Understanding the Role of the BAI Subfamily of Adhesion G Protein-Coupled Receptors (GPCRs) in Pathological and Physiological Conditions

BAI1 Suppresses Medulloblastoma Formation by Protecting p53 from Mdm2-Mediated Degradation

(2018) Dan Zhu et al.   CANCER CELL

Complement 1q like-3 protein inhibits insulin secretion from pancreatic β-cells via the cell adhesion G protein–coupled receptor BAI3

(2018) Rajesh Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Adhesion-GPCR BAI1 Promotes Excitatory Synaptogenesis by Coordinating Bidirectional Trans-synaptic Signaling

(2018) Yen-Kuei Tu et al.   JOURNAL OF NEUROSCIENCE

Spatiotemporal regulation of the GPCR activity of BAI3 by C1qL4 and Stabilin-2 controls myoblast fusion

(2018) Noumeira Hamoud et al.   Nature Communications

A disease-associated mutation in the adhesion GPCR BAI2 (ADGRB2 ) increases receptor signaling activity

(2017) Ryan H. Purcell et al.   HUMAN MUTATION

Context-dependent compensation among phosphatidylserine-recognition receptors

(2017) Kristen K. Penberthy et al.   Scientific Reports

Boosting Apoptotic Cell Clearance by Colonic Epithelial Cells Attenuates Inflammation In Vivo

(2016) Chang Sup Lee et al.   IMMUNITY

The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria

(2016) Emily A. Billings et al.   Science Signaling

The adhesion GPCR BAI1 mediates macrophage ROS production and microbicidal activity against Gram-negative bacteria

(2016) Emily A. Billings et al.   Science Signaling

Apoptotic cells trigger a membrane-initiated pathway to increase ABCA1

(2015) Aaron M. Fond et al.   JOURNAL OF CLINICAL INVESTIGATION

BAI1 regulates spatial learning and synaptic plasticity in the hippocampus

(2015) Dan Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

Dysregulation and restoration of translational homeostasis in fragile X syndrome

(2015) Joel D. Richter et al.   NATURE REVIEWS NEUROSCIENCE

Anterograde C1ql1 Signaling Is Required in Order to Determine and Maintain a Single-Winner Climbing Fiber in the Mouse Cerebellum

(2015) Wataru Kakegawa et al.   NEURON

The Secreted Protein C1QL1 and Its Receptor BAI3 Control the Synaptic Connectivity of Excitatory Inputs Converging on Cerebellar Purkinje Cells

(2015) Séverine M. Sigoillot et al.   Cell Reports

Regional distribution of synaptic markers and APP correlate with distinct clinicopathological features in sporadic and familial Alzheimer’s disease

(2014) Mitsuru Shinohara et al.   BRAIN

ATP-binding cassette transporter A1

(2014) Miranda Van Eck   CURRENT OPINION IN LIPIDOLOGY

Establishment of epithelial polarity – GEF who's minding the GAP?

(2014) Siu P. Ngok et al.   JOURNAL OF CELL SCIENCE

Changes in BAI1 and Nestin Expression Are Prognostic Indicators for Survival and Metastases in Breast Cancer and Provide Opportunities for Dual Targeted Therapies

(2014) W. H. Meisen et al.   MOLECULAR CANCER THERAPEUTICS

G-protein coupled receptor BAI3 promotes myoblast fusion in vertebrates

(2014) N. Hamoud et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The BAI subfamily of adhesion GPCRs: synaptic regulation and beyond

(2014) Jason R. Stephenson et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Distinct roles for BAI1 and TIM-4 in the engulfment of dying neurons by microglia

(2014) Fargol Mazaheri et al.   Nature Communications

Nutrition, microbiomes, and intestinal inflammation

(2013) Suzanne Devkota et al.   CURRENT OPINION IN GASTROENTEROLOGY

BAI3, CDX2 and VIL1: a panel of three antibodies to distinguish small cell from large cell neuroendocrine lung carcinomas

(2013) Muhammad F Bari et al.   HISTOPATHOLOGY

Brain-specific Angiogenesis Inhibitor-1 Signaling, Regulation, and Enrichment in the Postsynaptic Density

(2013) Jason R. Stephenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Adhesion-GPCR BAI1 Regulates Synaptogenesis by Controlling the Recruitment of the Par3/Tiam1 Polarity Complex to Synaptic Sites

