Precision in a rush: Trade-offs between reproducibility and steepness of the hunchback expression pattern

LlamaTags: A Versatile Tool to Image Transcription Factor Dynamics in Live Embryos

(2018) Jacques P. Bothma et al.   CELL

Dense Bicoid hubs accentuate binding along the morphogen gradient

(2017) Mustafa Mir et al.   GENES & DEVELOPMENT

Decoding of position in the developing neural tube from antiparallel morphogen gradients

(2017) Marcin Zagorski et al.   SCIENCE

Decoding temporal interpretation of the morphogen Bicoid in the early Drosophila embryo

(2017) Anqi Huang et al.   eLife

Concentration dependent chromatin states induced by the bicoid morphogen gradient

(2017) Colleen E Hannon et al.   eLife

Information Integration and Energy Expenditure in Gene Regulation

(2016) Javier Estrada et al.   CELL

Fundamental Limits to Cellular Sensing

(2016) Pieter Rein ten Wolde et al.   JOURNAL OF STATISTICAL PHYSICS

Precision of Readout at the hunchback Gene: Analyzing Short Transcription Time Traces in Living Fly Embryos

(2016) Jonathan Desponds et al.   PLoS Computational Biology

Trade-Offs in Delayed Information Transmission in Biochemical Networks

(2015) F. Mancini et al.   JOURNAL OF STATISTICAL PHYSICS

Combining protein and mRNA quantification to decipher transcriptional regulation

(2015) Heng Xu et al.   NATURE METHODS

Properties of cooperatively induced phases in sensing models

(2015) Stuart A. Sevier et al.   PHYSICAL REVIEW E

The Berg-Purcell Limit Revisited

(2014) Kazunari Kaizu et al.   BIOPHYSICAL JOURNAL

Positional Information, Positional Error, and Readout Precision in Morphogenesis: A Mathematical Framework

(2014) G. Tka ik et al.   GENETICS

How input noise limits biochemical sensing in ultrasensitive systems

(2014) Bo Hu et al.   PHYSICAL REVIEW E

Promoter architecture dictates cell-to-cell variability in gene expression

(2014) Daniel L. Jones et al.   SCIENCE

Kinetic competition during the transcription cycle results in stochastic RNA processing

(2014) Antoine Coulon et al.   eLife

Live Imaging of Bicoid-Dependent Transcription in Drosophila Embryos

(2013) Tanguy Lucas et al.   CURRENT BIOLOGY

Quantitative Imaging of Transcription in Living Drosophila Embryos Links Polymerase Activity to Patterning

(2013) Hernan G. Garcia et al.   CURRENT BIOLOGY

Effect of ligand diffusion on occupancy fluctuations of cell-surface receptors

(2013) Alexander M. Berezhkovskii et al.   JOURNAL OF CHEMICAL PHYSICS

Positional information, in bits

(2013) J. O. Dubuis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SGNS2: a compartmentalized stochastic chemical kinetics simulator for dynamic cell populations

(2012) Jason Lloyd-Price et al.   BIOINFORMATICS

Precision of Hunchback Expression in the Drosophila Embryo

(2012) Michael W. Perry et al.   CURRENT BIOLOGY

A Linear Framework for Time-Scale Separation in Nonlinear Biochemical Systems

(2012) Jeremy Gunawardena   PLoS One

Operator Sequence Alters Gene Expression Independently of Transcription Factor Occupancy in Bacteria

(2012) Hernan G. Garcia et al.   Cell Reports

Mutual Repression Enhances the Steepness and Precision of Gene Expression Boundaries

(2012) Thomas R. Sokolowski et al.   PLoS Computational Biology

Dynamics of Cooperativity in Chemical Sensing among Cell-Surface Receptors

(2011) Monica Skoge et al.   PHYSICAL REVIEW LETTERS

Multiple enhancers ensure precision of gap gene-expression patterns in the Drosophila embryo

(2011) M. W. Perry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High Mobility of Bicoid Captured by Fluorescence Correlation Spectroscopy: Implication for the Rapid Establishment of Its Gradient

(2010) Asmahan Abu-Arish et al.   BIOPHYSICAL JOURNAL

The gap gene network

(2010) Johannes Jaeger   CELLULAR AND MOLECULAR LIFE SCIENCES

The Bicoid Morphogen System

(2010) Aude Porcher et al.   CURRENT BIOLOGY

The time to measure positional information: maternal Hunchback is required for the synchrony of the Bicoid transcriptional response at the onset of zygotic transcription

(2010) A. Porcher et al.   DEVELOPMENT

Bicoid - morphogen function revisited

(2010) Ulrike Löhr et al.   FLY

Role of Spatial Averaging in the Precision of Gene Expression Patterns

(2009) Thorsten Erdmann et al.   PHYSICAL REVIEW LETTERS

Antagonistic action of Bicoid and the repressor Capicua determines the spatial limits of Drosophila head gene expression domains

(2009) U. Lohr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulatory activity revealed by dynamic correlations in gene expression noise

(2008) Mary J Dunlop et al.   NATURE GENETICS

Cooperativity, Sensitivity, and Noise in Biochemical Signaling

(2008) William Bialek et al.   PHYSICAL REVIEW LETTERS