Effect of the BH3 Mimetic Polyphenol (–)-Gossypol (AT-101) on the in vitro and in vivo Growth of Malignant Mesothelioma
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Title
Effect of the BH3 Mimetic Polyphenol (–)-Gossypol (AT-101) on the in vitro and in vivo Growth of Malignant Mesothelioma
Authors
Keywords
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Journal
Frontiers in Pharmacology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2018-11-06
DOI
10.3389/fphar.2018.01269
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Note: Only part of the references are listed.- Gossypol induces cell death by activating apoptosis and autophagy in HT-29 cells
- (2017) Ming-Dong Lu et al. Molecular Medicine Reports
- The pan-Bcl2 Inhibitor AT101 Activates the Intrinsic Apoptotic Pathway and Causes DNA Damage in Acute Myeloid Leukemia Stem-Like Cells
- (2017) Leisi Zhang et al. Targeted Oncology
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- (2017) Laura Masuelli et al. Oncotarget
- In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma
- (2017) Laura Masuelli et al. Frontiers in Pharmacology
- AT-101 acts as anti-proliferative and hormone suppressive agent in mouse pituitary corticotroph tumor cells
- (2017) B. S. Yurekli et al. JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION
- AT-101 enhances gefitinib sensitivity in non-small cell lung cancer with EGFR T790M mutations
- (2016) Ren Zhao et al. BMC CANCER
- Molecular Pharmacology of Malignant Pleural Mesothelioma: Challenges and Perspectives From Preclinical and Clinical Studies
- (2016) Stefano Thellung et al. CURRENT DRUG TARGETS
- (±)-Gossypol induces apoptosis and autophagy in head and neck carcinoma cell lines and inhibits the growth of transplanted salivary gland cancer cells in BALB/c mice
- (2016) Monica Benvenuto et al. INTERNATIONAL JOURNAL OF FOOD SCIENCES AND NUTRITION
- Mesothelioma from asbestos exposures: Epidemiologic patterns and impact in the United States
- (2016) Richard A. Lemen JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART B-CRITICAL REVIEWS
- EGFR Activation Leads to Cell Death Independent of PI3K/AKT/mTOR in an AD293 Cell Line
- (2016) Cezary Treda et al. PLoS One
- Gossypol: phytoalexin of cotton
- (2016) Xiu Tian et al. Science China-Life Sciences
- The Potential Protective Effects of Polyphenols in Asbestos-Mediated Inflammation and Carcinogenesis of Mesothelium
- (2016) Monica Benvenuto et al. Nutrients
- In vitro and in vivo inhibition of breast cancer cell growth by targeting the Hedgehog/GLI pathway with SMO (GDC-0449) or GLI (GANT-61) inhibitors
- (2016) Monica Benvenuto et al. Oncotarget
- AT101 exerts a synergetic efficacy in gastric cancer patients with 5-FU based treatment through promoting apoptosis and autophagy
- (2016) Xi Wei et al. Oncotarget
- AT-101 inhibits hedgehog pathway activity and cancer growth
- (2015) Juan Wang et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Intratumoral Pharmacokinetics: Challenges to Nanobiomaterials
- (2015) Ahmed Al-Abd et al. CURRENT PHARMACEUTICAL DESIGN
- Redox signaling: Potential arbitrator of autophagy and apoptosis in therapeutic response
- (2015) Lu Zhang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Natural humoral immune response to ribosomal P0 protein in colorectal cancer patients
- (2015) Monica Benvenuto et al. Journal of Translational Medicine
- Violacein, an indole-derived purple-colored natural pigment produced by Janthinobacterium lividum, inhibits the growth of head and neck carcinoma cell lines both in vitro and in vivo
- (2015) Laura Masuelli et al. TUMOR BIOLOGY
- P2X7 receptor-mediated PARP1 activity regulates astroglial death in the rat hippocampus following status epilepticus
- (2015) Ji Yang Kim et al. Frontiers in Cellular Neuroscience
- MicroRNAs Are Part of the Regulatory Network that Controls EGF Induced Apoptosis, Including Elements of the JAK/STAT Pathway, in A431 Cells
- (2015) Ibrahim Alanazi et al. PLoS One
- Toxicity of Gossypol from Cottonseed Cake to Sheep Ovarian Follicles
- (2015) Antônio Carlos Lopes Câmara et al. PLoS One
- Resveratrol potentiates the in vitro and in vivo anti-tumoral effects of curcumin in head and neck carcinomas
