- (2018) Leticía Huergo-Zapico et al. CANCER RESEARCH
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- (2018) Jan P. Böttcher et al. CELL
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- (2018) Xiaoran Liu et al. Chinese Journal of Cancer Research
- Epithelial-mesenchymal transition leads to NK cell–mediated metastasis-specific immunosurveillance in lung cancer
- (2018) Peter J. Chockley et al. JOURNAL OF CLINICAL INVESTIGATION
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- (2018) Qing Zhang et al. NATURE IMMUNOLOGY
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- (2018) Kevin C. Barry et al. NATURE MEDICINE
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- (2018) Lucas Ferrari de Andrade et al. SCIENCE
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- (2018) O. Adotevi et al. OncoImmunology
- Allogenic Natural Killer Cell Immunotherapy Combined with Irreversible Electroporation for Stage IV Hepatocellular Carcinoma: Survival Outcome
- (2018) Mohammed Alnaggar et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Contribution of NK cells to immunotherapy mediated by PD-1/PD-L1 blockade
- (2018) Joy Hsu et al. JOURNAL OF CLINICAL INVESTIGATION
- Short-term clinical efficacy of percutaneous irreversible electroporation combined with allogeneic natural killer cell for treating metastatic pancreatic cancer
- (2017) Mao Lin et al. IMMUNOLOGY LETTERS
- Circulating tumor cell as a biomarker for evaluating allogenic NK cell immunotherapy on stage IV non-small cell lung cancer
- (2017) Mao Lin et al. IMMUNOLOGY LETTERS
- The potential and promise of IL-15 in immuno-oncogenic therapies
- (2017) Tanya O. Robinson et al. IMMUNOLOGY LETTERS
- Dysfunctional Natural Killer Cells in the Aftermath of Cancer Surgery
- (2017) Leonard Angka et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
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- (2017) Y Liu et al. ONCOGENE
- Tumor aneuploidy correlates with markers of immune evasion and with reduced response to immunotherapy
- (2017) Teresa Davoli et al. SCIENCE
- Decreased expression of the NKG2D ligand ULBP4 may be an indicator of poor prognosis in patients with nasopharyngeal carcinoma
- (2017) Yuanji Xu et al. Oncotarget
- Natural killer cell activity for IFN-gamma production as a supportive diagnostic marker for gastric cancer
- (2017) Jongmi Lee et al. Oncotarget
- PD-L1 and epithelial-mesenchymal transition in circulating tumor cells from non-small cell lung cancer patients: A molecular shield to evade immune system?
- (2017) Cristina Raimondi et al. OncoImmunology
- Platelet-mediated shedding of NKG2D ligands impairs NK cell immune-surveillance of tumor cells
- (2017) Stefanie Maurer et al. OncoImmunology
- The immune checkpoint ligand PD-L1 is upregulated in EMT-activated human breast cancer cells by a mechanism involving ZEB-1 and miR-200
- (2017) Muhammad Zaeem Noman et al. OncoImmunology
- Inherent and Tumor-Driven Immune Tolerance in the Prostate Microenvironment Impairs Natural Killer Cell Antitumor Activity
- (2016) Christine Pasero et al. CANCER RESEARCH
- Checkpoint Inhibition of KIR2D with the Monoclonal Antibody IPH2101 Induces Contraction and Hyporesponsiveness of NK Cells in Patients with Myeloma
- (2016) M. Carlsten et al. CLINICAL CANCER RESEARCH
- Metastatic colonization by circulating tumour cells
- (2016) Joan Massagué et al. NATURE
- The tumor microenvironment and Immunoscore are critical determinants of dissemination to distant metastasis
- (2016) Bernhard Mlecnik et al. Science Translational Medicine
- Cytokine-induced memory-like natural killer cells exhibit enhanced responses against myeloid leukemia
- (2016) Rizwan Romee et al. Science Translational Medicine
- Suppression of Metastases Using a New Lymphocyte Checkpoint Target for Cancer Immunotherapy
- (2016) S. J. Blake et al. Cancer Discovery
- Prognostic value of tumor infiltrating NK cells and macrophages in stage II+III esophageal cancer patients
- (2016) Bin Xu et al. Oncotarget
- A combinational therapy of EGFR-CAR NK cells and oncolytic herpes simplex virus 1 for breast cancer brain metastases
- (2016) Xilin Chen et al. Oncotarget
- NK Cells, Tumor Cell Transition, and Tumor Progression in Solid Malignancies: New Hints for NK-Based Immunotherapy?
