A Linear Framework for Time-Scale Separation in Nonlinear Biochemical Systems

Some lessons about models from Michaelis and Menten

(2012) Jeremy Gunawardena   MOLECULAR BIOLOGY OF THE CELL

An Algebraic Approach to Signaling Cascades with n Layers

(2011) Elisenda Feliu et al.   BULLETIN OF MATHEMATICAL BIOLOGY

Identification of the Catalytic Mechanism and Estimation of Kinetic Parameters for Fumarase

(2011) Muriel Mescam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Comparative analysis of Erk phosphorylation suggests a mixed strategy for measuring phospho-form distributions

(2011) S. Prabakaran et al.   Molecular Systems Biology

The cis-Regulatory Logic of Hedgehog Gradient Responses: Key Roles for Gli Binding Affinity, Competition, and Cooperativity

(2011) D. S. Parker et al.   Science Signaling

Phosphorylation Barcoding as a Mechanism of Directing GPCR Signaling

(2011) S. B. Liggett   Science Signaling

Dynamics within the CD95 death-inducing signaling complex decide life and death of cells

(2010) Leo Neumann et al.   Molecular Systems Biology

Tubulin post-translational modifications: encoding functions on the neuronal microtubule cytoskeleton

(2010) Carsten Janke et al.   TRENDS IN NEUROSCIENCES

Thermodynamics-Based Models of Transcriptional Regulation by Enhancers: The Roles of Synergistic Activation, Cooperative Binding and Short-Range Repression

(2010) Xin He et al.   PLoS Computational Biology

A multi-time-scale analysis of chemical reaction networks: I. Deterministic systems

(2009) Chang Hyeong Lee et al.   JOURNAL OF MATHEMATICAL BIOLOGY

Toric dynamical systems

(2009) Gheorghe Craciun et al.   JOURNAL OF SYMBOLIC COMPUTATION

The rational parameterisation theorem for multisite post-translational modification systems

(2009) Matthew Thomson et al.   JOURNAL OF THEORETICAL BIOLOGY

Evidence that Fold-Change, and Not Absolute Level, of β-Catenin Dictates Wnt Signaling

(2009) Lea Goentoro et al.   MOLECULAR CELL

Unlimited multistability in multisite phosphorylation systems

(2009) Matthew Thomson et al.   NATURE

G-Protein-Coupled Receptors: From Classical Modes of Modulation to Allosteric Mechanisms

(2008) Thomas M. Bridges et al.   ACS Chemical Biology

Predicting expression patterns from regulatory sequence in Drosophila segmentation

(2008) Eran Segal et al.   NATURE

Analysis of combinatorial cis-regulation in synthetic and genomic promoters

(2008) Jason Gertz et al.   NATURE

A quantitative model of transcription factor–activated gene expression

(2008) Harold D Kim et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

G-protein-coupled receptors: past, present and future

(2006) Stephen J Hill   BRITISH JOURNAL OF PHARMACOLOGY

Agonist-activated ion channels

(2006) David Colquhoun   BRITISH JOURNAL OF PHARMACOLOGY