Preventive Leptin Administration Protects Against Sepsis Through Improving Hypotension, Tachycardia, Oxidative Stress Burst, Multiple Organ Dysfunction, and Increasing Survival

Multiple Organ Dysfunction: The Defining Syndrome of Sepsis

(2018) Markus T. Ziesmann et al.   Surgical Infections

Leptin independently predicts development of sepsis and its outcome

(2017) Sofie Jacobsson et al.   Journal of Inflammation-London

Beneficial effects of leptin treatment in a setting of cardiac dysfunction induced by transverse aortic constriction in mouse

(2017) Nieves Gómez-Hurtado et al.   JOURNAL OF PHYSIOLOGY-LONDON

Leptin Protects Against Mortality and Organ Dysfunction in A Two-Hit Trauma/Sepsis Model and is IL-6-Dependent

(2017) Lukas Leopold Negrin et al.   SHOCK

Specific Strains of Lactic Acid Bacteria Differentially Modulate the Profile of Adipokines In Vitro

(2017) Emanuel Fabersani et al.   Frontiers in Immunology

Corrigendum

(2016)   Channels

Obesity-induced Hyperleptinemia Improves Survival and Immune Response in a Murine Model of Sepsis

(2014) Daniel Siegl et al.   ANESTHESIOLOGY

Leptin Downregulates LPS-Induced Lung Injury: Role of Corticosterone and Insulin

(2014) Maristella A. Landgraf et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Sepsis-induced acute kidney injury revisited

(2014) Alexander Zarbock et al.   Current Opinion in Critical Care

20 YEARS OF LEPTIN: Connecting leptin signaling to biological function

(2014) Margaret B Allison et al.   JOURNAL OF ENDOCRINOLOGY

Diagnostic value of serum leptin and a promising novel diagnostic model for sepsis

(2014) MINGYI CHEN et al.   Experimental and Therapeutic Medicine

Leptin Attenuates Lipopolysaccharide or Oleic Acid-Induced Acute Lung Injury in Mice

(2013) Hai-Ying Dong et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock, 2012

(2013) R. P. Dellinger et al.   INTENSIVE CARE MEDICINE

Leptin Regulates KATPChannel Trafficking in Pancreatic β-Cells by a Signaling Mechanism Involving AMP-activated Protein Kinase (AMPK) and cAMP-dependent Protein Kinase (PKA)

(2013) Pei-Chun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolonged leptin treatment increases transient outward K+ current via upregulation of Kv4.2 and Kv4.3 channel subunits in adult rat ventricular myocytes

(2013) Nieves Gómez-Hurtado et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Alterations of leptin in the course of inflammation and severe sepsis

(2012) Michael Behnes et al.   BMC INFECTIOUS DISEASES

Obesity and IL-6 interact in modulating the response to endotoxemia in mice

(2012) Maria Pini et al.   CYTOKINE

The Leptin System: A Potential Target for Sepsis Induced Immune Suppression

(2012) Johannes Tschop et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Transient receptor potential melastatin 4 inhibition prevents lipopolysaccharide-induced endothelial cell death

(2011) Alvaro Becerra et al.   CARDIOVASCULAR RESEARCH

Leptin and the regulation of endothelial function in physiological and pathological conditions

(2011) Jerzy Bełtowski   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Sympathetic nervous system in obesity-related hypertension: mechanisms and clinical implications

(2011) Graziela Z Kalil et al.   HYPERTENSION RESEARCH

Hypoglycemia Revisited in the Acute Care Setting

(2011) Shih-Hung Tsai et al.   YONSEI MEDICAL JOURNAL

Long-term mortality and quality of life in sepsis: A systematic review*

(2010) Bradford D. Winters et al.   CRITICAL CARE MEDICINE

Obesity-induced Hypertension: Role of Sympathetic Nervous System, Leptin, and Melanocortins

(2010) John E. Hall et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Leptin Exacerbates Sepsis-Mediated Morbidity and Mortality

(2010) N. I. Shapiro et al.   JOURNAL OF IMMUNOLOGY

CNS Leptin Action Modulates Immune Response and Survival in Sepsis

(2010) J. Tschop et al.   JOURNAL OF NEUROSCIENCE

Relevance of Serum Leptin and Leptin-Receptor Concentrations in Critically Ill Patients

(2010) Alexander Koch et al.   MEDIATORS OF INFLAMMATION

Sepsis induced changes of adipokines and cytokines - septic patients compared to morbidly obese patients

(2010) Andreas Hillenbrand et al.   BMC Surgery

The role of the sympathetic nervous system in obesity-related hypertension

(2009) Alexandre A. da Silva et al.   CURRENT HYPERTENSION REPORTS

Early lipopolysaccharide-induced reactive oxygen species production evokes necrotic cell death in human umbilical vein endothelial cells

(2009) Felipe Simon et al.   JOURNAL OF HYPERTENSION

Antioxidant Treatment Reverses Organ Failure in Rat Model of Sepsis: Role of Antioxidant Enzymes Imbalance, Neutrophil Infiltration, and Oxidative Stress

(2009) Michael Andrades et al.   JOURNAL OF SURGICAL RESEARCH

Leptin beyond body weight regulation—Current concepts concerning its role in immune function and inflammation

(2008) Rocío Lago et al.   CELLULAR IMMUNOLOGY

Improving Outcomes for Severe Sepsis and Septic Shock: Tools for Early Identification of At-Risk Patients and Treatment Protocol Implementation

(2008) Emanuel P. Rivers et al.   CRITICAL CARE CLINICS

Crossing the Border: Developmental Regulation of Leptin Transport to the Brain

(2008) Sebastien G. Bouret   ENDOCRINOLOGY