The past, present and future of light-gated ion channels and optogenetics

Dopamine neurons create Pavlovian conditioned stimuli with circuit-defined motivational properties

(2018) Benjamin T. Saunders et al.   NATURE NEUROSCIENCE

Structural mechanisms of selectivity and gating in anion channelrhodopsins

(2018) Hideaki E. Kato et al.   NATURE

Crystal structure of the natural anion-conducting channelrhodopsin GtACR1

(2018) Yoon Seok Kim et al.   NATURE

Temporally precise single-cell-resolution optogenetics

(2017) Or A. Shemesh et al.   NATURE NEUROSCIENCE

Optogenetic Tools for Subcellular Applications in Neuroscience

(2017) Benjamin R. Rost et al.   NEURON

The form and function of channelrhodopsin

(2017) Karl Deisseroth et al.   SCIENCE

Competition between engrams influences fear memory formation and recall

(2016) A. J. Rashid et al.   SCIENCE

Optogenetics: 10 years of microbial opsins in neuroscience

(2015) Karl Deisseroth   NATURE NEUROSCIENCE

Structure-Guided Transformation of Channelrhodopsin into a Light-Activated Chloride Channel

(2014) A. Berndt et al.   SCIENCE

Conversion of Channelrhodopsin into a Light-Gated Chloride Channel

(2014) J. Wietek et al.   SCIENCE

Enhancement of encoding and retrieval functions through theta phase-specific manipulation of hippocampus

(2014) Joshua H Siegle et al.   eLife

Diverging neural pathways assemble a behavioural state from separable features in anxiety

(2013) Sung-Yon Kim et al.   NATURE

Crystal structure of the channelrhodopsin light-gated cation channel

(2012) Hideaki E. Kato et al.   NATURE

Optogenetic stimulation of a hippocampal engram activates fear memory recall

(2012) Xu Liu et al.   NATURE

Functional identification of an aggression locus in the mouse hypothalamus

(2011) Dayu Lin et al.   NATURE

Neocortical excitation/inhibition balance in information processing and social dysfunction

(2011) Ofer Yizhar et al.   NATURE

Molecular and Cellular Approaches for Diversifying and Extending Optogenetics

(2010) Viviana Gradinaru et al.   CELL

High-performance genetically targetable optical neural silencing by light-driven proton pumps

(2010) Brian Y. Chow et al.   NATURE

Regulation of parkinsonian motor behaviours by optogenetic control of basal ganglia circuitry

(2010) Alexxai V. Kravitz et al.   NATURE

Ultrafast optogenetic control

(2010) Lisa A Gunaydin et al.   NATURE NEUROSCIENCE

Temporally precise in vivo control of intracellular signalling

(2009) Raag D. Airan et al.   NATURE

Bi-stable neural state switches

(2009) André Berndt et al.   NATURE NEUROSCIENCE

Phasic Firing in Dopaminergic Neurons Is Sufficient for Behavioral Conditioning

(2009) H.-C. Tsai et al.   SCIENCE

Red-shifted optogenetic excitation: a tool for fast neural control derived from Volvox carteri

(2008) Feng Zhang et al.   NATURE NEUROSCIENCE