A Systematic Review, Meta-Analysis, and Meta-Regression Evaluating the Efficacy and Mechanisms of Action of Probiotics and Synbiotics in the Prevention of Surgical Site Infections and Surgery-Related Complications

Effects of perioperative supplementation with pro-/synbiotics on clinical outcomes in surgical patients: A meta-analysis with trial sequential analysis of randomized controlled trials

(2018) Xiang-Dong Wu et al.   CLINICAL NUTRITION

Efficacy of prophylactic probiotics in combination with antibiotics versus antibiotics alone for colorectal surgery: A meta-analysis of randomized controlled trials

(2018) Xiang-Dong Wu et al.   JOURNAL OF SURGICAL ONCOLOGY

Surgical site infection after gastrointestinal surgery in high-income, middle-income, and low-income countries: a prospective, international, multicentre cohort study

(2018) Aneel Bhangu et al.   LANCET INFECTIOUS DISEASES

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

The role of the gut microbiome in systemic inflammatory disease

(2018) Jose C Clemente et al.   BMJ-British Medical Journal

Post-Antibiotic Gut Mucosal Microbiome Reconstitution Is Impaired by Probiotics and Improved by Autologous FMT

(2018) Jotham Suez et al.   CELL

Implication of gut microbiota metabolites in cardiovascular and metabolic diseases

(2018) Francois Brial et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The Potential of Gut Commensals in Reinforcing Intestinal Barrier Function and Alleviating Inflammation

(2018) Kaisa Hiippala et al.   Nutrients

Novel insight into the role of microbiota in colorectal surgery

(2017) Radu Bachmann et al.   GUT

American College of Surgeons and Surgical Infection Society: Surgical Site Infection Guidelines, 2016 Update

(2017) Kristen A. Ban et al.   JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS

Gut microbiota and bacterial translocation in digestive surgery: the impact of probiotics

(2017) Shunichiro Komatsu et al.   LANGENBECKS ARCHIVES OF SURGERY

Bacteroidales recruit IL-6-producing intraepithelial lymphocytes in the colon to promote barrier integrity

(2017) K A Kuhn et al.   Mucosal Immunology

Postoperative changes of the microbiome: are surgical complications related to the gut flora? A systematic review

(2017) Ann-Kathrin Lederer et al.   BMC Surgery

Impact of Probiotic Administration on Serum C-Reactive Protein Concentrations: Systematic Review and Meta-Analysis of Randomized Control Trials

(2017) Mohsen Mazidi et al.   Nutrients

From clinical uncertainties to precision medicine: the emerging role of the gut barrier and microbiome in small bowel functional diseases

(2017) Wojciech Marlicz et al.   Expert Review of Gastroenterology & Hepatology

Centers for Disease Control and Prevention Guideline for the Prevention of Surgical Site Infection, 2017

(2017) Sandra I. Berríos-Torres et al.   JAMA Surgery

Randomised clinical trial: the effects of a multispecies probiotic vs. placebo on innate immune function, bacterial translocation and gut permeability in patients with cirrhosis

(2016) A. Horvath et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Probiotics and Synbiotics Decrease Postoperative Sepsis in Elective Gastrointestinal Surgical Patients: a Meta-Analysis

(2016) Sudha Arumugam et al.   JOURNAL OF GASTROINTESTINAL SURGERY

Probiotics and synbiotics for the prevention of postoperative infections following abdominal surgery: a systematic review and meta-analysis of randomized controlled trials

(2016) L. Lytvyn et al.   JOURNAL OF HOSPITAL INFECTION

Effect of Perioperative Probiotics and Synbiotics on Postoperative Infections After Gastrointestinal Surgery: A Systematic Review With Meta-Analysis

(2016) Zhiping Yang et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Diet–microbiota interactions as moderators of human metabolism

(2016) Justin L. Sonnenburg et al.   NATURE

The gut microbiota and gastrointestinal surgery

(2016) Kristina Guyton et al.   Nature Reviews Gastroenterology & Hepatology

The Human Intestinal Microbiome in Health and Disease

(2016) Susan V. Lynch et al.   NEW ENGLAND JOURNAL OF MEDICINE

The effect of perioperative probiotics treatment for colorectal cancer: short-term outcomes of a randomized controlled trial

(2016) Yongzhi Yang et al.   Oncotarget

Hospital and Payer Costs Associated With Surgical Complications

(2016) Mark A. Healy et al.   JAMA Surgery

Metabolomic fingerprint of severe obesity is dynamically affected by bariatric surgery in a procedure-dependent manner

