Discovery of Potential Plant-Derived Peptide Deformylase (PDF) Inhibitors for Multidrug-Resistant Bacteria Using Computational Studies

Exploration for novel inhibitors showing back-to-front approach against VEGFR-2 kinase domain (4AG8) employing molecular docking mechanism and molecular dynamics simulations

(2018) Shailima Rampogu et al.   BMC CANCER

Anti-methicillin-resistance Staphylococcus aureus (MRSA) compounds from Bauhinia kockiana Korth. And their mechanism of antibacterial activity

(2018) Yik Ling Chew et al.   BMC Complementary and Alternative Medicine

The Discovery of Antibacterial Natural Compound Based on Peptide Deformylase

(2018) Li Liang et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

The multi-faceted potential of plant-derived metabolites as antimicrobial agents against multidrug-resistant pathogens

(2018) Jonghoon Shin et al.   MICROBIAL PATHOGENESIS

Phytochemical standardization and biological activities of certain desert plants growing in Saudi Arabia

(2018) Muneera S. Al-Saleem et al.   SAUDI PHARMACEUTICAL JOURNAL

Ginger (Zingiber officinale) phytochemicals—gingerenone-A and shogaol inhibit SaHPPK: molecular docking, molecular dynamics simulations and in vitro approaches

(2018) Shailima Rampogu et al.   Annals of Clinical Microbiology and Antimicrobials

Understanding the Effectiveness of Natural Compound Mixtures in Cancer through Their Molecular Mode of Action

(2017) Thazin Aung et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sulfonanilide Derivatives in Identifying Novel Aromatase Inhibitors by Applying Docking, Virtual Screening, and MD Simulations Studies

(2017) Shailima Rampogu et al.   Biomed Research International

Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens

(2017) Ramesh Subramani et al.   3 Biotech

Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens

(2017) Ramesh Subramani et al.   3 Biotech

New peptide deformylase inhibitors design, synthesis and pharmacokinetic assessment

(2016) Fengping Lv et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Multidrug-Resistant Bacteria in the Community

(2016) David van Duin et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

New Perspectives on the Use of Phytochemicals as an Emergent Strategy to Control Bacterial Infections Including Biofilms

(2016) Anabela Borges et al.   MOLECULES

Dietary Natural Products for Prevention and Treatment of Liver Cancer

(2016) Yue Zhou et al.   Nutrients

A unique peptide deformylase platform to rationally design and challenge novel active compounds

(2016) Sonia Fieulaine et al.   Scientific Reports

Public Databases of Plant Natural Products for Computational Drug Discovery

(2015) Chun-Wei Tung   Current Computer-Aided Drug Design

Phytochemical screening and antimicrobial activity of some medicinal plants against multi-drug resistant bacteria from clinical isolates

(2014) Sharmishtha Purkayastha et al.   INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES

TIPdb-3D: the three-dimensional structure database of phytochemicals from Taiwan indigenous plants

(2014) C.-W. Tung et al.   Database-The Journal of Biological Databases and Curation

Combating Pathogenic Microorganisms Using Plant-Derived Antimicrobials: A Minireview of the Mechanistic Basis

(2014) Abhinav Upadhyay et al.   Biomed Research International

TIPdb: A Database of Anticancer, Antiplatelet, and Antituberculosis Phytochemicals from Indigenous Plants in Taiwan

(2013) Ying-Chi Lin et al.   TheScientificWorldJOURNAL

Structures ofStaphylococcus aureuspeptide deformylase in complex with two classes of new inhibitors

(2012) Sang Jae Lee et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Plant-derived antimicrobial compounds: alternatives to antibiotics

(2012) Dianella Savoia   Future Microbiology

New peptide deformylase inhibitors and cooperative interaction: a combination to improve antibacterial activity

(2012) Emilie Goemaere et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

(2012) A. Zorzet et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Prediction of the binding modes between macrolactin N and peptide deformylase from Staphylococcus aureus by molecular docking and molecular dynamics simulations

(2012) Jian Gao et al.   MEDICINAL CHEMISTRY RESEARCH

Combating Antimicrobial Resistance: Policy Recommendations to Save Lives

(2011)   CLINICAL INFECTIOUS DISEASES

Iminosugars as therapeutic agents: recent advances and promising trends

(2011) Robert J Nash et al.   Future Medicinal Chemistry

Jacaranda cuspidifolia Mart. (Bignoniaceae) as an Antibacterial Agent

(2011) Ana Lúcia A. Arruda et al.   JOURNAL OF MEDICINAL FOOD

Insights from ligand and structure based methods in virtual screening of selective Ni-peptide deformylase inhibitors

(2011) Ravi Shekar Ananthula et al.   JOURNAL OF MOLECULAR MODELING

Structure-Activity Relationship Analysis of the Peptide Deformylase Inhibitor 5-Bromo-1H-indole-3-acetohydroxamic Acid

(2008) Sylvain Petit et al.   ChemMedChem