Suramin, screened from an approved drug library, inhibits HuR functions and attenuates malignant phenotype of oral cancer cells

Low-dose suramin in autism spectrum disorder: a small, phase I/II, randomized clinical trial

(2017) Robert K. Naviaux et al.   Annals of Clinical and Translational Neurology

Uncovering the molecular and physiological processes of anticancer leads binding human serum albumin: A physical insight into drug efficacy

(2017) Chuanbo Liu et al.   PLoS One

The fungal natural product azaphilone-9 binds to HuR and inhibits HuR-RNA interaction in vitro

(2017) Kawaljit Kaur et al.   PLoS One

The RNA binding protein HuR determines the differential translation of autism-associated FoxP subfamily members in the developing neocortex

(2016) T. Popovitchenko et al.   Scientific Reports

Posttranslational control of HuR function

(2016) Ioannis Grammatikakis et al.   Wiley Interdisciplinary Reviews-RNA

Identification and Validation of Novel Small Molecule Disruptors of HuR-mRNA Interaction

(2015) Xiaoqing Wu et al.   ACS Chemical Biology

Pharmacodynamics of Telomerase Inhibition and Telomere Shortening by Noncytotoxic Suramin

(2014) Yuebo Gan et al.   AAPS Journal

Surface plasmon resonance spectroscopy for characterisation of membrane protein–ligand interactions and its potential for drug discovery

(2013) Simon G. Patching   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Suramin inhibits PDGF-stimulated receptor phosphorylation, proteoglycan synthesis and glycosaminoglycan hyperelongation in human vascular smooth muscle cells

(2013) Peter J. Little et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Biologic Mechanisms of Oral Cancer Pain and Implications for Clinical Therapy

(2011) C.T. Viet et al.   JOURNAL OF DENTAL RESEARCH

The RNA-Binding Protein HuR Promotes Glioma Growth and Treatment Resistance

(2011) N. Filippova et al.   MOLECULAR CANCER RESEARCH

The X-ray Crystal Structure of the First RNA Recognition Motif and Site-Directed Mutagenesis Suggest a Possible HuR Redox Sensing Mechanism

(2010) Roger Marc Benoit et al.   JOURNAL OF MOLECULAR BIOLOGY

Tandem Phosphorylation of Serines 221 and 318 by Protein Kinase C  Coordinates mRNA Binding and Nucleocytoplasmic Shuttling of HuR

(2010) A. Doller et al.   MOLECULAR AND CELLULAR BIOLOGY

HuR Knockdown Changes the Oncogenic Potential of Oral Cancer Cells

(2010) W. Kakuguchi et al.   MOLECULAR CANCER RESEARCH

HuR expression in the nucleus correlates with high histological grade and poor disease-free survival in ovarian cancer

(2009) Xiaofang YI et al.   AUSTRALIAN & NEW ZEALAND JOURNAL OF OBSTETRICS & GYNAECOLOGY

HuR is exported to the cytoplasm in oral cancer cells in a different manner from that of normal cells

(2009) H Hasegawa et al.   BRITISH JOURNAL OF CANCER

The Role of HuR in Gemcitabine Efficacy in Pancreatic Cancer: HuR Up-regulates the Expression of the Gemcitabine Metabolizing Enzyme Deoxycytidine Kinase

(2009) C. L. Costantino et al.   CANCER RESEARCH

Chemical inhibitors destabilize HuR binding to the AU-rich element of TNF-α mRNA

(2009) Min-Ju Chae et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Regulation of non-AU-rich element containing c-fms proto-oncogene expression by HuR in breast cancer

(2009) H-H Woo et al.   ONCOGENE

Diverse molecular functions of Hu proteins

(2008) M. N. Hinman et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Terminal Adenosyl Transferase Activity of Posttranscriptional Regulator HuR Revealed by Confocal On-Bead Screening

(2008) Nicole-Claudia Meisner et al.   JOURNAL OF MOLECULAR BIOLOGY