Evidence for GABA-A receptor dysregulation in gambling disorder: correlation with impulsivity

Quantification of [11C]Ro15-4513 GABAAα5 specific binding and regional selectivity in humans

(2016) Jim FM Myers et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

γ-aminobutyric acid as a metabolite: Interpreting magnetic resonance spectroscopy experiments

(2016) James FM Myers et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Using [ 11 C]Ro15 4513 PET to characterise GABA-benzodiazepine receptors in opiate addiction: Similarities and differences with alcoholism

(2016) Anne Lingford-Hughes et al.   NEUROIMAGE

The Imperial College Cambridge Manchester (ICCAM) platform study: An experimental medicine platform for evaluating new drugs for relapse prevention in addiction. Part A: Study description

(2015) Louise M Paterson et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Divergent responses of the amygdala and ventral striatum predict stress-related problem drinking in young adults: possible differential markers of affective and impulsive pathways of risk for alcohol use disorder

(2015) Y S Nikolova et al.   MOLECULAR PSYCHIATRY

From circuits to behaviour in the amygdala

(2015) Patricia H. Janak et al.   NATURE

Relationship of γ-aminobutyric acid and glutamate+glutamine concentrations in the perigenual anterior cingulate cortex with performance of Cambridge Gambling Task

(2015) Kazuyuki Fujihara et al.   NEUROIMAGE

Altered gray matter density and disrupted functional connectivity of the amygdala in adults with Internet gaming disorder

(2015) Chih-Hung Ko et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Disordered gambling: the evolving concept of behavioral addiction

(2014) Luke Clark   Annals of the New York Academy of Sciences

Striatal GABA-MRS predicts response inhibition performance and its cortical electrophysiological correlates

(2014) Clara Quetscher et al.   Brain Structure & Function

Brain γ-aminobutyric acid: a neglected role in impulsivity

(2014) Dave J. Hayes et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Acute increases in synaptic GABA detectable in the living human brain: A [11C]Ro15-4513 PET study

(2014) Paul R.A. Stokes et al.   NEUROIMAGE

Measurement of GABA using J-difference edited1H-MRS following modulation of synaptic GABA concentration with tiagabine

(2014) James F.M. Myers et al.   SYNAPSE

Frontal Lobe γ-Aminobutyric Acid Levels During Adolescence: Associations with Impulsivity and Response Inhibition

(2013) Marisa M. Silveri et al.   BIOLOGICAL PSYCHIATRY

Gamma Aminobutyric Acidergic and Neuronal Structural Markers in the Nucleus Accumbens Core Underlie Trait-like Impulsive Behavior

(2013) Daniele Caprioli et al.   BIOLOGICAL PSYCHIATRY

Connectivity-Based Functional Analysis of Dopamine Release in the Striatum Using Diffusion-Weighted MRI and Positron Emission Tomography

(2013) Andri C. Tziortzi et al.   CEREBRAL CORTEX

Disordered gambling: a behavioral addiction

(2013) Luke Clark et al.   CURRENT OPINION IN NEUROBIOLOGY

Dopaminergic and GABA-ergic markers of impulsivity in rats: evidence for anatomical localisation in ventral striatum and prefrontal cortex

(2013) Bianca Jupp et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

In vivo evidence for greater amphetamine-induced dopamine release in pathological gambling: a positron emission tomography study with [11C]-(+)-PHNO

(2013) I Boileau et al.   MOLECULAR PSYCHIATRY

GABA Levels in The Dorsal Anterior Cingulate Cortex Associated with Difficulty Ignoring Smoking-Related Cues in Tobacco-Dependent Volunteers

(2013) Amy C Janes et al.   NEUROPSYCHOPHARMACOLOGY

The D2/3dopamine receptor in pathological gambling: a positron emission tomography study with [11C]-(+)-propyl-hexahydro-naphtho-oxazin and [11C]raclopride

(2012) Isabelle Boileau et al.   ADDICTION

Distorted Expectancy Coding in Problem Gambling: Is the Addictive in the Anticipation?

(2012) Ruth J. van Holst et al.   BIOLOGICAL PSYCHIATRY

Comparison of impulsivity and working memory in cocaine addiction and pathological gambling: Implications for cocaine-induced neurotoxicity

(2012) Natalia Albein-Urios et al.   DRUG AND ALCOHOL DEPENDENCE

Characterisation of the Contribution of the GABA-Benzodiazepine α1 Receptor Subtype to [11C]Ro15-4513 PET Images

(2012) James FM Myers et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

BAP updated guidelines: evidence-based guidelines for the pharmacological management of substance abuse, harmful use, addiction and comorbidity: recommendations from BAP

(2012) AR Lingford-Hughes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Striatal dopamine D2/D3 receptor binding in pathological gambling is correlated with mood-related impulsivity

(2012) Luke Clark et al.   NEUROIMAGE

History of cigarette smoking is associated with higher limbic GABAA receptor availability

(2012) Paul R.A. Stokes et al.   NEUROIMAGE

Yohimbine-Induced Amygdala Activation in Pathological Gamblers: A Pilot Study

(2012) Igor Elman et al.   PLoS One

Dorsolateral Prefrontal γ-Aminobutyric Acid in Men Predicts Individual Differences in Rash Impulsivity

(2011) Frederic Boy et al.   BIOLOGICAL PSYCHIATRY

Schizophrenia-Like Attentional Deficits Following Blockade of Prefrontal Cortex GABAA Receptors

(2011) Tracie A Paine et al.   NEUROPSYCHOPHARMACOLOGY

Impulsive behaviour induced by both NMDA receptor antagonism and GABAA receptor activation in rat ventromedial prefrontal cortex

(2011) Emily R. Murphy et al.   PSYCHOPHARMACOLOGY

A [11C]Ro15 4513 PET study suggests that alcohol dependence in man is associated with reduced α5 benzodiazepine receptors in limbic regions

(2010) Anne Lingford-Hughes et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Brain opioid receptor binding in early abstinence from alcohol dependence and relationship to craving: An [11C]diprenorphine PET study

(2009) Tim M. Williams et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Impulsivity and response inhibition in alcohol dependence and problem gambling

(2009) Andrew J. Lawrence et al.   PSYCHOPHARMACOLOGY

GABAA-benzodiazepine receptor availability in smokers and nonsmokers: Relationship to subsyndromal anxiety and depression

(2009) Irina Esterlis et al.   SYNAPSE

Altered Cerebral γ-Aminobutyric Acid Type A–Benzodiazepine Receptor Binding in Panic Disorder Determined by [11C]Flumazenil Positron Emission Tomography

(2008) Gregor Hasler et al.   ARCHIVES OF GENERAL PSYCHIATRY

Impulsivity as a vulnerability marker for substance-use disorders: Review of findings from high-risk research, problem gamblers and genetic association studies

(2008) Antonio Verdejo-García et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS