Genetically modified pigs are protected from classical swine fever virus

Multi-resistance strategy for viral diseases and in vitro short hairpin RNA verification method in pigs

(2018) Jong-nam Oh et al.   ASIAN-AUSTRALASIAN JOURNAL OF ANIMAL SCIENCES

Antiviral RNA interference in mammals

(2018) Shou-Wei Ding et al.   CURRENT OPINION IN IMMUNOLOGY

Efficient targeted integration into the bovine Rosa26 locus using TALENs

(2018) Ming Wang et al.   Scientific Reports

CRISPR/Cas9-mediated targeting of the Rosa26 locus produces Cre reporter rat strains for monitoring Cre-loxP -mediated lineage tracing

(2017) Yuanwu Ma et al.   FEBS Journal

Human Virus-Derived Small RNAs Can Confer Antiviral Immunity in Mammals

(2017) Yang Qiu et al.   IMMUNITY

Classical Swine Fever—An Updated Review

(2017) Sandra Blome et al.   Viruses-Basel

Optimization of a CRISPR/Cas9-mediated Knock-in Strategy at the Porcine Rosa26 Locus in Porcine Foetal Fibroblasts

(2017) Zicong Xie et al.   Scientific Reports

Precision engineering for PRRSV resistance in pigs: Macrophages from genome edited pigs lacking CD163 SRCR5 domain are fully resistant to both PRRSV genotypes while maintaining biological function

(2017) Christine Burkard et al.   PLoS Pathogens

Increased Neutralizing Antibody Production and Interferon-γ Secretion in Response to Porcine Reproductive and Respiratory Syndrome Virus Immunization in Genetically Modified Pigs

(2017) Guangping Huang et al.   Frontiers in Immunology

RNA interference screening of interferon-stimulated genes with antiviral activities against classical swine fever virus using a reporter virus

(2016) Xiao Wang et al.   ANTIVIRAL RESEARCH

Guanylate-Binding Protein 1, an Interferon-Induced GTPase, Exerts an Antiviral Activity against Classical Swine Fever Virus Depending on Its GTPase Activity

(2016) Lian-Feng Li et al.   JOURNAL OF VIROLOGY

Alteration of a Second Putative Fusion Peptide of Structural Glycoprotein E2 of Classical Swine Fever Virus Alters Virus Replication and Virulence in Swine

(2016) L. G. Holinka et al.   JOURNAL OF VIROLOGY

Entry of Classical Swine Fever Virus into PK-15 Cells via a pH-, Dynamin-, and Cholesterol-Dependent, Clathrin-Mediated Endocytic Pathway That Requires Rab5 and Rab7

(2016) Bao-Jun Shi et al.   JOURNAL OF VIROLOGY

Replacement of Porcine CD163 Scavenger Receptor Cysteine-Rich Domain 5 with a CD163-Like Homolog Confers Resistance of Pigs to Genotype 1 but Not Genotype 2 Porcine Reproductive and Respiratory Syndrome Virus

(2016) Kevin D. Wells et al.   JOURNAL OF VIROLOGY

Induction and suppression of antiviral RNA interference by influenza A virus in mammalian cells

(2016) Yang Li et al.   Nature Microbiology

Identification and characterization of rabbit ROSA26 for gene knock-in and stable reporter gene expression

(2016) Dongshan Yang et al.   Scientific Reports

Rosa26-targeted sheep gene knock-in via CRISPR-Cas9 system

(2016) Mingming Wu et al.   Scientific Reports

Thioredoxin 2 Is a Novel E2-Interacting Protein That Inhibits the Replication of Classical Swine Fever Virus

(2015) Su Li et al.   JOURNAL OF VIROLOGY

The Laminin Receptor Is a Cellular Attachment Receptor for Classical Swine Fever Virus

(2015) Jianing Chen et al.   JOURNAL OF VIROLOGY

Gene-edited pigs are protected from porcine reproductive and respiratory syndrome virus

(2015) Kristin M Whitworth et al.   NATURE BIOTECHNOLOGY

Genome-wide inactivation of porcine endogenous retroviruses (PERVs)

