Extended access to nicotine leads to a CRF1receptor dependent increase in anxiety-like behavior and hyperalgesia in rats

Robust Escalation of Nicotine Intake with Extended Access to Nicotine Self-Administration and Intermittent Periods of Abstinence

(2012) Ami Cohen et al.   NEUROPSYCHOPHARMACOLOGY

Reward, Addiction, Withdrawal to Nicotine

(2011) Mariella De Biasi et al.   Annual Review of Neuroscience

Nicotine self-administration and reinstatement of nicotine-seeking in male and female rats

(2011) Matthew W. Feltenstein et al.   DRUG AND ALCOHOL DEPENDENCE

Blockade of CRF1 receptors in the central nucleus of the amygdala attenuates the dysphoria associated with nicotine withdrawal in rats

(2011) Adrie W. Bruijnzeel et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

A lack of association between severity of nicotine withdrawal and individual differences in compensatory nicotine self-administration in rats

(2011) Andrew C. Harris et al.   PSYCHOPHARMACOLOGY

Early Emerging Nicotine-Dependence Symptoms: A Signal of Propensity for Chronic Smoking Behavior in Adolescents

(2010) Lisa Dierker et al.   JOURNAL OF PEDIATRICS

Pain is a salient “stressor” that is mediated by corticotropin-releasing factor-1 receptors

(2010) Michele Hummel et al.   NEUROPHARMACOLOGY

Early Course of Nicotine Dependence in Adolescent Smokers

(2010) C. A. Doubeni et al.   PEDIATRICS

Corticotropin-Releasing Factor-1 Receptor Activation Mediates Nicotine Withdrawal-Induced Deficit in Brain Reward Function and Stress-Induced Relapse

(2009) Adrie W. Bruijnzeel et al.   BIOLOGICAL PSYCHIATRY

Role of CRF and other neuropeptides in stress-induced reinstatement of drug seeking

(2009) Uri Shalev et al.   BRAIN RESEARCH

The Role of  6-Containing Nicotinic Acetylcholine Receptors in Nicotine Reward and Withdrawal

(2009) K. J. Jackson et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Corticotropin-Releasing Factor Within the Central Nucleus of the Amygdala and the Nucleus Accumbens Shell Mediates the Negative Affective State of Nicotine Withdrawal in Rats

(2009) Catherine A Marcinkiewcz et al.   NEUROPSYCHOPHARMACOLOGY

Decreased reinforcing effects of cocaine following 2 weeks of continuous d-amphetamine treatment in rats

(2009) Keri A. Chiodo et al.   PSYCHOPHARMACOLOGY

Nicotine dependence criteria and nicotine withdrawal symptoms in relation to pain among an adult general population sample

(2008) Ulrich John et al.   EUROPEAN JOURNAL OF PAIN

A Role for Brain Stress Systems in Addiction

(2008) George F. Koob   NEURON

Chronic bupropion differentially alters the reinforcing, reward-enhancing and conditioned motivational properties of nicotine in rats

(2008) Neil Paterson et al.   NICOTINE & TOBACCO RESEARCH

MPZP: A novel small molecule corticotropin-releasing factor type 1 receptor (CRF1) antagonist

(2007) H RICHARDSON et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR