A Red Light Activatable Multifunctional Prodrug for Image-Guided Photodynamic Therapy and Cascaded Chemotherapy

Smart and hyper-fast responsive polyprodrug nanoplatform for targeted cancer therapy

(2016) Xiao-Ding Xu et al.   BIOMATERIALS

Dual-Stage-Light-Guided Tumor Inhibition by Mitochondria-Targeted Photodynamic Therapy

(2015) Kai Han et al.   ADVANCED FUNCTIONAL MATERIALS

A Dual-FRET-Based Versatile Prodrug for Real-Time Drug Release Monitoring and In Situ Therapeutic Efficacy Evaluation

(2015) Shi-Ying Li et al.   ADVANCED FUNCTIONAL MATERIALS

In Situ Formation of Nanofibers from Purpurin18-Peptide Conjugates and the Assembly Induced Retention Effect in Tumor Sites

(2015) Di Zhang et al.   ADVANCED MATERIALS

Current advances in lanthanide ion (Ln3+)-based upconversion nanomaterials for drug delivery

(2015) Dongmei Yang et al.   CHEMICAL SOCIETY REVIEWS

Stimuli-responsive PEGylated prodrugs for targeted doxorubicin delivery

(2015) Minghui Xu et al.   Materials Science & Engineering C-Materials for Biological Applications

Multifunctional Theranostic Nanoplatform for Cancer Combined Therapy Based on Gold Nanorods

(2015) Wei-Hai Chen et al.   Advanced Healthcare Materials

Tunable Temperature-Responsive Supramolecular Hydrogels Formed by Prodrugs As a Codelivery System

(2014) Wei Ha et al.   ACS Applied Materials & Interfaces

Conjugated-Polyelectrolyte-Based Polyprodrug: Targeted and Image-Guided Photodynamic and Chemotherapy with On-Demand Drug Release upon Irradiation with a Single Light Source

(2014) Youyong Yuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A porous tissue engineering scaffold selectively degraded by cell-generated reactive oxygen species

(2014) John R. Martin et al.   BIOMATERIALS

A pH-responsive prodrug for real-time drug release monitoring and targeted cancer therapy

(2014) Shi-Ying Li et al.   CHEMICAL COMMUNICATIONS

Far-Red Light Activatable, Multifunctional Prodrug for Fluorescence Optical Imaging and Combinational Treatment

(2014) Moses Bio et al.   JOURNAL OF MEDICINAL CHEMISTRY

Development and Bioorthogonal Activation of Palladium-Labile Prodrugs of Gemcitabine

(2014) Jason T. Weiss et al.   JOURNAL OF MEDICINAL CHEMISTRY

Combination of Small Molecule Prodrug and Nanodrug Delivery: Amphiphilic Drug–Drug Conjugate for Cancer Therapy

(2014) Ping Huang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Near-Infrared Photoregulated Drug Release in Living Tumor Tissue via Yolk-Shell Upconversion Nanocages

(2013) Lingzhi Zhao et al.   ADVANCED FUNCTIONAL MATERIALS

Tumor Redox Heterogeneity-Responsive Prodrug Nanocapsules for Cancer Chemotherapy

(2013) Jinqiang Wang et al.   ADVANCED MATERIALS

Near-Infrared Light-Mediated Photoactivation of a Platinum Antitumor Prodrug and Simultaneous Cellular Apoptosis Imaging by Upconversion-Luminescent Nanoparticles

(2013) Yuanzeng Min et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Reactive Oxygen Species (ROS)-Responsive Polymer for Safe, Efficient, and Targeted Gene Delivery in Cancer Cells

(2013) Min Suk Shim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and Cytostatic Evaluation of 4-N-Alkanoyl and 4-N-Alkyl Gemcitabine Analogues

(2013) Jesse Pulido et al.   JOURNAL OF MEDICINAL CHEMISTRY

Folate-Based Near-Infrared Fluorescent Theranostic Gemcitabine Delivery

(2013) Zhigang Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Gemcitabine–Coumarin–Biotin Conjugates: A Target Specific Theranostic Anticancer Prodrug

(2013) Sukhendu Maiti et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Vivo Multimodality Imaging and Cancer Therapy by Near-Infrared Light-Triggered trans-Platinum Pro-Drug-Conjugated Upconverison Nanoparticles

(2013) Yunlu Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photo-Triggered Release of Caged Camptothecin Prodrugs from Dually Responsive Shell Cross-Linked Micelles

(2013) Xianglong Hu et al.   MACROMOLECULES

Stimuli-responsive nanocarriers for drug delivery

(2013) Simona Mura et al.   NATURE MATERIALS

Bioinspired phospholipid polymer prodrug as a pH-responsive drug delivery system for cancer therapy

(2013) Haibo Wang et al.   Polymer Chemistry

Encapsulation of an Adamantane-Doxorubicin Prodrug in pH-Responsive Polysaccharide Capsules for Controlled Release

(2012) Guo-Feng Luo et al.   ACS Applied Materials & Interfaces

Gemcitabine versus Modified Gemcitabine: A Review of Several Promising Chemical Modifications

(2012) Elodie Moysan et al.   MOLECULAR PHARMACEUTICS

Visible Light Controlled Release of Anticancer Drug through Double Activation of Prodrug

(2012) Abugafar M. L. Hossion et al.   ACS Medicinal Chemistry Letters

Long circulation and cytotoxicity of PEGylated gemcitabine and its potential for the treatment of pancreatic cancer

(2010) Mallaredy Vandana et al.   BIOMATERIALS

Porphyrin-functionalized amphiphilic diblock copolypeptides for photodynamic therapy

(2010) Ze-Yong Li et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

(2010) D. Scott Wilson et al.   NATURE MATERIALS

A Novel Doxorubicin Prodrug with Controllable Photolysis Activation for Cancer Chemotherapy

(2010) Stuart Ibsen et al.   PHARMACEUTICAL RESEARCH

Development of enzymatically cleavable prodrugs derived from dendritic polyglycerol

(2009) Marcelo Calderón et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Intracellular imaging of HeLa cells by non-functionalized NaYF4 : Er3+, Yb3+upconverting nanoparticles

(2009) Fiorenzo Vetrone et al.   Nanoscale

Antitumoral activity of PEG–gemcitabine prodrugs targeted by folic acid

(2008) Gianfranco Pasut et al.   JOURNAL OF CONTROLLED RELEASE

Prodrugs: design and clinical applications

(2008) Jarkko Rautio et al.   NATURE REVIEWS DRUG DISCOVERY