A pH/ROS Cascade-Responsive Charge-Reversal Nanosystem with Self-Amplified Drug Release for Synergistic Oxidation-Chemotherapy

Size/Charge Changeable Acidity-Responsive Micelleplex for Photodynamic-Improved PD-L1 Immunotherapy with Enhanced Tumor Penetration

(2018) Liangliang Dai et al.   ADVANCED FUNCTIONAL MATERIALS

Thermo- and pH-dual responsive polymeric micelles with upper critical solution temperature behavior for photoacoustic imaging-guided synergistic chemo-photothermal therapy against subcutaneous and metastatic breast tumors

(2018) Zhe Yang et al.   Theranostics

Genome-Scale Modeling of NADPH-Driven β-Lapachone Sensitization in Head and Neck Squamous Cell Carcinoma

(2017) Joshua E. Lewis et al.   ANTIOXIDANTS & REDOX SIGNALING

Codelivery of a π-π Stacked Dual Anticancer Drug Combination with Nanocarriers for Overcoming Multidrug Resistance and Tumor Metastasis

(2016) Xiao Wei et al.   ADVANCED FUNCTIONAL MATERIALS

Photosensitizer enhanced disassembly of amphiphilic micelle for ROS-response targeted tumor therapy in vivo

(2016) Liangliang Dai et al.   BIOMATERIALS

Self-sufficing H2O2-responsive nanocarriers through tumor-specific H2O2 production for synergistic oxidation-chemotherapy

(2016) Junjie Li et al.   JOURNAL OF CONTROLLED RELEASE

Size Changeable Nanocarriers with Nuclear Targeting for Effectively Overcoming Multidrug Resistance in Cancer Therapy

(2015) Xing Guo et al.   ADVANCED MATERIALS

Overcoming drug-resistant lung cancer by paclitaxel loaded dual-functional liposomes with mitochondria targeting and pH-response

(2015) Lei Jiang et al.   BIOMATERIALS

Esterase-activatable β-lapachone prodrug micelles for NQO1-targeted lung cancer therapy

(2015) Xinpeng Ma et al.   JOURNAL OF CONTROLLED RELEASE

Self-delivery of a peptide-based prodrug for tumor-targeting therapy

(2015) Mengyun Peng et al.   Nano Research

Principles of nanoparticle design for overcoming biological barriers to drug delivery

(2015) Elvin Blanco et al.   NATURE BIOTECHNOLOGY

Dual-pH Sensitive Charge-Reversal Polypeptide Micelles for Tumor-Triggered Targeting Uptake and Nuclear Drug Delivery

(2015) Shi-Song Han et al.   Small

Hydrazone-Bearing PMMA-Functionalized Magnetic Nanocubes as pH-Responsive Drug Carriers for Remotely Targeted Cancer Therapy in Vitro and in Vivo

(2014) Xingwei Ding et al.   ACS Applied Materials & Interfaces

Ring-Opening Polymerization of Prodrugs: A Versatile Approach to Prepare Well-Defined Drug-Loaded Nanoparticles

(2014) Jinyao Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoencapsulation of ABT-737 and camptothecin enhances their clinical potential through synergistic antitumor effects and reduction of systemic toxicity

(2014) D Schmid et al.   Cell Death & Disease

A smart and versatile theranostic nanomedicine platform based on nanoporphyrin

(2014) Yuanpei Li et al.   Nature Communications

pH-triggered intracellular release from actively targeting polymer micelles

(2013) Xing Guo et al.   BIOMATERIALS

pH-Sensitive nano-systems for drug delivery in cancer therapy

(2013) Juan Liu et al.   BIOTECHNOLOGY ADVANCES

pH-responsive zwitterionic copolypeptides as charge conversional shielding system for gene carriers

(2013) Huayu Tian et al.   JOURNAL OF CONTROLLED RELEASE

Current Progress in Reactive Oxygen Species (ROS)-Responsive Materials for Biomedical Applications

(2013) Sue Hyun Lee et al.   Advanced Healthcare Materials

Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview

(2012) Alfred H. Schinkel et al.   ADVANCED DRUG DELIVERY REVIEWS

The Effect of Nanoparticle Size, Shape, and Surface Chemistry on Biological Systems

(2012) Alexandre Albanese et al.   Annual Review of Biomedical Engineering

Biocompatible Polymeric Nanoparticles Degrade and Release Cargo in Response to Biologically Relevant Levels of Hydrogen Peroxide

(2012) Caroline de Gracia Lux et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Biodegradable polymeric micelles for targeted and controlled anticancer drug delivery: Promises, progress and prospects

(2012) Chao Deng et al.   Nano Today

Physicochemical Characteristics of Nanoparticles Affect Circulation, Biodistribution, Cellular Internalization, and Trafficking

(2012) Xiaopin Duan et al.   Small

Sheddable Ternary Nanoparticles for Tumor Acidity-Targeted siRNA Delivery

(2011) Xian-Zhu Yang et al.   ACS Nano

The effect of surface charge on in vivo biodistribution of PEG-oligocholic acid based micellar nanoparticles

(2011) Kai Xiao et al.   BIOMATERIALS

Stability of Self-Assembled Polymeric Micelles in Serum

(2011) Jiao Lu et al.   MACROMOLECULES

Tumor delivery of macromolecular drugs based on the EPR effect

(2010) Vladimir Torchilin   ADVANCED DRUG DELIVERY REVIEWS

 -Lapachone Micellar Nanotherapeutics for Non-Small Cell Lung Cancer Therapy

(2010) E. Blanco et al.   CANCER RESEARCH

Drug Combination Studies and Their Synergy Quantification Using the Chou-Talalay Method

(2010) T.-C. Chou   CANCER RESEARCH

Actively Targeted Low-Dose Camptothecin as a Safe, Long-Acting, Disease-Modifying Nanomedicine for Rheumatoid Arthritis

(2010) Otilia May Yue Koo et al.   PHARMACEUTICAL RESEARCH

Therapeutic strategies by modulating oxygen stress in cancer and inflammation

(2009) Jun Fang et al.   ADVANCED DRUG DELIVERY REVIEWS

Super pH-sensitive multifunctional polymeric micelle for tumor pHe specific TAT exposure and multidrug resistance

(2008) Eun Seong Lee et al.   JOURNAL OF CONTROLLED RELEASE

Facile Synthesis of Well-Defined Hydrophilic Methacrylic Macromonomers Using ATRP and Click Chemistry

(2008) Paul D. Topham et al.   MACROMOLECULES

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY