Compensatory mutations in agrC partly restore fitness in vitro to peptide deformylase inhibitor-resistant Staphylococcus aureus

Impact of Granulocytes on the Antimicrobial Effect of Tedizolid in a Mouse Thigh Infection Model

(2011) G. L. Drusano et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Pharmacokinetics and Unexpected Safety Issues of LBM415, a Novel Oral Peptide Deformylase Inhibitor

(2011) P Rolan et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Determination of Disk Diffusion and MIC Quality Control Ranges for GSK1322322, a Novel Peptide Deformylase Inhibitor

(2011) James E. Ross et al.   JOURNAL OF CLINICAL MICROBIOLOGY

Activation of initiation factor 2 by ligands and mutations for rapid docking of ribosomal subunits

(2010) Michael Y Pavlov et al.   EMBO JOURNAL

Formyl peptide receptor-mediated proinflammatory consequences of peptide deformylase inhibition in Staphylococcus aureus

(2010) Diana Mader et al.   MICROBES AND INFECTION

Error-prone initiation factor 2 mutations reduce the fitness cost of antibiotic resistance

(2010) Anna Zorzet et al.   MOLECULAR MICROBIOLOGY

Gene Amplification and Adaptive Evolution in Bacteria

(2009) Dan I. Andersson et al.   Annual Review of Genetics

In Vivo Characterization of the Peptide Deformylase Inhibitor LBM415 in Murine Infection Models

(2009) C. S. Osborne et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Mutations in Three Distinct Loci Cause Resistance to Peptide Deformylase Inhibitors in Bacillus subtilis

(2009) Y. Duroc et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Nitrofurantoin resistance mechanism and fitness cost in Escherichia coli

(2008) L. Sandegren et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Differential Recognition of Staphylococcus aureus Quorum-Sensing Signals Depends on Both Extracellular Loops 1 and 2 of the Transmembrane Sensor AgrC

(2008) Rasmus O. Jensen et al.   JOURNAL OF MOLECULAR BIOLOGY