- (2016) Claudia Cantoni et al. Journal of Immunology Research
- “Natural Regulators”: NK Cells as Modulators of T Cell Immunity
- (2016) Iona S. Schuster et al. Frontiers in Immunology
- Role of IL-2 in cancer immunotherapy
- (2016) Tao Jiang et al. OncoImmunology
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- (2016) Emily M. McWilliams et al. OncoImmunology
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- (2015) M Ricciardi et al. BRITISH JOURNAL OF CANCER
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- (2015) Antonio Pérez-Martínez et al. CYTOTHERAPY
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- (2015) Y.-K. Zhao et al. GENETICS AND MOLECULAR RESEARCH
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- (2015) Zhenxin Wang et al. IMMUNOLOGICAL INVESTIGATIONS
- Increased Tim-3 expression in peripheral NK cells predicts a poorer prognosis and Tim-3 blockade improves NK cell-mediated cytotoxicity in human lung adenocarcinoma
- (2015) Liyun Xu et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Redistribution, Hyperproliferation, Activation of Natural Killer Cells and CD8 T Cells, and Cytokine Production During First-in-Human Clinical Trial of Recombinant Human Interleukin-15 in Patients With Cancer
- (2015) Kevin C. Conlon et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2015) Ana Vuletić et al. PATHOLOGY & ONCOLOGY RESEARCH
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- (2015) Roberto Bellucci et al. OncoImmunology
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- (2015) Jianfeng Han et al. Scientific Reports
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- (2015) Giuseppe Sconocchia et al. NEOPLASIA
- Lymphocyte Subset Recovery and Outcome after Autologous Hematopoietic Stem Cell Transplantation for Plasma Cell Myeloma
- (2014) Jessica Rueff et al. BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION
- Going viral: chimeric antigen receptor T-cell therapy for hematological malignancies
- (2014) Saar Gill et al. IMMUNOLOGICAL REVIEWS
- NKG2D signaling in cancer immunosurveillance
- (2014) Alejandro López-Soto et al. INTERNATIONAL JOURNAL OF CANCER
- MICA/B expression is inhibited by unfolded protein response and associated with poor prognosis in human hepatocellular carcinoma
- (2014) Liang Fang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Cutting Edge: Down-Regulation of MHC Class I-Related Chain A on Tumor Cells by IFN- -Induced MicroRNA
- (2014) D. Yadav et al. JOURNAL OF IMMUNOLOGY
- Cancer-Expanded Myeloid-Derived Suppressor Cells Induce Anergy of NK Cells through Membrane-Bound TGF- 1
- (2014) H. Li et al. JOURNAL OF IMMUNOLOGY
- IL-2: The First Effective Immunotherapy for Human Cancer
- (2014) S. A. Rosenberg JOURNAL OF IMMUNOLOGY
- Enrichment of CD56dimKIR+CD57+ highly cytotoxic NK cells in tumour-infiltrated lymph nodes of melanoma patients
- (2014) Talib Hassan Ali et al. Nature Communications
- Metastasis is regulated via microRNA-200/ZEB1 axis control of tumour cell PD-L1 expression and intratumoral immunosuppression
- (2014) Limo Chen et al. Nature Communications
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- (2014) I. P. da Silva et al. Cancer Immunology Research
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- (2014) Leticia Huergo-Zapico et al. Frontiers in Immunology
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- (2014) Hans Klingemann OncoImmunology
- Mature Cytotoxic CD56bright/CD16+ Natural Killer Cells Can Infiltrate Lymph Nodes Adjacent to Metastatic Melanoma
- (2013) M. Messaoudene et al. CANCER RESEARCH
- Treatment of patients with advanced cancer with the natural killer cell line NK-92
- (2013) Torsten Tonn et al. CYTOTHERAPY
- Shedding of endogenous MHC class I-related chain molecules A and B from different human tumor entities: Heterogeneous involvement of the “a disintegrin and metalloproteases” 10 and 17
- (2013) Guranda Chitadze et al. INTERNATIONAL JOURNAL OF CANCER
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- (2013) Geok Choo Sim et al. JOURNAL OF CLINICAL INVESTIGATION
- Epithelial-Mesenchymal Transition Induces an Antitumor Immune Response Mediated by NKG2D Receptor
- (2013) A. Lopez-Soto et al. JOURNAL OF IMMUNOLOGY
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- (2013) Ana Vuletić et al. JOURNAL OF SURGICAL RESEARCH
