Cryo-EM structure of Hepatitis C virus IRES bound to the human ribosome at 3.9-Å resolution

The Scanning Mechanism of Eukaryotic Translation Initiation

(2014) Alan G. Hinnebusch   Annual Review of Biochemistry

Initiation of Translation by Cricket Paralysis Virus IRES Requires Its Translocation in the Ribosome

(2014) Israel S. Fernández et al.   CELL

Structure of the Mammalian Ribosome-Sec61 Complex to 3.4 Å Resolution

(2014) Rebecca M. Voorhees et al.   CELL

Structural Changes Enable Start Codon Recognition by the Eukaryotic Translation Initiation Complex

(2014) Tanweer Hussain et al.   CELL

Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA

(2014) Yury S. Polikanov et al.   MOLECULAR CELL

Structure of the mammalian 80S initiation complex with initiation factor 5B on HCV-IRES RNA

(2014) Hiroshi Yamamoto et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Purification, characterization and crystallization of the human 80S ribosome

(2014) Heena Khatter et al.   NUCLEIC ACIDS RESEARCH

Kinetic pathway of 40S ribosomal subunit recruitment to hepatitis C virus internal ribosome entry site

(2014) Gabriele Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Base pairing between hepatitis C virus RNA and 18S rRNA is required for IRES-dependent translation initiation in vivo

(2014) D. Matsuda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure of the Mammalian Ribosomal 43S Preinitiation Complex Bound to the Scanning Factor DHX29

(2013) Yaser Hashem et al.   CELL

Hepatitis-C-virus-like internal ribosome entry sites displace eIF3 to gain access to the 40S subunit

(2013) Yaser Hashem et al.   NATURE

Quantifying the local resolution of cryo-EM density maps

(2013) Alp Kucukelbir et al.   NATURE METHODS

Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

(2013) Xueming Li et al.   NATURE METHODS

The crystal structure of the eukaryotic 40S ribosomal subunit in complex with eIF1 and eIF1A

(2013) Melanie Weisser et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Prevention of overfitting in cryo-EM structure determination

(2012) Sjors H W Scheres et al.   NATURE METHODS

HCV IRES manipulates the ribosome to promote the switch from translation initiation to elongation

(2012) Megan E Filbin et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Structure of a hepatitis C virus RNA domain in complex with a translation inhibitor reveals a binding mode reminiscent of riboswitches

(2012) S. M. Dibrov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting Ribosome assembly on the HCV RNA using a small RNA molecule

(2012) Prasanna Bhat et al.   RNA Biology

Introduction: A smouldering public-health crisis

(2011) Lauren Gravitz   NATURE

HCV IRES domain IIb affects the configuration of coding RNA in the 40S subunit's decoding groove

(2011) M. E. Filbin et al.   RNA

The Structure of the Eukaryotic Ribosome at 3.0 A Resolution

(2011) A. Ben-Shem et al.   SCIENCE

Crystal Structure of the HCV IRES Central Domain Reveals Strategy for Start-Codon Positioning

(2011) Katherine E. Berry et al.   STRUCTURE

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The HCV IRES pseudoknot positions the initiation codon on the 40S ribosomal subunit

(2010) K. E. Berry et al.   RNA

The importance of inter- and intramolecular base pairing for translation reinitiation on a eukaryotic bicistronic mRNA

(2009) C. Luttermann et al.   GENES & DEVELOPMENT

RPS25 is essential for translation initiation by the Dicistroviridae and hepatitis C viral IRESs

(2009) D. M. Landry et al.   GENES & DEVELOPMENT

Conserved functional domains and a novel tertiary interaction near the pseudoknot drive translational activity of hepatitis C virus and hepatitis C virus-like internal ribosome entry sites

(2009) Laura E. Easton et al.   NUCLEIC ACIDS RESEARCH

An Improved Cryogen for Plunge Freezing

(2008) William F. Tivol et al.   MICROSCOPY AND MICROANALYSIS