Computational translation of genomic responses from experimental model systems to humans

Of Mice and Men: Comparative Analysis of Neuro-Inflammatory Mechanisms in Human and Mouse Using Cause-and-Effect Models

(2017) Alpha Tom Kodamullil et al.   JOURNAL OF ALZHEIMERS DISEASE

Comprehensive comparison of molecular portraits between cell lines and tumors in breast cancer

(2016) Guanglong Jiang et al.   BMC GENOMICS

Mouse Genome Database (MGD)-2017: community knowledge resource for the laboratory mouse

(2016) Judith A. Blake et al.   NUCLEIC ACIDS RESEARCH

Molecular analysis of urothelial cancer cell lines for modeling tumor biology and drug response

(2016) M L Nickerson et al.   ONCOGENE

Mouse Genome Informatics (MGI): reflecting on 25 years

(2015) Janan T. Eppig et al.   MAMMALIAN GENOME

Tumor-Derived Cell Lines as Molecular Models of Cancer Pharmacogenomics

(2015) A. Goodspeed et al.   MOLECULAR CANCER RESEARCH

Evidence-Based Translation for the Genomic Responses of Murine Models for the Study of Human Immunity

(2015) Junhee Seok   PLoS One

Transforming Growth Factor β–induced Protein Promotes Severe Vascular Inflammatory Responses

(2014) Jong-Sup Bae et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge

(2014) Kahn Rhrissorrakrai et al.   BIOINFORMATICS

CD28 Homodimer Interface Mimetic Peptide Acts as a Preventive and Therapeutic Agent in Models of Severe Bacterial Sepsis and Gram-Negative Bacterial Peritonitis

(2014) Girish Ramachandran et al.   JOURNAL OF INFECTIOUS DISEASES

Gene Ontology Consortium: going forward

(2014)   NUCLEIC ACIDS RESEARCH

Genomic responses in mouse models greatly mimic human inflammatory diseases

(2014) Keizo Takao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Treatment of heterotopic ossification through remote ATP hydrolysis

(2014) J. R. Peterson et al.   Science Translational Medicine

The species translation challenge—A systems biology perspective on human and rat bronchial epithelial cells

(2014) Carine Poussin et al.   Scientific Data

The Reactome pathway knowledgebase

(2013) David Croft et al.   NUCLEIC ACIDS RESEARCH

Genomic responses in mouse models poorly mimic human inflammatory diseases

(2013) Junhee Seok et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Evaluating cell lines as tumour models by comparison of genomic profiles

(2013) Silvia Domcke et al.   Nature Communications

From Mouse to Human: Evolutionary Genomics Analysis of Human Orthologs of Essential Genes

(2013) Benjamin Georgi et al.   PLoS Genetics

Hepatic induction of cholesterol biosynthesis reflects a remote adaptive response to pneumococcal pneumonia

(2012) Martina Weber et al.   FASEB JOURNAL

A genomic storm in critically injured humans

(2011) Wenzhong Xiao et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Thrombin generation in severe sepsis

(2011) S. Petros et al.   THROMBOSIS RESEARCH

Interspecies Translation of Disease Networks Increases Robustness and Predictive Accuracy

(2011) Seyed Yahya Anvar et al.   PLoS Computational Biology

Multiscale model for the assessment of autonomic dysfunction in human endotoxemia

(2010) Panagiota T. Foteinou et al.   PHYSIOLOGICAL GENOMICS

Systematic discovery of nonobvious human disease models through orthologous phenotypes

(2010) K. L. McGary et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reconstituting Organ-Level Lung Functions on a Chip

(2010) D. Huh et al.   SCIENCE

Two Genes on A/J Chromosome 18 Are Associated with Susceptibility to Staphylococcus aureus Infection by Combined Microarray and QTL Analyses

(2010) Sun-Hee Ahn et al.   PLoS Pathogens

Gene-expression profiling of peripheral blood mononuclear cells in sepsis

(2009) Didier Payen et al.   CRITICAL CARE MEDICINE

Genomic expression profiling across the pediatric systemic inflammatory response syndrome, sepsis, and septic shock spectrum*

(2009) Hector R. Wong et al.   CRITICAL CARE MEDICINE

Gene-expression profiling of peripheral blood mononuclear cells in sepsis*

(2009) Benjamin M. P. Tang et al.   CRITICAL CARE MEDICINE

Perfused multiwell plate for 3D liver tissue engineering

(2009) Karel Domansky et al.   LAB ON A CHIP

Genomic transcriptional profiling identifies a candidate blood biomarker signature for the diagnosis of septicemic melioidosis

(2009) Rungnapa Pankla et al.   GENOME BIOLOGY

Comparison of longitudinal leukocyte gene expression after burn injury or trauma-hemorrhage in mice

(2007) James A. Lederer et al.   PHYSIOLOGICAL GENOMICS