- Comprehensive analysis of the percentage of surface receptors and cytotoxic granules positive natural killer cells in patients with pancreatic cancer, gastric cancer, and colorectal cancer
- (2013) Yun-Peng Peng et al. Journal of Translational Medicine
- Regulation of NKG2D signaling during the epithelial-to-mesenchymal transition
- (2013) Alejandro López-Soto et al. OncoImmunology
- Clinico-Pathological Significance of MHC-I Type Chain-associated Protein A Expression in Oral Squamous Cell Carcinoma
- (2012) Jie Wang et al. Asian Pacific Journal of Cancer Prevention
- Expression of ERp5 and GRP78 on the membrane of chronic lymphocytic leukemia cells: association with soluble MICA shedding
- (2012) Leticia Huergo-Zapico et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Melanoma Cells Inhibit NK Cell Functions--Letter
- (2012) G. Sconocchia et al. CANCER RESEARCH
- Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
- (2012) Jaclyn Sceneay et al. CANCER RESEARCH
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- (2012) G. Erdag et al. CANCER RESEARCH
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- (2012) Javier Rodríguez et al. EUROPEAN JOURNAL OF CANCER
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- (2012) Mirna Balsamo et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2012) J. L. Espinoza et al. HAEMATOLOGICA
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- (2012) Teresa M. Petrella et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2012) Jing Ni et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2012) T. Placke et al. JOURNAL OF IMMUNOLOGY
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- (2012) Carmine Stolfi et al. OncoImmunology
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- (2011) T. A. Waldmann et al. BLOOD
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- (2011) M. R. Zocchi et al. BLOOD
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- (2011) A. Heinemann et al. CANCER RESEARCH
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- (2011) T. Placke et al. CANCER RESEARCH
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
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- (2011) M. R. Parkhurst et al. CLINICAL CANCER RESEARCH
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- (2011) N. Halama et al. CLINICAL CANCER RESEARCH
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- (2011) Lorenzo Moretta et al. FEBS LETTERS
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- (2011) Hiroaki Saito et al. Gastric Cancer
- Natural Killer Cells and Solid Tumors
- (2011) Ana Stojanovic et al. Journal of Innate Immunity
- Alternatively spliced NKp30 isoforms affect the prognosis of gastrointestinal stromal tumors
- (2011) Nicolas F Delahaye et al. NATURE MEDICINE
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- (2010) D. M. Benson et al. BLOOD
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- (2010) Diane Seimetz et al. CANCER TREATMENT REVIEWS
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- (2009) F. Romagne et al. BLOOD
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- (2009) C. Menard et al. CANCER RESEARCH
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- (2009) H.-G. Kopp et al. CANCER RESEARCH
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- (2009) A. Paschen et al. CLINICAL CANCER RESEARCH
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- (2009) Philippe O. Gannon et al. JOURNAL OF IMMUNOLOGICAL METHODS
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- (2009) Laurent Boissel et al. LEUKEMIA RESEARCH
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- (2009) A López-Soto et al. ONCOGENE
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- Treatment of Metastatic Melanoma Using Interleukin-2 Alone or in Conjunction with Vaccines
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- (2008) Noam Stern-Ginossar et al. NATURE IMMUNOLOGY
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- (2008) A. Kruschinski et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) M. Jinushi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- NK cell alloreactivity and allogeneic hematopoietic stem cell transplantation
- (2007) Loredana Ruggeri et al. BLOOD CELLS MOLECULES AND DISEASES
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