A reproducible scaffold-free 3D organoid model to study neoplastic progression in breast cancer

A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity

(2018) Norman Sachs et al.   CELL

Cell diversity and network dynamics in photosensitive human brain organoids

(2017) Giorgia Quadrato et al.   NATURE

Single-cell RNA-seq enables comprehensive tumour and immune cell profiling in primary breast cancer

(2017) Woosung Chung et al.   Nature Communications

Mesenchymal Stem Cell-Induced DDR2 Mediates Stromal-Breast Cancer Interactions and Metastasis Growth

(2017) Maria E. Gonzalez et al.   Cell Reports

Dispersible oxygen microsensors map oxygen gradients in three-dimensional cell cultures

(2017) Sasha Cai Lesher-Pérez et al.   Biomaterials Science

Role of tumor microenvironment in tumorigenesis

(2017) Maonan Wang et al.   Journal of Cancer

Organoids: A historical perspective of thinking in three dimensions

(2016) Marina Simian et al.   JOURNAL OF CELL BIOLOGY

MMTV-cre;Ccn6 knockout mice develop tumors recapitulating human metaplastic breast carcinomas

(2016) E E Martin et al.   ONCOGENE

3D tumor spheroid models for in vitro therapeutic screening: a systematic approach to enhance the biological relevance of data obtained

(2016) Michele Zanoni et al.   Scientific Reports

Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients

(2015) Marc van de Wetering et al.   CELL

Quantification of regenerative potential in primary human mammary epithelial cells

(2015) J. R. Linnemann et al.   DEVELOPMENT

A strategy for tissue self-organization that is robust to cellular heterogeneity and plasticity

(2015) Alec E. Cerchiari et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Metastatic breast cancer cells in lymph nodes increase nodal collagen density

(2015) Asif Rizwan et al.   Scientific Reports

Media additives to promote spheroid circularity and compactness in hanging drop platform

(2015) Brendan M. Leung et al.   Biomaterials Science

The Acinar Cage: Basement Membranes Determine Molecule Exchange and Mechanical Stability of Human Breast Cell Acini

(2015) Aljona Gaiko-Shcherbak et al.   PLoS One

CCN6 Knockdown Disrupts Acinar Organization of Breast Cells in Three-dimensional Cultures through Up-regulation of Type III TGF-β Receptor

(2015) Anupama Pal et al.   NEOPLASIA

3D cell culture systems modeling tumor growth determinants in cancer target discovery

(2014) Claudio R. Thoma et al.   ADVANCED DRUG DELIVERY REVIEWS

Multicellular Architecture of Malignant Breast Epithelia Influences Mechanics

(2014) Gautham Venugopalan et al.   PLoS One

Three Dimensional Cultures: A Tool To Study Normal Acinar Architecture vs. Malignant Transformation Of Breast Cells

(2014) Anupama Pal et al.   Jove-Journal of Visualized Experiments

Multiparameter analyses of three-dimensionally cultured tumor spheroids based on respiratory activity and comprehensive gene expression profiles

(2013) Yuanshu Zhou et al.   ANALYTICAL BIOCHEMISTRY

Tissue-based identification of stem cells and epithelial-to-mesenchymal transition in breast cancer

(2013) Talha E. Anwar et al.   HUMAN PATHOLOGY

Increased extracellular matrix density decreases MCF10A breast cell acinus formation in 3D culture conditions

(2013) Amanda Lance et al.   Journal of Tissue Engineering and Regenerative Medicine

Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation

(2012) Maria Vinci et al.   BMC BIOLOGY

Self-Formation of Optic Cups and Storable Stratified Neural Retina from Human ESCs

(2012) Tokushige Nakano et al.   Cell Stem Cell

Towards definition of an ECM parts list: An advance on GO categories

(2012) Alexandra Naba et al.   MATRIX BIOLOGY

Hypoxic Conditions Induce a Cancer-Like Phenotype in Human Breast Epithelial Cells

(2012) Marica Vaapil et al.   PLoS One

Development of a three-dimensional microfluidic system for long-term tumor spheroid culture

(2012) Karina Ziółkowska et al.   SENSORS AND ACTUATORS B-CHEMICAL

Stiffness of photocrosslinked RGD-alginate gels regulates adipose progenitor cell behavior

(2011) Emily M. Chandler et al.   BIOTECHNOLOGY AND BIOENGINEERING

Long-term Expansion of Epithelial Organoids From Human Colon, Adenoma, Adenocarcinoma, and Barrett's Epithelium

(2011) Toshiro Sato et al.   GASTROENTEROLOGY

Temporal and Spatial Cooperation of Snail1 and Twist1 during Epithelial-Mesenchymal Transition Predicts for Human Breast Cancer Recurrence

(2011) D. D. Tran et al.   MOLECULAR CANCER RESEARCH

Spheroid Assay to Measure TGF-β-induced Invasion

(2011) Hildegonda P.H. Naber et al.   Jove-Journal of Visualized Experiments

Induction and Testing of Hypoxia in Cell Culture

(2011) Danli Wu et al.   Jove-Journal of Visualized Experiments

High-throughput 3D spheroid culture and drug testing using a 384 hanging drop array

(2010) Yi-Chung Tung et al.   ANALYST

The GOX/CAT system: A novel enzymatic method to independently control hydrogen peroxide and hypoxia in cell culture

(2009) S Mueller et al.   Advances in Medical Sciences

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL