SIRT1 plays a neuroprotective role in traumatic brain injury in rats via inhibiting the p38 MAPK pathway

Traumatic Brain Injury and Mitochondrial Dysfunction

(2015) John B. Hiebert et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury

(2015) Wang-Xia Wang et al.   EXPERIMENTAL NEUROLOGY

The role of p38MAPK signal pathway in the neuroprotective mechanism of limb postconditioning against rat cerebral ischemia/reperfusion injury

(2015) Hao Li et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Biochanin A protects against focal cerebral ischemia/reperfusion in rats via inhibition of p38-mediated inflammatory responses

(2015) Wenbo Wang et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Suppression of mitochondrial fission in experimental cerebral ischemia: The potential neuroprotective target of p38 MAPK inhibition

(2015) Xue-mei Zhang et al.   NEUROCHEMISTRY INTERNATIONAL

SIRT1 protects rat lung tissue against severe burn-induced remote ALI by attenuating the apoptosis of PMVECs via p38 MAPK signaling

(2015) Xiaozhi Bai et al.   Scientific Reports

Taurine attenuates amyloid β 1–42-induced mitochondrial dysfunction by activating of SIRT1 in SK-N-SH cells

(2014) Qinru Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Evidence to support mitochondrial neuroprotection, in severe traumatic brain injury

(2014) Shyam Gajavelli et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

SIRT1 inhibition by sirtinol aggravates brain edema after experimental subarachnoid hemorrhage

(2014) Xiao-Ming Zhou et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Melatonin prevents cell death and mitochondrial dysfunction via a SIRT1-dependent mechanism during ischemic-stroke in mice

(2014) Yang Yang et al.   JOURNAL OF PINEAL RESEARCH

Alpha-lipoic acid upregulates SIRT1-dependent PGC-1α expression and protects mouse brain against focal ischemia

(2014) B. Fu et al.   NEUROSCIENCE

SIRT1 Activating compounds reduce oxidative stress mediated neuronal loss in viral induced CNS demyelinating disease

(2014) Reas S Khan et al.   Acta Neuropathologica Communications

The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease

(2013) T. Jayasena et al.   AGEING RESEARCH REVIEWS

p38 and JNK MAPK pathways control the balance of apoptosis and autophagy in response to chemotherapeutic agents

(2013) Xinbing Sui et al.   CANCER LETTERS

Citicoline (CDP-choline) increases Sirtuin1 expression concomitant to neuroprotection in experimental stroke

(2013) Olivia Hurtado et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial respiratory chain and creatine kinase activities following trauma brain injury in brain of mice preconditioned with N-methyl-d-aspartate

(2013) Carina R. Boeck et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Silent Information Regulator 1 Protects the Brain Against Cerebral Ischemic Damage

(2013) M. Hernandez-Jimenez et al.   STROKE

Superimposed traumatic brain injury modulates vasomotor responses in third-order vessels after hemorrhagic shock

(2013) Bo Chen et al.   Scandinavian Journal of Trauma Resuscitation & Emergency Medicine

The role of sirtuins in Alzheimer's disease

(2013) Rakhee Lalla et al.   Frontiers in Aging Neuroscience

Polydatin, a natural polyphenol, protects arterial smooth muscle cells against mitochondrial dysfunction and lysosomal destabilization following hemorrhagic shock

(2012) Xingmin Wang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

SIRT1 modulates MAPK pathways in ischemic–reperfused cardiomyocytes

(2012) Matteo Becatti et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Interactions between SIRT1 and MAPK/ERK regulate neuronal apoptosis induced by traumatic brain injury in vitro and in vivo

(2012) Yongbo Zhao et al.   EXPERIMENTAL NEUROLOGY

Polydatin – a new mitochondria protector for acute severe hemorrhagic shock treatment

(2012) Xingmin Wang et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Effects of sirtuin 1 activation on nicotine and lipopolysaccharide-induced cytotoxicity and inflammatory cytokine production in human gingival fibroblasts

(2012) G-J. Park et al.   JOURNAL OF PERIODONTAL RESEARCH

Are sirtuins viable targets for improving healthspan and lifespan?

(2012) Joseph A. Baur et al.   NATURE REVIEWS DRUG DISCOVERY

SIRT1 activating compounds reduce oxidative stress and prevent cell death in neuronal cells

(2012) Reas S. Khan et al.   Frontiers in Cellular Neuroscience

Role of SIRT1 in Heat Stress- and Lipopolysaccharide-induced Immune and Defense Gene Expression in Human Dental Pulp Cells

(2011) Sang-Im Lee et al.   JOURNAL OF ENDODONTICS

Axonal Degeneration Is Mediated by the Mitochondrial Permeability Transition Pore

(2011) S. A. Barrientos et al.   JOURNAL OF NEUROSCIENCE

Regulation of Autophagy by Kinases

(2011) Savitha Sridharan et al.   Cancers

Mammalian Sirtuins: Biological Insights and Disease Relevance

(2010) Marcia C. Haigis et al.   Annual Review of Pathology-Mechanisms of Disease

Involvement of pro- and anti-inflammatory cytokines and chemokines in the pathophysiology of traumatic brain injury

(2010) Jenna M. Ziebell et al.   Neurotherapeutics

Sirtuin 1 regulation of developmental genes during differentiation of stem cells

(2010) V. Calvanese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Repeated preconditioning with hyperbaric oxygen induces neuroprotection against forebrain ischemia via suppression of p38 mitogen activated protein kinase

(2009) Satoshi Yamashita et al.   BRAIN RESEARCH

Icariin enhances neuronal survival after oxygen and glucose deprivation by increasing SIRT1

(2009) Lin Wang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Molecular and immunocytochemical characterization of primary neuronal cultures from adult rat brain: Differential expression of neuronal and glial protein markers

(2009) Balmiki Ray et al.   JOURNAL OF NEUROSCIENCE METHODS

Anti-inflammatory treatment with the p38 mitogen-activated protein kinase inhibitor SB239063 is neuroprotective, decreases the number of activated microglia and facilitates neurogenesis in oxygen–glucose-deprived hippocampal slice cultures

(2008) Maria Strassburger et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Brain SIRT1: Anatomical Distribution and Regulation by Energy Availability

(2008) G. Ramadori et al.   JOURNAL OF NEUROSCIENCE

Sirtuins — novel therapeutic targets to treat age-associated diseases

(2008) Siva Lavu et al.   NATURE REVIEWS DRUG DISCOVERY