(2015) Ewa Gralka et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Combined Mechanical and Oral Antibiotic Bowel Preparation Reduces Incisional Surgical Site Infection and Anastomotic Leak Rates After Elective Colorectal Resection

(2015) John E. Scarborough et al.   ANNALS OF SURGERY

Synbiotics in Surgery for Chronic Pancreatitis

(2015) Ashwin Rammohan et al.   ANNALS OF SURGERY

Positive regulatory effects of perioperative probiotic treatment on postoperative liver complications after colorectal liver metastases surgery: a double-center and double-blind randomized clinical trial

(2015) Zhihua Liu et al.   BMC GASTROENTEROLOGY

Gut microbiota and environment in patients with major burns – A preliminary report

(2015) Kentaro Shimizu et al.   BURNS

Crosstalk between Microbiota-Derived Short-Chain Fatty Acids and Intestinal Epithelial HIF Augments Tissue Barrier Function

(2015) Caleb J. Kelly et al.   Cell Host & Microbe

Patients Receiving Prebiotics and Probiotics Before Liver Transplantation Develop Fewer Infections Than Controls: A Systematic Review and Meta-Analysis

(2015) Tarek Sawas et al.   Clinical Gastroenterology and Hepatology

Metabolites of Dietary Protein and Peptides by Intestinal Microbes and their Impacts on Gut

(2015) Peixin Fan et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Metagenomic Analysis Reveals Dynamic Changes of Whole Gut Microbiota in the Acute Phase of Intensive Care Unit Patients

(2015) Masahiro Ojima et al.   DIGESTIVE DISEASES AND SCIENCES

Hospital Cost-Analysis of Complications after Major Abdominal Surgery

(2015) Jennifer Straatman et al.   DIGESTIVE SURGERY

Antibiotics promote inflammation through the translocation of native commensal colonic bacteria

(2015) Kathryn A Knoop et al.   GUT

Perioperative Synbiotics Decrease Postoperative Complications in Periampullary Neoplasms: A Randomized, Double-Blind Clinical Trial

(2015) Heloisa Martins Sommacal et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

A gut-vascular barrier controls the systemic dissemination of bacteria

(2015) Ilaria Spadoni et al.   SCIENCE

Efficacy of perioperative synbiotics treatment for the prevention of surgical site infection after laparoscopic colorectal surgery: a randomized controlled trial

(2015) Shunichiro Komatsu et al.   SURGERY TODAY

A Four-Probiotics Regimen Reduces Postoperative Complications After Colorectal Surgery: A Randomized, Double-Blind, Placebo-Controlled Study

(2015) Katerina Kotzampassi et al.   WORLD JOURNAL OF SURGERY

Impact of perioperative probiotic treatment for surgical site infections in patients with colorectal cancer

(2015) NAOYA AISU et al.   Experimental and Therapeutic Medicine

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

(2015) L. Shamseer et al.   BMJ-British Medical Journal

Preferred reporting items for systematic review and meta-analysis protocols (PRISMA-P) 2015: elaboration and explanation

(2015) L. Shamseer et al.   BMJ-British Medical Journal

Burn Injury Alters the Intestinal Microbiome and Increases Gut Permeability and Bacterial Translocation

(2015) Zachary M. Earley et al.   PLoS One

Randomized clinical trial of the effect of perioperative synbioticsversusno synbiotics on bacterial translocation after oesophagectomy

(2014) Y. Yokoyama et al.   BRITISH JOURNAL OF SURGERY

Role of the Intestinal Microbiota in Resistance to Colonization by Clostridium difficile

(2014) Robert A. Britton et al.   GASTROENTEROLOGY

IL-6 Stimulates Intestinal Epithelial Proliferation and Repair after Injury

(2014) Kristine A. Kuhn et al.   PLoS One

Comparison between oral antibiotics and probiotics as bowel preparation for elective colon cancer surgery to prevent infection: Prospective randomized trial

(2014) Sotaro Sadahiro et al.   SURGERY

Membership and Behavior of Ultra-Low-Diversity Pathogen Communities Present in the Gut of Humans during Prolonged Critical Illness

(2014) A. Zaborin et al.   mBio

Host lifestyle affects human microbiota on daily timescales

(2014) Lawrence A David et al.   GENOME BIOLOGY

The Preventive Surgical Site Infection Bundle in Colorectal Surgery

(2014) Jeffrey E. Keenan et al.   JAMA Surgery

The Detection of Intraoperative Bacterial Translocation in the Mesenteric Lymph Nodes Is Useful in Predicting Patients at High Risk for Postoperative Infectious Complications After Esophagectomy