(2013) J. G. Duman et al.   JOURNAL OF NEUROSCIENCE

The adhesion-GPCR BAI3, a gene linked to psychiatric disorders, regulates dendrite morphogenesis in neurons

(2013) V Lanoue et al.   MOLECULAR PSYCHIATRY

Phosphatidylserine receptor BAI1 and apoptotic cells as new promoters of myoblast fusion

(2013) Amelia E. Hochreiter-Hufford et al.   NATURE

Multiple Autism-Linked Genes Mediate Synapse Elimination via Proteasomal Degradation of a Synaptic Scaffold PSD-95

(2012) Nien-Pei Tsai et al.   CELL

Dietary and commensal derived nutrients: shaping mucosal and systemic immunity

(2012) Sean P Spencer et al.   CURRENT OPINION IN IMMUNOLOGY

Cellular Circadian Clocks in Mood Disorders

(2012) Michael J. McCarthy et al.   JOURNAL OF BIOLOGICAL RHYTHMS

Reactive Oxygen Species Produced by the NADPH Oxidase 2 Complex in Monocytes Protect Mice from Bacterial Infections

(2012) A. Pizzolla et al.   JOURNAL OF IMMUNOLOGY

LRRK2 kinase inhibition prevents pathological microglial phagocytosis in response to HIV-1 Tat protein

(2012) Daniel F Marker et al.   Journal of Neuroinflammation

A proprotein convertase/MMP-14 proteolytic cascade releases a novel 40 kDa vasculostatin from tumor suppressor BAI1

(2012) S M Cork et al.   ONCOGENE

Identification and characterization of three inherited genomic copy number variations associated with familial schizophrenia

(2012) Hsiao-Mei Liao et al.   SCHIZOPHRENIA RESEARCH

Dancing with the sterols: Critical roles for ABCG1, ABCA1, miRNAs, and nuclear and cell surface receptors in controlling cellular sterol homeostasis

(2011) Elizabeth J. Tarling et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Overexpression of MBD2 in Glioblastoma Maintains Epigenetic Silencing and Inhibits the Antiangiogenic Function of the Tumor Suppressor Gene BAI1

(2011) D. Zhu et al.   CANCER RESEARCH

Emerging roles for the BAI1 protein family in the regulation of phagocytosis, synaptogenesis, neurovasculature, and tumor development

(2011) Sarah M. Cork et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Brain angiogenesis inhibitor 1 (BAI1) is a pattern recognition receptor that mediates macrophage binding and engulfment of Gram-negative bacteria

(2011) Soumita Das et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins

(2011) M. F. Bolliger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain-specific angiogenesis inhibitor-1 expression in astrocytes and neurons: Implications for its dual function as an apoptotic engulfment receptor

(2010) Jennifer D. Sokolowski et al.   BRAIN BEHAVIOR AND IMMUNITY

Intracellular generation of superoxide by the phagocyte NADPH oxidase: How, where, and what for?

(2010) Johan Bylund et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antidepressant-like behavior in brain-specific angiogenesis inhibitor 2-deficient mice

(2010) Daisuke Okajima et al.   Journal of Physiological Sciences

Association study of six candidate genes asymmetrically expressed in the two cerebral hemispheres suggests the involvement of BAIAP2 in autism

(2010) Claudio Toma et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Brain-specific angiogenesis inhibitor 2 (BAI2) may be activated by proteolytic processing

(2010) Daisuke Okajima et al.   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Diverse somatic mutation patterns and pathway alterations in human cancers

(2010) Zhengyan Kan et al.   NATURE

Vasculostatin Inhibits Intracranial Glioma Growth and Negatively Regulates In vivo Angiogenesis through a CD36-Dependent Mechanism

(2009) B. Kaur et al.   CANCER RESEARCH

Anatomical and histological profiling of orphan G-protein-coupled receptor expression in gastrointestinal tract of C57BL/6J mice

(2009) Junko Ito et al.   CELL AND TISSUE RESEARCH

The structure and function of G-protein-coupled receptors

(2009) Daniel M. Rosenbaum et al.   NATURE

The Genetics of Symptom-Based Phenotypes: Toward a Molecular Classification of Schizophrenia

(2008) P. DeRosse et al.   SCHIZOPHRENIA BULLETIN