(2015) L. Yang et al.   SCIENCE

Heat shock protein 70 is associated with CSFV NS5A protein and enhances viral RNA replication

(2015) Chengcheng Zhang et al.   VIROLOGY

Studying classical swine fever virus: Making the best of a bad virus

(2015) Wei Ji et al.   VIRUS RESEARCH

Transgenic shRNA pigs reduce susceptibility to foot and mouth disease virus infection

(2015) Shengwei Hu et al.   eLife

The control of classical swine fever in wild boar

(2015) Volker Moennig   Frontiers in Microbiology

Genetic variability and distribution of Classical swine fever virus

(2015) Martin Beer et al.   ANIMAL HEALTH RESEARCH REVIEWS

Inhibition of Dengue Virus 2 Replication by Artificial MicroRNAs Targeting the Conserved Regions

(2015) Pei-wen Xie et al.   Nucleic Acid Therapeutics

Generation of Gene-Modified Cynomolgus Monkey via Cas9/RNA-Mediated Gene Targeting in One-Cell Embryos

(2014) Yuyu Niu et al.   CELL

Rosa26-targeted swine models for stable gene over-expression and Cre-mediated lineage tracing

(2014) Xiaoping Li et al.   CELL RESEARCH

Dimeric CRISPR RNA-guided FokI nucleases for highly specific genome editing

(2014) Shengdar Q Tsai et al.   NATURE BIOTECHNOLOGY

Fusion of catalytically inactive Cas9 to FokI nuclease improves the specificity of genome modification

(2014) John P Guilinger et al.   NATURE BIOTECHNOLOGY

Molecular beacon–enabled purification of living cells by targeting cell type–specific mRNAs

(2014) Brian M Wile et al.   Nature Protocols

Rosa26 Locus Supports Tissue-Specific Promoter Driving Transgene Expression Specifically in Pig

(2014) Qingran Kong et al.   PLoS One

Classical swine fever in China: A minireview

(2014) Yuzi Luo et al.   VETERINARY MICROBIOLOGY

Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression

(2013) Lei S. Qi et al.   CELL

One-Step Generation of Mice Carrying Reporter and Conditional Alleles by CRISPR/Cas-Mediated Genome Engineering

(2013) Hui Yang et al.   CELL

Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity

(2013) F. Ann Ran et al.   CELL

Correction of a Genetic Disease in Mouse via Use of CRISPR-Cas9

(2013) Yuxuan Wu et al.   Cell Stem Cell

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

The Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction

(2013) Keerthi Gottipati et al.   PLoS Pathogens

A pipeline for the generation of shRNA transgenic mice

(2012) Lukas E Dow et al.   Nature Protocols

RNAimmuno: A database of the nonspecific immunological effects of RNA interference and microRNA reagents

(2012) M. Olejniczak et al.   RNA

In vitro inhibition of CSFV replication by multiple siRNA expression

(2011) Jiangnan Li et al.   ANTIVIRAL RESEARCH

Functional Identification of Optimized RNAi Triggers Using a Massively Parallel Sensor Assay

(2011) Christof Fellmann et al.   MOLECULAR CELL

Suppression of Avian Influenza Transmission in Genetically Modified Chickens

(2011) J. Lyall et al.   SCIENCE

In vitro inhibition of CSFV replication by retroviral vector-mediated RNA interference

(2010) Jiangnan Li et al.   JOURNAL OF VIROLOGICAL METHODS

A three-dimensional view of the molecular machinery of RNA interference

(2009) Martin Jinek et al.   NATURE

Transgene Expression Is Associated with Copy Number and Cytomegalovirus Promoter Methylation in Transgenic Pigs

(2009) Qingran Kong et al.   PLoS One

In vitro inhibition of classical swine fever virus replication by siRNAs targeting Npro and NS5B genes

(2008) Xingran Xu et al.   ANTIVIRAL RESEARCH

Recent advances in the development of recombinant vaccines against classical swine fever virus: Cellular responses also play a role in protection

(2007) Llilianne Ganges et al.   VETERINARY JOURNAL