Multiple components of the nuclear pore complex interact with the amino-terminus of MX2 to facilitate HIV-1 restriction

Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2

(2018) Melissa Kane et al.   eLife

Capsid-Dependent Host Factors in HIV-1 Infection

(2017) Masahiro Yamashita et al.   TRENDS IN MICROBIOLOGY

CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction

(2017) Frances J. D. Alvarez et al.   Science Advances

Accumulation of MxB/Mx2-resistant HIV-1 Capsid Variants During Expansion of the HIV-1 Epidemic in Human Populations

(2016) Wei Wei et al.   EBioMedicine

A Triple-Arginine Motif in the Amino-Terminal Domain and Oligomerization Are Required for HIV-1 Inhibition by Human MX2

(2015) Caroline Goujon et al.   JOURNAL OF VIROLOGY

Oligomerization Requirements for MX2-Mediated Suppression of HIV-1 Infection

(2015) Matthew D. J. Dicks et al.   JOURNAL OF VIROLOGY

Contribution of MxB Oligomerization to HIV-1 Capsid Binding and Restriction

(2015) Cindy Buffone et al.   JOURNAL OF VIROLOGY

The highly polymorphic cyclophilin A-binding loop in HIV-1 capsid modulates viral resistance to MxB

(2015) Zhenlong Liu et al.   Retrovirology

Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export

(2015) Sarah A. Port et al.   Cell Reports

Structural Insight into HIV-1 Restriction by MxB

(2014) Jennifer L. Fribourgh et al.   Cell Host & Microbe

Transportin-1 and Transportin-2: Protein nuclear import and beyond

(2014) Laure Twyffels et al.   FEBS LETTERS

Host and Viral Determinants of Mx2 Antiretroviral Activity

(2014) Idoia Busnadiego et al.   JOURNAL OF VIROLOGY

Transfer of the Amino-Terminal Nuclear Envelope Targeting Domain of Human MX2 Converts MX1 into an HIV-1 Resistance Factor

(2014) C. Goujon et al.   JOURNAL OF VIROLOGY

Transportin acts to regulate mitotic assembly events by target binding rather than Ran sequestration

(2014) Cyril Bernis et al.   MOLECULAR BIOLOGY OF THE CELL

Antibody-Free Magnetic Cell Sorting of Genetically Modified Primary Human CD4+ T Cells by One-Step Streptavidin Affinity Purification

(2014) Nicholas J. Matheson et al.   PLoS One

MxB binds to the HIV-1 core and prevents the uncoating process of HIV-1

(2014) Thomas Fricke et al.   Retrovirology

The Interferon-Inducible MxB Protein Inhibits HIV-1 Infection

(2013) Zhenlong Liu et al.   Cell Host & Microbe

Human MX2 is an interferon-induced post-entry inhibitor of HIV-1 infection

(2013) Caroline Goujon et al.   NATURE

MX2 is an interferon-induced inhibitor of HIV-1 infection

(2013) Melissa Kane et al.   NATURE

Nucleoporin NUP153 Phenylalanine-Glycine Motifs Engage a Common Binding Pocket within the HIV-1 Capsid Protein to Mediate Lentiviral Infectivity

(2013) Kenneth A. Matreyek et al.   PLoS Pathogens

Human Nucleoporins Promote HIV-1 Docking at the Nuclear Pore, Nuclear Import and Integration

(2012) Francesca Di Nunzio et al.   PLoS One

The Structure of the Nuclear Pore Complex

(2011) André Hoelz et al.   Annual Review of Biochemistry

HIV-1 remodels the nuclear pore complex

(2011) Anne Monette et al.   JOURNAL OF CELL BIOLOGY

The Requirement for Nucleoporin NUP153 during Human Immunodeficiency Virus Type 1 Infection Is Determined by the Viral Capsid

(2011) K. A. Matreyek et al.   JOURNAL OF VIROLOGY

HIV-1 Capsid-Cyclophilin Interactions Determine Nuclear Import Pathway, Integration Targeting and Replication Efficiency

(2011) Torsten Schaller et al.   PLoS Pathogens

HIV Integration Targeting: A Pathway Involving Transportin-3 and the Nuclear Pore Protein RanBP2

(2011) Karen E. Ocwieja et al.   PLoS Pathogens

Flexible Use of Nuclear Import Pathways by HIV-1

(2010) KyeongEun Lee et al.   Cell Host & Microbe

Human MxA Protein: An Interferon-Induced Dynamin-Like GTPase with Broad Antiviral Activity

(2010) Otto Haller et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Structural basis of oligomerization in the stalk region of dynamin-like MxA

(2010) Song Gao et al.   NATURE

Flexible Gates: Dynamic Topologies and Functions for FG Nucleoporins in Nucleocytoplasmic Transport

(2009) Laura J. Terry et al.   EUKARYOTIC CELL

Human Immunodeficiency Virus Type 1 (HIV-1) Induces the Cytoplasmic Retention of Heterogeneous Nuclear Ribonucleoprotein A1 by Disrupting Nuclear Import

(2009) Anne Monette et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Requirement for Cellular Transportin 3 (TNPO3 or TRN-SR2) during Infection Maps to Human Immunodeficiency Virus Type 1 Capsid and Not Integrase

(2009) L. Krishnan et al.   JOURNAL OF VIROLOGY

Global Analysis of Host-Pathogen Interactions that Regulate Early-Stage HIV-1 Replication

(2008) Renate König et al.   CELL

Transportin-SR2 Imports HIV into the Nucleus

(2008) Frauke Christ et al.   CURRENT BIOLOGY

Chemokine receptor CCR2 undergoes transportin1-dependent nuclear translocation

(2008) Nicolas Favre et al.   PROTEOMICS