Is plasminogen activator inhibitor-1 a physiological bottleneck bridging major depressive disorder and cardiovascular disease?

Inflammation and Immune Regulation as Potential Drug Targets in Antidepressant Treatment

(2016) Frank M. Schmidt et al.   Current Neuropharmacology

A meta-analysis of blood cytokine network alterations in psychiatric patients: comparisons between schizophrenia, bipolar disorder and depression

(2016) D R Goldsmith et al.   MOLECULAR PSYCHIATRY

Preexisting mild sleep disturbance as a vulnerability factor for inflammation-induced depressed mood: a human experimental study

(2016) H J Cho et al.   Translational Psychiatry

Epidemiology of venous thromboembolism (VTE) associated with pregnancy

(2015) Leonid A. Parunov et al.   BIRTH DEFECTS RESEARCH PART C-EMBRYO TODAY-REVIEWS

Relationship between Circulating Tumor Cells, Blood Coagulation, and Urokinase-Plasminogen-Activator System in Early Breast Cancer Patients

(2015) Michal Mego et al.   Breast Journal

The Effect of PAI-1 4G/5G Polymorphism and Clinical Factors on Coronary Artery Occlusion in Myocardial Infarction

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Antidepressant-like effect of n-3 PUFAs in CUMS rats: role of tPA/PAI-1 system

(2015) Mimi Tang et al.   PHYSIOLOGY & BEHAVIOR

High Incidence of ACE/PAI-1 in Association to a Spectrum of Other Polymorphic Cardiovascular Genes Involving PBMCs Proinflammatory Cytokines in Hypertensive Hypercholesterolemic Patients: Reversibility with a Combination of ACE Inhibitor and Statin

(2015) Jeanne d’Arc AlBacha et al.   PLoS One

The 4G/4G Genotype of PAI-1 Polymorphism Is Associated with Higher Plasma PAI-1 Concentrations and Mortality in Patients with Severe Sepsis

(2015) Leonardo Lorente et al.   PLoS One

Tissue plasminogen activator inhibits NMDA-receptor-mediated increases in calcium levels in cultured hippocampal neurons

(2015) Samuel D. Robinson et al.   Frontiers in Cellular Neuroscience

Impacts of tissue-type plasminogen activator (tPA) on neuronal survival

(2015) Arnaud Chevilley et al.   Frontiers in Cellular Neuroscience

Predictive value of ankle-brachial index and PAI-1 in symptomatic intracranial atherosclerotic disease recurrence

(2014) A. Massot et al.   ATHEROSCLEROSIS

Ideal Cardiovascular Health

(2014) Vanessa Xanthakis et al.   CIRCULATION

A review of the relationship between proinflammatory cytokines and major depressive disorder

(2014) Juan Joseph Young et al.   JOURNAL OF AFFECTIVE DISORDERS

Blood coagulation and fibrinolysis in patients with Cushing’s syndrome: Increased plasminogen activator inhibitor-1, decreased tissue factor pathway inhibitor, and unchanged thrombin-activatable fibrinolysis inhibitor levels

(2014) C. Erem et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

17β-Estradiol Differentially Regulates Stress Circuitry Activity in Healthy and Depressed Women

(2014) Emily G Jacobs et al.   NEUROPSYCHOPHARMACOLOGY

Roux-en-Y Gastric Bypass Decreases Pro-inflammatory and Thrombotic Biomarkers in Individuals with Extreme Obesity

(2014) Bárbara Dal Molin Netto et al.   OBESITY SURGERY

Exogenous t-PA Administration Increases Hippocampal Mature BDNF Levels. Plasmin- or NMDA-Dependent Mechanism?

(2014) Marion Rodier et al.   PLoS One

The association between sleep characteristics and prothrombotic markers in a population-based sample: Chicago Area Sleep Study

(2014) Zehra Tosur et al.   SLEEP MEDICINE

Functional Stability of Plasminogen Activator Inhibitor-1

(2014) Songul Yasar Yildiz et al.   TheScientificWorldJOURNAL

Residual vein thrombosis and onset of post-thrombotic syndrome: Influence of the 4G/5G polymorphism of plasminogen activator inhibitor-1 gene

(2014) Egle Incalcaterra et al.   THROMBOSIS RESEARCH

The role of coagulation/fibrinolysis during Streptococcus pyogenes infection

(2014) Torsten G. Loof et al.   Frontiers in Cellular and Infection Microbiology

Depression With Atypical Features and Increase in Obesity, Body Mass Index, Waist Circumference, and Fat Mass

(2014) Aurélie M. Lasserre et al.   JAMA Psychiatry

Prognostic Value of Depression, Anxiety, and Anger in Hospitalized Cardiovascular Disease Patients for Predicting Adverse Cardiac Outcomes

(2013) Shunichi Nakamura et al.   AMERICAN JOURNAL OF CARDIOLOGY

The Epidemiology of Depression Across Cultures

(2013) Ronald C. Kessler et al.   Annual Review of Public Health

Depression and cardiovascular disease: a clinical review

(2013) D. L. Hare et al.   EUROPEAN HEART JOURNAL

Association of a prothrombotic state with left-ventricular diastolic dysfunction in hypertension

(2013) Cristiana Catena et al.   JOURNAL OF HYPERTENSION

BDNF: an indicator of insomnia?