- (2015) Laura Masuelli et al. Oncotarget
- Mitogen-Activated Protein Kinase Signal Transduction in Solid Tumors
- (2014) Yuan-Yuan Lei et al. Asian Pacific Journal of Cancer Prevention
- The cytoplasmic side of p53's oncosuppressive activities
- (2014) Anna Comel et al. FEBS LETTERS
- BH3-mimetic gossypol-induced autophagic cell death in mutant BRAF melanoma cells with high expression of p21Cip1
- (2014) Gun-Hee Jang et al. LIFE SCIENCES
- Gossypol Toxicity from Cottonseed Products
- (2014) Ivana Cristina N. Gadelha et al. TheScientificWorldJOURNAL
- The Role of the Selective Adaptor p62 and Ubiquitin-Like Proteins in Autophagy
- (2014) Mónika Lippai et al. Biomed Research International
- p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents
- (2013) Xinbing Sui et al. CANCER LETTERS
- Direct Interaction of Bax and Bak Proteins with Bcl-2 Homology Domain 3 (BH3)-only Proteins in Living Cells Revealed by Fluorescence Complementation
- (2013) Laura Vela et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Induction of apoptosis and antitumor effects of a small molecule inhibitor of Bcl-2 and Bcl-xl, gossypol acetate, in multiple myeloma in vitro and in vivo
- (2013) JIE LIN et al. ONCOLOGY REPORTS
- Therapeutic potential of gossypol: An overview
- (2013) Hoda Keshmiri-Neghab et al. PHARMACEUTICAL BIOLOGY
- Combination of AT-101/cisplatin overcomes chemoresistance by inducing apoptosis and modulating epigenetics in human ovarian cancer cells
- (2012) Burcak Karaca et al. MOLECULAR BIOLOGY REPORTS
- Resveratrol and diallyl disulfide enhance curcumin-induced sarcoma cell apoptosis
- (2011) Laura Masuelli Frontiers in Bioscience-Landmark
- Endosomal Accumulation of the Activated Epidermal Growth Factor Receptor (EGFR) Induces Apoptosis
- (2011) Jamie S. Rush et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Malignant mesothelioma: Facts, Myths, and Hypotheses
- (2011) Michele Carbone et al. JOURNAL OF CELLULAR PHYSIOLOGY
- (-)-Gossypol Suppresses the Growth of Human Prostate Cancer Xenografts via Modulating VEGF Signaling-Mediated Angiogenesis
- (2011) X. Pang et al. MOLECULAR CANCER THERAPEUTICS
- Combined chemotherapy with cytotoxic and targeted compounds for the management of human malignant pleural mesothelioma
- (2011) Roberto E. Favoni et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Asbestos, Lung Cancers, and Mesotheliomas
- (2010) Nicholas H. Heintz et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Inhibition of proliferation of prostate cancer cell line, PC-3, in vitro and in vivo using (−)-gossypol
- (2010) Xian-Qing Zhang et al. ASIAN JOURNAL OF ANDROLOGY
- A natural BH3 mimetic induces autophagy in apoptosis-resistant prostate cancer via modulating Bcl-2–Beclin1 interaction at endoplasmic reticulum
- (2010) J Lian et al. CELL DEATH AND DIFFERENTIATION
- The Bcl-2 Homology Domain 3 Mimetic Gossypol Induces Both Beclin 1-dependent and Beclin 1-independent Cytoprotective Autophagy in Cancer Cells
- (2010) Ping Gao et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Autophagy: assays and artifacts
- (2010) Sandra Barth et al. JOURNAL OF PATHOLOGY
- The Pan-Bcl-2 Inhibitor (-)-Gossypol Triggers Autophagic Cell Death in Malignant Glioma
- (2010) V. Voss et al. MOLECULAR CANCER RESEARCH
- Gossypol Induces Apoptosis by Activating p53 in Prostate Cancer Cells and Prostate Tumor-Initiating Cells
- (2010) S. R. Volate et al. MOLECULAR CANCER THERAPEUTICS
- Cullin3-Based Polyubiquitination and p62-Dependent Aggregation of Caspase-8 Mediate Extrinsic Apoptosis Signaling
- (2009) Zhaoyu Jin et al. CELL
- Bcl-2 Inhibitors: Targeting Mitochondrial Apoptotic Pathways in Cancer Therapy
- (2009) M. H. Kang et al. CLINICAL CANCER RESEARCH
- ERK and cell death: Mechanisms of ERK-induced cell death - apoptosis, autophagy and senescence
- (2009) Sebastien Cagnol et al. FEBS Journal
- The autophagy effector Beclin 1: a novel BH3-only protein
- (2009) S Sinha et al. ONCOGENE
- AT-101, a small molecule inhibitor of anti-apoptotic Bcl-2 family members, activates the SAPK/JNK pathway and enhances radiation-induced apoptosis
- (2009) Shuraila F Zerp et al. Radiation Oncology
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