(2013) Eiji Nishigaki et al.   ANNALS OF SURGERY

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

(2013) Yukihiro Furusawa et al.   NATURE

Perioperative synbiotic therapy in elderly patients undergoing gastroenterological surgery: A prospective, randomized control trial

(2013) Mitsuyoshi Okazaki et al.   NUTRITION

The effects of perioperative probiotic treatment on serum zonulin concentration and subsequent postoperative infectious complications after colorectal cancer surgery: a double-center and double-blind randomized clinical trial

(2012) Zhi-Hua Liu et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Lactobacillus plantarum 299v Does Not Reduce Enteric Bacteria or Bacterial Translocation in Patients Undergoing Colon Resection

(2012) Peter Mangell et al.   DIGESTIVE DISEASES AND SCIENCES

Intestinal Tissues Induce an SNP Mutation in Pseudomonas aeruginosa That Enhances Its Virulence: Possible Role in Anastomotic Leak

(2012) Andrea D. Olivas et al.   PLoS One

Temporal Variations of the Ileal Microbiota in Intestinal Ischemia and Reperfusion

(2012) Fan Wang et al.   SHOCK

Impact of perioperative administration of synbiotics in patients with esophageal cancer undergoing esophagectomy: A prospective randomized controlled trial

(2012) Koji Tanaka et al.   SURGERY

Effect of pre- and probiotics on liver regeneration after resection: a randomised, double-blind pilot study

(2012) N. Rayes et al.   Beneficial Microbes

Preoperative Probiotics Decrease Postoperative Infectious Complications of Colorectal Cancer

(2011) Ji-Wei Zhang et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Dramatic Changes of the Gut Flora Immediately After Severe and Sudden Insults

(2011) Mineji Hayakawa et al.   DIGESTIVE DISEASES AND SCIENCES

Effects of Perioperative Synbiotic Treatment on Infectious Complications, Intestinal Integrity, and Fecal Flora and Organic Acids in Hepatic Surgery With or Without Cirrhosis

(2011) Makoto Usami et al.   JOURNAL OF PARENTERAL AND ENTERAL NUTRITION

Bifidobacteria can protect from enteropathogenic infection through production of acetate

(2011) Shinji Fukuda et al.   NATURE

Potential beneficial effects of butyrate in intestinal and extraintestinal diseases

(2011) Roberto Berni Canani   WORLD JOURNAL OF GASTROENTEROLOGY

Randomised clinical trial: the effects of perioperative probiotic treatment on barrier function and post-operative infectious complications in colorectal cancer surgery - a double-blind study

(2010) Z. Liu et al.   ALIMENTARY PHARMACOLOGY & THERAPEUTICS

Perioperative synbiotic treatment to prevent infectious complications in patients after elective living donor liver transplantation: a prospective randomized study

(2010) Susumu Eguchi et al.   AMERICAN JOURNAL OF SURGERY

Rectal Cancer Surgery With or Without Bowel Preparation

(2010) Frederic Bretagnol et al.   ANNALS OF SURGERY

Intraoperative Bacterial Translocation Detected by Bacterium-Specific Ribosomal RNA-Targeted Reverse-Transcriptase Polymerase Chain Reaction for the Mesenteric Lymph Node Strongly Predicts Postoperative Infectious Complications After Major Hepatectomy for Biliary Malignancies

(2010) Takashi Mizuno et al.   ANNALS OF SURGERY

Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms

(2010) Sa'ad H. Al-Lahham et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Clinical significance of serum diamine oxidase activity in inflammatory bowel disease

(2010) Yusuke Honzawa et al.   INFLAMMATORY BOWEL DISEASES

Influence of Prophylactic Probiotics and Selective Decontamination on Bacterial Translocation in Patients Undergoing Pancreatic Surgery

(2010) Gwendolyn M. P. Diepenhorst et al.   SHOCK

The molecular Koch's postulates and surgical infection: A view forward

(2010) John B. Seal et al.   SURGERY

Preoperative synbiotic bowel conditioning for elective colorectal surgery

(2010) Matjaž Horvat et al.   WIENER KLINISCHE WOCHENSCHRIFT

Post-discharge surveillance to identify colorectal surgical site infection rates and related costs

(2009) J. Tanner et al.   JOURNAL OF HOSPITAL INFECTION

Human gut microbiome adopts an alternative state following small bowel transplantation

(2009) A. L. Hartman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C-reactive protein: a predictive factor and marker of inflammation in inflammatory bowel disease. Results from a prospective population-based study

(2008) M Henriksen et al.   GUT