(2013) M Giese et al.   MOLECULAR PSYCHIATRY

Serum BDNF concentrations as peripheral manifestations of depression: evidence from a systematic review and meta-analyses on 179 associations (N=9484)

(2013) M L Molendijk et al.   MOLECULAR PSYCHIATRY

Association of Plasminogen Activator Inhibitor-Type 1 (-675 4G/5G) Polymorphism with Pre-Eclampsia: Systematic Review

(2013) Jessie A. Morgan et al.   PLoS One

Depression and Cardiovascular Disease

(2013) Larkin Elderon et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Self-reported sleep disturbance is associated with elevated levels of PAI-1 in individuals with a recorded history of depressive symptoms

(2013) Antti-Pekka Elomaa et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England

(2013) A. Abdul Sultan et al.   BMJ-British Medical Journal

Burden of Depressive Disorders by Country, Sex, Age, and Year: Findings from the Global Burden of Disease Study 2010

(2013) Alize J. Ferrari et al.   PLOS MEDICINE

Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study

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Do negative emotional factors have independent associations with excess adiposity?

(2012) Misty A.W. Hawkins et al.   JOURNAL OF PSYCHOSOMATIC RESEARCH

Heartache and heartbreak—the link between depression and cardiovascular disease

(2012) Charles B. Nemeroff et al.   Nature Reviews Cardiology

BDNF Val66Met Impairs Fluoxetine-Induced Enhancement of Adult Hippocampus Plasticity

(2012) Kevin G Bath et al.   NEUROPSYCHOPHARMACOLOGY

Sigma-1 receptor chaperone and brain-derived neurotrophic factor: Emerging links between cardiovascular disease and depression

(2012) Kenji Hashimoto   PROGRESS IN NEUROBIOLOGY

Inflammatory biomarkers predict depressive, but not anxiety symptoms during aging: The prospective Sydney Memory and Aging Study

(2012) B.T. Baune et al.   PSYCHONEUROENDOCRINOLOGY

Synaptic Dysfunction in Depression: Potential Therapeutic Targets

(2012) R. S. Duman et al.   SCIENCE

Targeting sigma-1 receptor signaling by endogenous ligands for cardioprotection

(2011) Md. Shenuarin Bhuiyan et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Coagulation and prothrombotic state parameters: a clinical analysis during early pregnancy

(2011) H. Chen et al.   IRISH JOURNAL OF MEDICAL SCIENCE

Insomnia as a predictor of depression: A meta-analytic evaluation of longitudinal epidemiological studies

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PAI-1 in tissue fibrosis

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Intravenous Thrombolytic Therapy for Acute Ischemic Stroke

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The Roles of BDNF in the Pathophysiology of Major Depression and in Antidepressant Treatment

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Forty Years Later and the Role of Plasminogen Activator Inhibitor Type 2/SERPINB2 Is Still an Enigma

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Pre-eclampsia

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The role of plasminogen activator inhibitor 1 in renal and cardiovascular diseases

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Approaches to transport therapeutic drugs across the blood–brain barrier to treat brain diseases

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Neurocircuitry of Mood Disorders

(2009) Joseph L Price et al.   NEUROPSYCHOPHARMACOLOGY

A Reproductive Subtype of Depression

(2009) Jennifer L. Payne et al.   HARVARD REVIEW OF PSYCHIATRY

General Cardiovascular Risk Profile for Use in Primary Care

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A systematic review and meta-analysis of clinical studies on major depression and BDNF levels: implications for the role of neuroplasticity in depression

(2008) André Russowsky Brunoni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Major Depressive Disorder

(2008) R.H. Belmaker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Plasminogen activator inhibitor-1 gene is associated with major depression and antidepressant treatment response

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Cardiovascular, Inflammatory, and Metabolic Consequences of Sleep Deprivation

(2008) Janet M. Mullington et al.   PROGRESS IN CARDIOVASCULAR DISEASES

Association between Anxiety and Factors of Coagulation and Fibrinolysis

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The HPA axis in major depression: classical theories and new developments

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